SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pe5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3004_1
(SERUM ALBUMIN)		 3pe5 UNCHARACTERIZED
PROTEIN
([Clostridium]
leptum) 		4 / 6 PHE A 199
PHE A 267
LEU A 206
VAL A 275
 None
 1.05A 1hk1A-3pe5A:
undetectable		 1hk1A-3pe5A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3pe5 UNCHARACTERIZED
PROTEIN
([Clostridium]
leptum) 		4 / 7 ILE A 136
ILE A 177
LEU A 143
LEU A 354
 None
 0.81A 3adxA-3pe5A:
undetectable		 3adxA-3pe5A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOB_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3pe5 UNCHARACTERIZED
PROTEIN
([Clostridium]
leptum) 		5 / 12 GLN A 264
THR A 261
PHE A 267
GLY A 115
LEU A 272
 None
 1.50A 3aobC-3pe5A:
undetectable		 3aobC-3pe5A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_1
(UNCHARACTERIZED
PROTEIN)		 3pe5 UNCHARACTERIZED
PROTEIN
([Clostridium]
leptum) 		3 / 3 THR A 373
LYS A 276
GLU A 360
 None
 0.94A 3ijdB-3pe5A:
undetectable		 3ijdB-3pe5A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 3pe5 UNCHARACTERIZED
PROTEIN
([Clostridium]
leptum) 		3 / 3 GLY A 171
TRP A 159
VAL A 156
 None
 0.72A 3n62B-3pe5A:
undetectable		 3n62B-3pe5A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 3pe5 UNCHARACTERIZED
PROTEIN
([Clostridium]
leptum) 		3 / 3 GLY A 171
TRP A 159
VAL A 156
 None
 0.69A 3n65B-3pe5A:
undetectable		 3n65B-3pe5A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 3pe5 UNCHARACTERIZED
PROTEIN
([Clostridium]
leptum) 		3 / 3 GLY A 171
TRP A 159
VAL A 156
 None
 0.73A 3n66B-3pe5A:
undetectable		 3n66B-3pe5A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_1
(REGULATORY PROTEIN
TETR)		 3pe5 UNCHARACTERIZED
PROTEIN
([Clostridium]
leptum) 		4 / 8 GLY A 339
ARG A 150
VAL A 341
ASP A 151
 None
 0.97A 5vlmA-3pe5A:
undetectable		 5vlmA-3pe5A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3pe5 UNCHARACTERIZED
PROTEIN
([Clostridium]
leptum) 		5 / 12 GLU A 303
GLY A 306
VAL A 295
LEU A 292
ILE A 299
 None
 1.18A 5vopB-3pe5A:
undetectable		 5vopB-3pe5A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_ACTB804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3pe5 UNCHARACTERIZED
PROTEIN
([Clostridium]
leptum) 		3 / 3 GLY A 171
TRP A 159
VAL A 156
 None
 0.70A 5vuoB-3pe5A:
undetectable		 5vuoB-3pe5A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 3pe5 UNCHARACTERIZED
PROTEIN
([Clostridium]
leptum) 		3 / 3 ASP A 266
PHE A 258
ARG A 324
 None
 1.05A 5yw0A-3pe5A:
undetectable		 5yw0A-3pe5A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CJK_C_ACTC301_0
(IMMUNOGLOBULIN FAB
LIGHT CHAIN)		 3pe5 UNCHARACTERIZED
PROTEIN
([Clostridium]
leptum) 		4 / 4 VAL A 341
GLY A 339
ASP A 335
ASP A 337
 None
 1.45A 6cjkC-3pe5A:
undetectable		 6cjkC-3pe5A:
19.90