SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pf7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.96A 1d4fC-3pf7A:
undetectable		 1d4fC-3pf7A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKE_A_HSMA190_1
(NITROPHORIN 4)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		3 / 3 ASP A 363
LEU A 356
LEU A 360
 None
 0.55A 1ikeA-3pf7A:
undetectable		 1ikeA-3pf7A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_B_HSMB304_1
(NITROPHORIN 1)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		3 / 3 ASP A 363
LEU A 356
LEU A 360
 None
 0.57A 1np1B-3pf7A:
undetectable		 1np1B-3pf7A:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OIP_A_VIVA1278_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
LEU A 201
VAL A 436
ILE A 279
ILE A 251
 None
 0.93A 1oipA-3pf7A:
undetectable		 1oipA-3pf7A:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.92A 1v8bA-3pf7A:
undetectable		 1v8bA-3pf7A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.89A 1v8bB-3pf7A:
undetectable		 1v8bB-3pf7A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_C_ADNC2502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.90A 1v8bC-3pf7A:
undetectable		 1v8bC-3pf7A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_D_ADND3502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.91A 1v8bD-3pf7A:
undetectable		 1v8bD-3pf7A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_B_EDTB1511_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		4 / 8 TYR A 299
TRP A 364
ARG A 361
TYR A 292
 None
 1.35A 1zlqB-3pf7A:
undetectable		 1zlqB-3pf7A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1100_1
(SERUM ALBUMIN)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		4 / 6 PHE A 193
TYR A 299
ARG A 212
GLY A 214
 MLA  A1004 (-4.1A)
None
None
MLA  A1004 (-3.2A)
 1.32A 2i30A-3pf7A:
1.2		 2i30A-3pf7A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VPP_A_GEOA1210_1
(DEOXYNUCLEOSIDE
KINASE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 GLU A 150
VAL A 146
GLN A 126
ALA A 122
PHE A 193
 FE  A1001 ( 2.5A)
None
None
None
MLA  A1004 (-4.1A)
 1.25A 2vppA-3pf7A:
0.7		 2vppA-3pf7A:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VPP_B_GEOB1207_1
(DEOXYNUCLEOSIDE
KINASE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 GLU A 150
VAL A 146
GLN A 126
ALA A 122
PHE A 193
 FE  A1001 ( 2.5A)
None
None
None
MLA  A1004 (-4.1A)
 1.29A 2vppB-3pf7A:
undetectable		 2vppB-3pf7A:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.94A 2zj0A-3pf7A:
undetectable		 2zj0A-3pf7A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA608_1
(CHITINASE A)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		4 / 6 TRP A  98
SER A 224
ALA A 230
ASP A 227
 None
 1.37A 3aruA-3pf7A:
undetectable		 3aruA-3pf7A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.96A 3ce6A-3pf7A:
undetectable		 3ce6A-3pf7A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_1
(ADENOSYLHOMOCYSTEINA
SE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.92A 3ce6C-3pf7A:
undetectable		 3ce6C-3pf7A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		4 / 5 ILE A 251
THR A 197
PHE A 290
TYR A 287
 None
 1.18A 3em0A-3pf7A:
undetectable		 3em0A-3pf7A:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_1
(ADENOSYLHOMOCYSTEINA
SE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.96A 3glqA-3pf7A:
undetectable		 3glqA-3pf7A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_1
(ADENOSYLHOMOCYSTEINA
SE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.90A 3glqB-3pf7A:
undetectable		 3glqB-3pf7A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.99A 3n58A-3pf7A:
undetectable		 3n58A-3pf7A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_D_ADND500_1
(ADENOSYLHOMOCYSTEINA
SE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.98A 3n58D-3pf7A:
undetectable		 3n58D-3pf7A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_I_ACHI323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		4 / 8 ILE A 324
GLU A 321
TYR A 311
PHE A  89
 None
 1.06A 3rqwI-3pf7A:
undetectable
3rqwJ-3pf7A:
undetectable		 3rqwI-3pf7A:
21.02
3rqwJ-3pf7A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S79_A_ASDA601_1
