SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pf2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
4 / 7 ILE A 236
LEU A 240
THR A 270
LEU A 271
None
0.73A 1v54N-3pf2A:
undetectable
1v54W-3pf2A:
undetectable
1v54N-3pf2A:
18.65
1v54W-3pf2A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
4 / 7 ILE A 236
LEU A 240
THR A 270
LEU A 271
None
0.74A 1v55A-3pf2A:
undetectable
1v55J-3pf2A:
undetectable
1v55A-3pf2A:
18.65
1v55J-3pf2A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
4 / 7 ILE A 236
LEU A 240
THR A 270
LEU A 271
None
0.73A 2dyrN-3pf2A:
undetectable
2dyrW-3pf2A:
undetectable
2dyrN-3pf2A:
18.65
2dyrW-3pf2A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
4 / 8 ILE A 236
LEU A 240
THR A 270
LEU A 271
None
0.69A 2eijN-3pf2A:
undetectable
2eijW-3pf2A:
undetectable
2eijN-3pf2A:
18.65
2eijW-3pf2A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
4 / 8 ILE A 236
LEU A 240
THR A 270
LEU A 271
None
0.70A 2eikN-3pf2A:
undetectable
2eikW-3pf2A:
undetectable
2eikN-3pf2A:
18.65
2eikW-3pf2A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
4 / 8 ILE A 236
LEU A 240
THR A 270
LEU A 271
None
0.72A 2eilN-3pf2A:
undetectable
2eilW-3pf2A:
undetectable
2eilN-3pf2A:
18.65
2eilW-3pf2A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3A_A_TOPA1190_1
(DIHYDROFOLATE
REDUCTASE)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
5 / 11 ILE A 292
PHE A 294
ILE A 236
PRO A 237
THR A 249
None
1.26A 2w3aA-3pf2A:
undetectable
2w3aA-3pf2A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
5 / 12 ILE A 437
SER A 493
ALA A 508
LEU A 345
ILE A 449
None
1.10A 2xkwB-3pf2A:
undetectable
2xkwB-3pf2A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y4N_B_PACB503_0
(PHENYLACETATE-COENZY
ME A LIGASE)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
4 / 4 SER A 505
GLY A 346
GLY A 382
LYS A 450
None
1.38A 2y4nB-3pf2A:
undetectable
2y4nB-3pf2A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
4 / 7 ILE A 236
LEU A 240
THR A 270
LEU A 271
None
0.81A 3ablA-3pf2A:
undetectable
3ablJ-3pf2A:
undetectable
3ablA-3pf2A:
18.65
3ablJ-3pf2A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
4 / 8 ILE A 236
LEU A 240
THR A 270
LEU A 271
None
0.68A 3ablN-3pf2A:
undetectable
3ablW-3pf2A:
undetectable
3ablN-3pf2A:
18.65
3ablW-3pf2A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
4 / 7 ILE A 236
LEU A 240
THR A 270
LEU A 271
None
0.78A 3ag3A-3pf2A:
undetectable
3ag3J-3pf2A:
undetectable
3ag3A-3pf2A:
18.65
3ag3J-3pf2A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
4 / 8 ILE A 236
LEU A 240
THR A 270
LEU A 271
None
0.75A 3ag3N-3pf2A:
undetectable
3ag3W-3pf2A:
undetectable
3ag3N-3pf2A:
18.65
3ag3W-3pf2A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
4 / 8 ILE A 236
LEU A 240
THR A 270
LEU A 271
None
0.76A 3asnN-3pf2A:
undetectable
3asnW-3pf2A:
undetectable
3asnN-3pf2A:
18.65
3asnW-3pf2A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_B_URFB400_1
(URIDINE
PHOSPHORYLASE 1)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
4 / 8 THR A 223
GLY A 381
LEU A 452
ILE A 449
None
0.92A 3nbqB-3pf2A:
undetectable
3nbqB-3pf2A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_C_URFC400_1
(URIDINE
PHOSPHORYLASE 1)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
4 / 8 THR A 223
GLY A 381
LEU A 452
ILE A 449
None
0.85A 3nbqC-3pf2A:
undetectable
3nbqC-3pf2A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_1
(16S RRNA METHYLASE)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
3 / 3 ASP A 511
GLU A 392
SER A 490
None
0.82A 3p2kA-3pf2A:
undetectable
3p2kA-3pf2A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUN_A_CCSA165_0
(LYSOZYME)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
3 / 3 ASN A 421
ALA A 420
LYS A 450
None
0.95A 3runA-3pf2A:
undetectable
3runA-3pf2A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_1
(PROTEASE)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
5 / 12 LEU A 331
ASP A 204
GLY A 241
ILE A 266
ILE A 236
None
0.84A 3s54A-3pf2A:
undetectable
3s54A-3pf2A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_B_0LIB1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
5 / 9 ILE A 302
LEU A 271
ILE A 264
MET A 309
ILE A 333
None
1.27A 3zosB-3pf2A:
undetectable
3zosB-3pf2A:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM7_A_29JA603_1
(TRANSPORTER)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
5 / 10 TYR A 454
SER A 490
GLY A 381
ASP A 500
THR A 499
None
1.36A 4mm7A-3pf2A:
undetectable
4mm7A-3pf2A:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA302_1
(CHITOSANASE)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
4 / 5 THR A 391
THR A 393
ASP A 389
TYR A 478
None
1.24A 4oltA-3pf2A:
undetectable
4oltA-3pf2A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB302_1
