SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pfn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Y0X_X_T44X500_1 (THYROID HORMONE RECEPTOR BETA-1)	3pfn	NAD KINASE (Homo sapiens)	5 / 12	ALA A 232 ARG A 97 MET A 202 MET A 134 PHE A 177	None	1.45A	1y0xX-3pfnA: undetectable	1y0xX-3pfnA: 20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y05_A_RALA802_1 (PROSTAGLANDIN REDUCTASE 1)	3pfn	NAD KINASE (Homo sapiens)	4 / 7	VAL A 242 TYR A 280 GLY A 384 VAL A 380	None	0.96A	2y05A-3pfnA: undetectable 2y05B-3pfnA: 4.0	2y05A-3pfnA: 23.12 2y05B-3pfnA: 23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GAN_A_SVRA158_1 (UNCHARACTERIZED PROTEIN AT3G22680)	3pfn	NAD KINASE (Homo sapiens)	5 / 11	VAL A 360 PRO A 361 TYR A 327 ILE A 317 ILE A 368	None None None UNX A 8 ( 4.3A) None	1.47A	3ganA-3pfnA: undetectable	3ganA-3pfnA: 19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JW1_B_CELB602_2 (PROSTAGLANDIN G/H SYNTHASE 2)	3pfn	NAD KINASE (Homo sapiens)	4 / 6	VAL A 157 VAL A 109 ILE A 171 PHE A 164	None	1.06A	5jw1B-3pfnA: undetectable	5jw1B-3pfnA: 20.86

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1Y0X_X_T44X500_1","THYROID HORMONE RECEPTOR BETA-1","3pfn","NAD KINASE","Homo sapiens",5,"ALA A 232;ARG A  97;MET A 202;MET A 134;PHE A 177","None","1.45A","1y0xX-3pfnA:undetectable","1y0xX-3pfnA:20.06"],["2Y05_A_RALA802_1","PROSTAGLANDIN REDUCTASE 1;PROSTAGLANDIN REDUCTASE 1","3pfn","NAD KINASE","Homo sapiens",4,"VAL A 242;TYR A 280;GLY A 384;VAL A 380","None","0.96A","2y05A-3pfnA:undetectable;2y05B-3pfnA:4.0","2y05A-3pfnA:23.12;2y05B-3pfnA:23.12"],["3GAN_A_SVRA158_1","UNCHARACTERIZED PROTEIN AT3G22680","3pfn","NAD KINASE","Homo sapiens",5,"VAL A 360;PRO A 361;TYR A 327;ILE A 317;ILE A 368","None;None;None;UNX A   8 ( 4.3A);None","1.47A","3ganA-3pfnA:undetectable","3ganA-3pfnA:19.21"],["5JW1_B_CELB602_2","PROSTAGLANDIN G\/H SYNTHASE 2","3pfn","NAD KINASE","Homo sapiens",4,"VAL A 157;VAL A 109;ILE A 171;PHE A 164","None","1.06A","5jw1B-3pfnA:undetectable","5jw1B-3pfnA:20.86"]]