(CYTOCHROME P450 19A1)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 ILE A 378
ALA A 252
LEU A 273
MET A 262
LEU A 281
 None
 1.22A 3s79A-3pf7A:
undetectable		 3s79A-3pf7A:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		3 / 3 ASP A 139
GLY A 250
TYR A 138
 None
 0.71A 3w9tC-3pf7A:
undetectable		 3w9tC-3pf7A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		3 / 3 ASP A 139
GLY A 250
TYR A 138
 None
 0.71A 3w9tG-3pf7A:
undetectable		 3w9tG-3pf7A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		4 / 7 ILE A 324
GLU A 321
TYR A 311
PHE A  89
 None
 1.01A 4a97H-3pf7A:
undetectable		 4a97H-3pf7A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FO4_B_MOAB502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		4 / 8 SER A  43
ASN A  42
GLY A 131
MET A  38
 None
 0.83A 4fo4B-3pf7A:
undetectable		 4fo4B-3pf7A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_A_ADNA501_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.91A 4lvcA-3pf7A:
undetectable		 4lvcA-3pf7A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_B_ADNB501_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.93A 4lvcB-3pf7A:
undetectable		 4lvcB-3pf7A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_C_ADNC501_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.89A 4lvcC-3pf7A:
undetectable		 4lvcC-3pf7A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_A_C2FA3000_1
(DIHYDROPTEROATE
SYNTHASE DHPS)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		3 / 3 LYS A  68
ASN A 147
ASP A  47
 None
 0.79A 4o1eA-3pf7A:
undetectable		 4o1eA-3pf7A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.94A 4pfjA-3pf7A:
undetectable		 4pfjA-3pf7A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		4 / 7 THR A 197
LEU A 143
ASN A 147
SER A 181
 None
 1.00A 4pfjA-3pf7A:
undetectable		 4pfjA-3pf7A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.90A 4pgfA-3pf7A:
undetectable		 4pgfA-3pf7A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		4 / 7 ARG A 188
VAL A 158
TRP A  27
GLU A 174
 None
 1.40A 4uh0A-3pf7A:
0.0
4uh0B-3pf7A:
undetectable		 4uh0A-3pf7A:
21.55
4uh0B-3pf7A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		4 / 7 TRP A  27
GLU A 174
ARG A 188
VAL A 158
 None
 1.37A 4uh0A-3pf7A:
0.0
4uh0B-3pf7A:
undetectable		 4uh0A-3pf7A:
21.55
4uh0B-3pf7A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		4 / 6 TRP A  27
GLU A 174
ARG A 188
VAL A 158
 None
 1.38A 5ad7A-3pf7A:
undetectable
5ad7B-3pf7A:
undetectable		 5ad7A-3pf7A:
21.55
5ad7B-3pf7A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		4 / 6 TRP A  27
GLU A 174
ARG A 188
VAL A 158
 None
 1.37A 5ad8A-3pf7A:
undetectable
5ad8B-3pf7A:
undetectable		 5ad8A-3pf7A:
21.55
5ad8B-3pf7A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		4 / 6 TRP A  27
GLU A 174
ARG A 188
VAL A 158
 None
 1.33A 5ad9A-3pf7A:
undetectable
5ad9B-3pf7A:
undetectable		 5ad9A-3pf7A:
21.55
5ad9B-3pf7A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		4 / 7 TRP A  27
GLU A 174
ARG A 188
VAL A 158
 None
 1.35A 5adaA-3pf7A:
undetectable
5adaB-3pf7A:
undetectable		 5adaA-3pf7A:
21.55
5adaB-3pf7A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.89A 5axaA-3pf7A:
undetectable		 5axaA-3pf7A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.91A 5axaC-3pf7A:
undetectable		 5axaC-3pf7A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_B_C2FB402_1
(THYMIDYLATE SYNTHASE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		3 / 3 ASN A 289
ASP A 410
GLY A 411
 None
 0.46A 5fctB-3pf7A:
undetectable		 5fctB-3pf7A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_C_RAPC999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		4 / 8 SER A 293
GLY A 394
THR A 389
PHE A 290
 None
 0.90A 5flcB-3pf7A:
1.8		 5flcB-3pf7A:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_G_RAPG999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		4 / 8 SER A 293
GLY A 394
THR A 389
PHE A 290
 None
 0.90A 5flcF-3pf7A:
1.2		 5flcF-3pf7A:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		4 / 6 TRP A  27
GLU A 174
ARG A 188
VAL A 158
 None
 1.33A 5fvpA-3pf7A:
0.3
5fvpB-3pf7A:
undetectable		 5fvpA-3pf7A:
21.55
5fvpB-3pf7A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.92A 5hm8A-3pf7A:
