SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3peh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3peh ENDOPLASMIN HOMOLOG
(Plasmodium
falciparum) 		5 / 11 ARG A 134
THR A 147
GLY A 150
GLU A 132
ILE A 114
 SO4  A   1 (-3.8A)
SO4  A   1 (-3.2A)
None
None
None
 1.30A 1odiA-3pehA:
undetectable		 1odiA-3pehA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_B_ADNB1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3peh ENDOPLASMIN HOMOLOG
(Plasmodium
falciparum) 		5 / 11 ARG A 134
THR A 147
GLY A 150
GLU A 132
ILE A 114
 SO4  A   1 (-3.8A)
SO4  A   1 (-3.2A)
None
None
None
 1.27A 1odiB-3pehA:
undetectable		 1odiB-3pehA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3peh ENDOPLASMIN HOMOLOG
(Plasmodium
falciparum) 		5 / 11 ARG A 134
THR A 147
GLY A 150
GLU A 132
ILE A 114
 SO4  A   1 (-3.8A)
SO4  A   1 (-3.2A)
None
None
None
 1.26A 1odiC-3pehA:
undetectable		 1odiC-3pehA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3peh ENDOPLASMIN HOMOLOG
(Plasmodium
falciparum) 		5 / 11 ARG A 134
THR A 147
GLY A 150
GLU A 132
ILE A 114
 SO4  A   1 (-3.8A)
SO4  A   1 (-3.2A)
None
None
None
 1.28A 1odiD-3pehA:
undetectable		 1odiD-3pehA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3peh ENDOPLASMIN HOMOLOG
(Plasmodium
falciparum) 		5 / 11 ARG A 134
THR A 147
GLY A 150
GLU A 132
ILE A 114
 SO4  A   1 (-3.8A)
SO4  A   1 (-3.2A)
None
None
None
 1.29A 1odiE-3pehA:
undetectable		 1odiE-3pehA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3peh ENDOPLASMIN HOMOLOG
(Plasmodium
falciparum) 		5 / 11 ARG A 134
THR A 147
GLY A 150
GLU A 132
ILE A 114
 SO4  A   1 (-3.8A)
SO4  A   1 (-3.2A)
None
None
None
 1.29A 1odiF-3pehA:
undetectable		 1odiF-3pehA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S14_A_NOVA1300_1
(TOPOISOMERASE IV
SUBUNIT B)		 3peh ENDOPLASMIN HOMOLOG
(Plasmodium
falciparum) 		5 / 12 ASP A 109
ASP A 148
MET A 153
ASP A 212
THR A 241
 None
IBD  A1001 (-3.4A)
IBD  A1001 (-3.8A)
None
IBD  A1001 (-3.6A)
 1.35A 1s14A-3pehA:
10.5		 1s14A-3pehA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3peh ENDOPLASMIN HOMOLOG
(Plasmodium
falciparum) 		3 / 3 ASP A 302
ASP A 298
ASN A 281
 None
 0.83A 2bm9D-3pehA:
undetectable		 2bm9D-3pehA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1001_0
(ALDEHYDE
DEHYDROGENASE A)		 3peh ENDOPLASMIN HOMOLOG
(Plasmodium
falciparum) 		4 / 7 LEU A 245
ILE A 243
ASN A 106
PHE A 194
 None
None
IBD  A1001 ( 4.0A)
IBD  A1001 ( 4.3A)
 0.94A 2opxA-3pehA:
undetectable		 2opxA-3pehA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1500_1
(CYTOCHROME P450 3A4)		 3peh ENDOPLASMIN HOMOLOG
(Plasmodium
falciparum) 		5 / 11 LEU A 100
ILE A 243
PHE A  99
ALA A 197
LEU A 247
 None
 1.39A 2v0mA-3pehA:
undetectable		 2v0mA-3pehA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S45_B_478B201_1
(PROTEASE)		 3peh ENDOPLASMIN HOMOLOG
(Plasmodium
falciparum) 		5 / 9 ASP A  86
ILE A  87
ILE A 165
ILE A 187
ILE A  88
 None
None
IBD  A1001 (-4.6A)
None
None
 0.87A 3s45A-3pehA:
undetectable		 3s45A-3pehA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3peh ENDOPLASMIN HOMOLOG
(Plasmodium
falciparum) 		5 / 10 ARG A 134
THR A 147
GLY A 150
GLU A 132
ILE A 114
 SO4  A   1 (-3.8A)
SO4  A   1 (-3.2A)
None
None
None
 1.34A 3uayA-3pehA:
undetectable		 3uayA-3pehA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9L_A_CAMA1419_0
(CYTOCHROME P450)		 3peh ENDOPLASMIN HOMOLOG
(Plasmodium
falciparum) 		5 / 12 ILE A 228
GLY A 152
THR A 241
VAL A 206
ILE A 217
 None
IBD  A1001 (-3.9A)
IBD  A1001 (-3.6A)
None
None
 1.01A 4c9lA-3pehA:
undetectable		 4c9lA-3pehA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9L_B_CAMB1419_0
(CYTOCHROME P450)		 3peh ENDOPLASMIN HOMOLOG
(Plasmodium
falciparum) 		5 / 12 ILE A 228
GLY A 152
THR A 241
VAL A 206
ILE A 217
 None
IBD  A1001 (-3.9A)
IBD  A1001 (-3.6A)
None
None
 1.02A 4c9lB-3pehA:
undetectable		 4c9lB-3pehA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_A_CAMA423_0
(CYTOCHROME P450)		 3peh ENDOPLASMIN HOMOLOG
(Plasmodium
falciparum) 		5 / 12 ILE A 228
GLY A 152
THR A 241
VAL A 206
ILE A 217
 None
IBD  A1001 (-3.9A)
IBD  A1001 (-3.6A)
None
None
 1.03A 4c9oA-3pehA:
undetectable		 4c9oA-3pehA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_B_CAMB423_0
(CYTOCHROME P450)		 3peh ENDOPLASMIN HOMOLOG
(Plasmodium
falciparum) 		5 / 12 ILE A 228
GLY A 152
THR A 241
VAL A 206
ILE A 217
 None
IBD  A1001 (-3.9A)
IBD  A1001 (-3.6A)
None
None
 1.03A 4c9oB-3pehA:
undetectable		 4c9oB-3pehA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_2
(PROTEASE)		 3peh ENDOPLASMIN HOMOLOG
(Plasmodium
falciparum) 		3 / 3 LEU A 255
ASP A 262
ILE A 264
 None
 0.53A 6dh0B-3pehA:
undetectable		 6dh0B-3pehA:
16.87