(CHITOSANASE)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
4 / 5 THR A 391
THR A 393
ASP A 389
TYR A 478
None
1.26A 4oltB-3pf2A:
undetectable
4oltB-3pf2A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
4 / 7 THR A 380
LEU A 417
ASN A 421
SER A 493
None
1.11A 4pfjA-3pf2A:
undetectable
4pfjA-3pf2A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_A_HQEA503_1
(CATALASE)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
5 / 9 PRO A 206
PHE A 246
LEU A 331
LEU A 355
PHE A 353
None
1.32A 4qopA-3pf2A:
undetectable
4qopA-3pf2A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_B_HQEB503_1
(CATALASE)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
5 / 9 PRO A 206
PHE A 246
LEU A 331
LEU A 355
PHE A 353
None
1.32A 4qopB-3pf2A:
undetectable
4qopB-3pf2A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA302_1
(CHITOSANASE)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
4 / 5 THR A 391
THR A 393
ASP A 389
TYR A 478
None
1.26A 4qwpA-3pf2A:
undetectable
4qwpA-3pf2A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB306_1
(CHITOSANASE)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
4 / 5 THR A 391
THR A 393
ASP A 389
TYR A 478
None
1.25A 4qwpB-3pf2A:
undetectable
4qwpB-3pf2A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
4 / 7 ILE A 236
LEU A 240
THR A 270
LEU A 271
None
0.77A 5b1aA-3pf2A:
undetectable
5b1aJ-3pf2A:
undetectable
5b1aA-3pf2A:
18.65
5b1aJ-3pf2A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
4 / 7 ILE A 236
LEU A 240
THR A 270
LEU A 271
None
0.77A 5b1bA-3pf2A:
undetectable
5b1bJ-3pf2A:
undetectable
5b1bA-3pf2A:
18.65
5b1bJ-3pf2A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
4 / 7 ILE A 236
LEU A 240
THR A 270
LEU A 271
None
0.78A 5b3sA-3pf2A:
undetectable
5b3sJ-3pf2A:
undetectable
5b3sA-3pf2A:
18.65
5b3sJ-3pf2A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_1
(SERINE/THREONINE-PRO
TEIN PHOSPHATASE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
4 / 6 LEU A 256
TRP A 230
PHE A 231
GLU A 332
None
1.12A 5b8iA-3pf2A:
undetectable
5b8iA-3pf2A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_B_ACTB1321_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
3 / 3 THR A 414
ASP A 415
ALA A 416
None
0.00A 5g5gB-3pf2A:
undetectable
5g5gB-3pf2A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
4 / 7 ILE A 236
LEU A 240
THR A 270
LEU A 271
None
0.77A 5iy5A-3pf2A:
undetectable
5iy5J-3pf2A:
undetectable
5iy5A-3pf2A:
18.65
5iy5J-3pf2A:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
4 / 7 ILE A 236
LEU A 240
THR A 270
LEU A 271
None
0.74A 5xdqA-3pf2A:
undetectable
5xdqJ-3pf2A:
undetectable
5xdqA-3pf2A:
18.65
5xdqJ-3pf2A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
4 / 7 ILE A 236
LEU A 240
THR A 270
LEU A 271
None
0.72A 5xdqN-3pf2A:
undetectable
5xdqW-3pf2A:
undetectable
5xdqN-3pf2A:
18.65
5xdqW-3pf2A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
4 / 7 ILE A 236
LEU A 240
THR A 270
LEU A 271
None
0.78A 5xdxA-3pf2A:
undetectable
5xdxJ-3pf2A:
undetectable
5xdxA-3pf2A:
18.65
5xdxJ-3pf2A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
4 / 8 ILE A 236
LEU A 240
THR A 270
LEU A 271
None
0.76A 5xdxN-3pf2A:
undetectable
5xdxW-3pf2A:
undetectable
5xdxN-3pf2A:
18.65
5xdxW-3pf2A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_D_CHDD401_0
(BILE SALT HYDROLASE)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
5 / 10 LEU A 355
ILE A 264
PHE A 294
LEU A 311
LEU A 240
None
1.27A 5y7pD-3pf2A:
undetectable
5y7pD-3pf2A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
4 / 8 ILE A 236
LEU A 240
THR A 270
LEU A 271
None
0.77A 5zcoA-3pf2A:
undetectable
5zcoJ-3pf2A:
undetectable
5zcoA-3pf2A:
18.65
5zcoJ-3pf2A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
4 / 7 ILE A 236
LEU A 240
THR A 270
LEU A 271
None
0.79A 5zcpA-3pf2A:
undetectable
5zcpJ-3pf2A:
undetectable
5zcpA-3pf2A:
18.65
5zcpJ-3pf2A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
4 / 7 ILE A 236
LEU A 240
THR A 270
LEU A 271
None
0.77A 5zcqA-3pf2A:
undetectable
5zcqJ-3pf2A:
undetectable
5zcqA-3pf2A:
18.65
5zcqJ-3pf2A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
4 / 8 ILE A 236
LEU A 240
THR A 270
LEU A 271
None
0.77A 5zcqN-3pf2A:
undetectable
5zcqW-3pf2A:
undetectable
5zcqN-3pf2A:
18.65
5zcqW-3pf2A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
4 / 7 ILE A 236
LEU A 240
THR A 270
LEU A 271
None
0.81A 6nmfA-3pf2A:
undetectable
6nmfJ-3pf2A:
undetectable
6nmfA-3pf2A:
18.65
6nmfJ-3pf2A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3pf2 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae)
4 / 5 ILE A 236
LEU A 240
THR A 270
LEU A 271
None
0.82A 6nmpN-3pf2A:
undetectable
6nmpW-3pf2A:
undetectable
6nmpN-3pf2A:
18.65
6nmpW-3pf2A:
12.09