undetectable		 5hm8A-3pf7A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_B_ADNB501_1
(ADENOSYLHOMOCYSTEINA
SE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.92A 5hm8B-3pf7A:
undetectable		 5hm8B-3pf7A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_C_ADNC501_1
(ADENOSYLHOMOCYSTEINA
SE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.92A 5hm8C-3pf7A:
undetectable		 5hm8C-3pf7A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_D_ADND501_1
(ADENOSYLHOMOCYSTEINA
SE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.92A 5hm8D-3pf7A:
undetectable		 5hm8D-3pf7A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_E_ADNE501_1
(ADENOSYLHOMOCYSTEINA
SE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.93A 5hm8E-3pf7A:
undetectable		 5hm8E-3pf7A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_1
(ADENOSYLHOMOCYSTEINA
SE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.93A 5hm8F-3pf7A:
undetectable		 5hm8F-3pf7A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_G_ADNG501_1
(ADENOSYLHOMOCYSTEINA
SE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.92A 5hm8G-3pf7A:
undetectable		 5hm8G-3pf7A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_H_ADNH501_1
(ADENOSYLHOMOCYSTEINA
SE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.92A 5hm8H-3pf7A:
undetectable		 5hm8H-3pf7A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		3 / 3 VAL A 158
SER A  30
MET A  38
 None
 0.92A 5ikqA-3pf7A:
undetectable		 5ikqA-3pf7A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKV_A_ASDA602_1
(AROMATASE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 ILE A 378
ALA A 252
LEU A 273
MET A 262
LEU A 281
 None
 1.19A 5jkvA-3pf7A:
undetectable		 5jkvA-3pf7A:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8D_A_EDTA609_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		4 / 8 TYR A 299
TRP A 364
ARG A 361
TYR A 292
 None
 1.35A 5l8dA-3pf7A:
0.0		 5l8dA-3pf7A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.93A 5m5kA-3pf7A:
undetectable		 5m5kA-3pf7A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.95A 5m5kB-3pf7A:
undetectable		 5m5kB-3pf7A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.94A 5m5kC-3pf7A:
undetectable		 5m5kC-3pf7A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.89A 5m66A-3pf7A:
undetectable		 5m66A-3pf7A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.91A 5m66B-3pf7A:
undetectable		 5m66B-3pf7A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWU_A_EDTA609_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		4 / 8 TYR A 299
TRP A 364
ARG A 361
TYR A 292
 None
 1.35A 5mwuA-3pf7A:
0.0		 5mwuA-3pf7A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAN_B_REAB503_1
(RETINOIC ACID
RECEPTOR BETA)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 PHE A 386
ILE A 251
ILE A 255
PHE A 388
LEU A 288
 None
 1.47A 5uanB-3pf7A:
undetectable		 5uanB-3pf7A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		4 / 7 ARG A 188
VAL A 158
TRP A  27
GLU A 174
 None
 1.39A 5unuA-3pf7A:
undetectable
5unuB-3pf7A:
undetectable		 5unuA-3pf7A:
21.55
5unuB-3pf7A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		4 / 7 TRP A  27
GLU A 174
ARG A 188
VAL A 158
 None
 1.35A 5unuA-3pf7A:
undetectable
5unuB-3pf7A:
undetectable		 5unuA-3pf7A:
21.55
5unuB-3pf7A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		4 / 7 ARG A 188
VAL A 158
TRP A  27
GLU A 174
 None
 1.37A 5unwA-3pf7A:
undetectable
5unwB-3pf7A:
undetectable		 5unwA-3pf7A:
21.55
5unwB-3pf7A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		4 / 7 TRP A  27
GLU A 174
ARG A 188
VAL A 158
 None
 1.34A 5unwA-3pf7A:
undetectable
5unwB-3pf7A:
undetectable		 5unwA-3pf7A:
21.55
5unwB-3pf7A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		4 / 7 ARG A 188
VAL A 158
TRP A  27
GLU A 174
 None
 1.26A 5unxA-3pf7A:
undetectable
5unxB-3pf7A:
undetectable		 5unxA-3pf7A:
21.55
5unxB-3pf7A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		4 / 6 TRP A  27
GLU A 174
ARG A 188
VAL A 158
 None
 1.28A 5unxA-3pf7A:
undetectable
5unxB-3pf7A:
undetectable		 5unxA-3pf7A:
21.55
5unxB-3pf7A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		4 / 7 TRP A  27
GLU A 174
ARG A 188
VAL A 158
 None
 1.38A 5unyA-3pf7A:
undetectable
