SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pfs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_0
(ALCOHOL
DEHYDROGENASE)		 3pfs BROMODOMAIN AND PHD
FINGER-CONTAINING
PROTEIN 3
(Homo
sapiens) 		3 / 3 MET A1187
LEU A1190
SER A1191
 None
 0.63A 1ee2A-3pfsA:
undetectable		 1ee2A-3pfsA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_A_HSMA303_1
(NITROPHORIN 1)		 3pfs BROMODOMAIN AND PHD
FINGER-CONTAINING
PROTEIN 3
(Homo
sapiens) 		4 / 5 ASP A1163
GLU A1159
LEU A1154
LEU A1156
 None
 1.09A 1np1A-3pfsA:
undetectable		 1np1A-3pfsA:
22.51