SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pft'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2002_1
(SERUM ALBUMIN)		 3pft FLAVIN REDUCTASE
(Mycolicibacteriu
m
goodii) 		5 / 10 ALA A  26
ALA A  24
LEU A  76
LEU A  87
ALA A  83
 None
 1.18A 2bxeA-3pftA:
undetectable		 2bxeA-3pftA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_0
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 3pft FLAVIN REDUCTASE
(Mycolicibacteriu
m
goodii) 		5 / 12 PHE A  53
ILE A  73
ALA A  38
LEU A  71
LEU A 124
 None
None
FMN  A 401 (-3.5A)
None
None
 1.11A 2rctA-3pftA:
undetectable		 2rctA-3pftA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFG_B_LEUB289_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 3pft FLAVIN REDUCTASE
(Mycolicibacteriu
m
goodii) 		3 / 3 PHE A 109
SER A 105
SER A  70
 None
 0.91A 3ufgB-3pftA:
undetectable		 3ufgB-3pftA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 3pft FLAVIN REDUCTASE
(Mycolicibacteriu
m
goodii) 		3 / 3 PRO A  63
VAL A  55
HIS A 130
 None
FMN  A 401 (-3.6A)
None
 0.81A 4pevC-3pftA:
undetectable		 4pevC-3pftA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 3pft FLAVIN REDUCTASE
(Mycolicibacteriu
m
goodii) 		5 / 12 PHE A  53
ILE A  73
ALA A  38
LEU A  71
LEU A 124
 None
None
FMN  A 401 (-3.5A)
None
None
 1.06A 4qynA-3pftA:
undetectable		 4qynA-3pftA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)		 3pft FLAVIN REDUCTASE
(Mycolicibacteriu
m
goodii) 		5 / 12 PHE A  53
ILE A  73
ALA A  38
LEU A  71
LEU A 124
 None
None
FMN  A 401 (-3.5A)
None
None
 1.04A 4qzuC-3pftA:
undetectable		 4qzuC-3pftA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_B_CL6B502_1
(CYTOCHROME P-450)		 3pft FLAVIN REDUCTASE
(Mycolicibacteriu
m
goodii) 		4 / 5 LEU A  98
ALA A  26
VAL A  22
ILE A  23
 None
 0.89A 4xe3B-3pftA:
undetectable		 4xe3B-3pftA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 3pft FLAVIN REDUCTASE
(Mycolicibacteriu
m
goodii) 		4 / 5 VAL A 133
THR A 131
LEU A  71
VAL A  34
 None
 0.92A 6bqgA-3pftA:
undetectable		 6bqgA-3pftA:
19.11