5unyB-3pf7A:
undetectable		 5unyA-3pf7A:
21.55
5unyB-3pf7A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		4 / 7 TRP A  27
GLU A 174
ARG A 188
VAL A 158
 None
 1.33A 5uo0A-3pf7A:
undetectable
5uo0B-3pf7A:
undetectable		 5uo0A-3pf7A:
21.55
5uo0B-3pf7A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		4 / 7 ARG A 188
VAL A 158
TRP A  27
GLU A 174
 None
 1.36A 5uo3A-3pf7A:
undetectable
5uo3B-3pf7A:
undetectable		 5uo3A-3pf7A:
21.12
5uo3B-3pf7A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO6_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		4 / 7 TRP A  27
GLU A 174
ARG A 188
VAL A 158
 None
 1.40A 5uo6A-3pf7A:
0.0
5uo6B-3pf7A:
undetectable		 5uo6A-3pf7A:
21.12
5uo6B-3pf7A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		4 / 7 TRP A  27
GLU A 174
ARG A 188
VAL A 158
 None
 1.37A 5uo7A-3pf7A:
undetectable
5uo7B-3pf7A:
undetectable		 5uo7A-3pf7A:
21.12
5uo7B-3pf7A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_F_ADNF503_1
(ADENOSYLHOMOCYSTEINA
SE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.94A 5utuF-3pf7A:
undetectable		 5utuF-3pf7A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_H_ADNH503_1
(ADENOSYLHOMOCYSTEINA
SE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.95A 5utuH-3pf7A:
undetectable		 5utuH-3pf7A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_A_ADNA502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.87A 5v96A-3pf7A:
undetectable		 5v96A-3pf7A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_B_ADNB502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.86A 5v96B-3pf7A:
undetectable		 5v96B-3pf7A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_C_ADNC502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.87A 5v96C-3pf7A:
undetectable		 5v96C-3pf7A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_D_ADND502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.87A 5v96D-3pf7A:
undetectable		 5v96D-3pf7A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_1
(REGULATORY PROTEIN
TETR)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		4 / 8 GLY A 173
ARG A 188
VAL A 114
ASP A 118
 None
 1.04A 5vlmA-3pf7A:
1.0		 5vlmA-3pf7A:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		4 / 7 TRP A  27
GLU A 174
ARG A 188
VAL A 158
 None
 1.35A 5vuiA-3pf7A:
undetectable
5vuiB-3pf7A:
undetectable		 5vuiA-3pf7A:
21.55
5vuiB-3pf7A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		4 / 7 TRP A  27
GLU A 174
ARG A 188
VAL A 158
 None
 1.37A 5vuoA-3pf7A:
undetectable
5vuoB-3pf7A:
undetectable		 5vuoA-3pf7A:
21.55
5vuoB-3pf7A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		4 / 7 TRP A  27
GLU A 174
ARG A 188
VAL A 158
 None
 1.36A 5vusA-3pf7A:
undetectable
5vusB-3pf7A:
undetectable		 5vusA-3pf7A:
21.55
5vusB-3pf7A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		4 / 7 TRP A  27
GLU A 174
ARG A 188
VAL A 158
 None
 1.38A 5vuuA-3pf7A:
undetectable
5vuuB-3pf7A:
undetectable		 5vuuA-3pf7A:
21.55
5vuuB-3pf7A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.88A 6aphA-3pf7A:
undetectable		 6aphA-3pf7A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		4 / 7 TRP A  27
GLU A 174
ARG A 188
VAL A 158
 None
 1.37A 6auxA-3pf7A:
undetectable
6auxB-3pf7A:
undetectable		 6auxA-3pf7A:
10.00
6auxB-3pf7A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		4 / 7 ARG A 188
VAL A 158
TRP A  27
GLU A 174
 None
 1.37A 6av1A-3pf7A:
undetectable
6av1B-3pf7A:
undetectable		 6av1A-3pf7A:
12.47
6av1B-3pf7A:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_1
(-)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.91A 6gbnA-3pf7A:
undetectable		 6gbnA-3pf7A:
24.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_1
(-)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.91A 6gbnB-3pf7A:
undetectable		 6gbnB-3pf7A:
24.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_1
(-)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.91A 6gbnC-3pf7A:
undetectable		 6gbnC-3pf7A:
24.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_D_ADND501_1
(-)		 3pf7 BENZOYL-COA
OXYGENASE COMPONENT
B
(Azoarcus
evansii) 		5 / 12 LEU A 427
HIS A 423
LYS A 398
HIS A 406
PHE A 395
 None
 0.92A 6gbnD-3pf7A:
undetectable		 6gbnD-3pf7A:
24.53