SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pfm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GS4_A_ZK5A1918_1
(ANDROGEN RECEPTOR)		 3pfm GGDEF DOMAIN PROTEIN
(Pseudomonas
protegens) 		5 / 12 LEU A 550
LEU A 553
GLY A 554
ALA A 578
LEU A 577
 None
 1.00A 1gs4A-3pfmA:
undetectable		 1gs4A-3pfmA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI7_A_ID2A1_0
(THYMIDINE KINASE)		 3pfm GGDEF DOMAIN PROTEIN
(Pseudomonas
protegens) 		5 / 12 GLU A 630
ILE A 590
ILE A 587
ALA A 436
ARG A 597
 None
 1.29A 1ki7A-3pfmA:
undetectable		 1ki7A-3pfmA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI7_B_ID2B2_0
(THYMIDINE KINASE)		 3pfm GGDEF DOMAIN PROTEIN
(Pseudomonas
protegens) 		5 / 12 GLU A 630
ILE A 590
ILE A 587
ALA A 436
ARG A 597
 None
 1.17A 1ki7B-3pfmA:
undetectable		 1ki7B-3pfmA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_0
(ESTROGEN RECEPTOR)		 3pfm GGDEF DOMAIN PROTEIN
(Pseudomonas
protegens) 		5 / 12 LEU A 546
LEU A 559
LEU A 577
GLY A 533
LEU A 537
 None
 1.01A 2ouzA-3pfmA:
undetectable		 2ouzA-3pfmA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_1
(ANDROGEN RECEPTOR)		 3pfm GGDEF DOMAIN PROTEIN
(Pseudomonas
protegens) 		5 / 12 LEU A 550
LEU A 553
GLY A 554
ALA A 578
LEU A 577
 None
 0.92A 2oz7A-3pfmA:
undetectable		 2oz7A-3pfmA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3pfm GGDEF DOMAIN PROTEIN
(Pseudomonas
protegens) 		6 / 10 LEU A 500
LEU A 530
LEU A 550
LEU A 546
THR A 504
LEU A 505
 None
 1.47A 4z91A-3pfmA:
undetectable
4z91B-3pfmA:
undetectable
4z91C-3pfmA:
undetectable
4z91D-3pfmA:
undetectable
4z91E-3pfmA:
undetectable		 4z91A-3pfmA:
22.12
4z91B-3pfmA:
22.12
4z91C-3pfmA:
22.12
4z91D-3pfmA:
22.12
4z91E-3pfmA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3pfm GGDEF DOMAIN PROTEIN
(Pseudomonas
protegens) 		6 / 10 LEU A 546
THR A 504
LEU A 505
LEU A 500
LEU A 530
LEU A 550
 None
 1.45A 4z91A-3pfmA:
undetectable
4z91B-3pfmA:
undetectable
4z91C-3pfmA:
undetectable
4z91D-3pfmA:
undetectable
4z91E-3pfmA:
undetectable		 4z91A-3pfmA:
22.12
4z91B-3pfmA:
22.12
4z91C-3pfmA:
22.12
4z91D-3pfmA:
22.12
4z91E-3pfmA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3pfm GGDEF DOMAIN PROTEIN
(Pseudomonas
protegens) 		4 / 4 ALA A 616
PRO A 432
LEU A 496
HIS A 444
 None
 1.28A 5eskA-3pfmA:
undetectable		 5eskA-3pfmA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_E_ASCE1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 3pfm GGDEF DOMAIN PROTEIN
(Pseudomonas
protegens) 		4 / 7 HIS A 444
ILE A 615
VAL A 636
GLN A 431
 None
 1.24A 5kkzC-3pfmA:
undetectable
5kkzE-3pfmA:
undetectable		 5kkzC-3pfmA:
21.65
5kkzE-3pfmA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_K_ASCK1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 3pfm GGDEF DOMAIN PROTEIN
(Pseudomonas
protegens) 		4 / 7 ILE A 615
VAL A 636
GLN A 431
HIS A 444
 None
 1.20A 5kkzK-3pfmA:
undetectable
5kkzQ-3pfmA:
undetectable		 5kkzK-3pfmA:
20.27
5kkzQ-3pfmA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGJ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3pfm GGDEF DOMAIN PROTEIN
(Pseudomonas
protegens) 		3 / 3 VAL A 442
VAL A 434
GLN A 431
 None
 0.63A 5qgjA-3pfmA:
undetectable		 5qgjA-3pfmA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGM_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3pfm GGDEF DOMAIN PROTEIN
(Pseudomonas
protegens) 		3 / 3 VAL A 442
VAL A 434
GLN A 431
 None
 0.65A 5qgmA-3pfmA:
undetectable		 5qgmA-3pfmA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGN_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3pfm GGDEF DOMAIN PROTEIN
(Pseudomonas
protegens) 		3 / 3 VAL A 442
VAL A 434
GLN A 431
 None
 0.59A 5qgnA-3pfmA:
undetectable		 5qgnA-3pfmA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGY_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3pfm GGDEF DOMAIN PROTEIN
(Pseudomonas
protegens) 		3 / 3 VAL A 442
VAL A 434
GLN A 431
 None
 0.67A 5qgyA-3pfmA:
undetectable		 5qgyA-3pfmA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGZ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3pfm GGDEF DOMAIN PROTEIN
(Pseudomonas
protegens) 		3 / 3 VAL A 442
VAL A 434
GLN A 431
 None
 0.67A 5qgzA-3pfmA:
undetectable		 5qgzA-3pfmA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH2_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3pfm GGDEF DOMAIN PROTEIN
(Pseudomonas
protegens) 		3 / 3 VAL A 442
VAL A 434
GLN A 431
 None
 0.67A 5qh2A-3pfmA:
undetectable		 5qh2A-3pfmA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH3_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3pfm GGDEF DOMAIN PROTEIN
(Pseudomonas
protegens) 		3 / 3 VAL A 442
VAL A 434
GLN A 431
 None
 0.67A 5qh3A-3pfmA:
undetectable		 5qh3A-3pfmA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3pfm GGDEF DOMAIN PROTEIN
(Pseudomonas
protegens) 		3 / 3 VAL A 442
VAL A 434
GLN A 431
 None
 0.62A 5qh5A-3pfmA:
undetectable		 5qh5A-3pfmA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3pfm GGDEF DOMAIN PROTEIN
(Pseudomonas
protegens) 		3 / 3 VAL A 442
VAL A 434
GLN A 431
 None
 0.63A 5qh6A-3pfmA:
undetectable		 5qh6A-3pfmA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH7_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3pfm GGDEF DOMAIN PROTEIN
(Pseudomonas
protegens) 		3 / 3 VAL A 442
VAL A 434
GLN A 431
 None
 0.66A 5qh7A-3pfmA:
undetectable		 5qh7A-3pfmA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3pfm GGDEF DOMAIN PROTEIN
(Pseudomonas
protegens) 		3 / 3 VAL A 442
VAL A 434
GLN A 431
 None
 0.68A 5qhhA-3pfmA:
undetectable		 5qhhA-3pfmA:
20.08