SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pg5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_B_NOVB444_2
(DNA GYRASE SUBUNIT B)		 3pg5 UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		3 / 3 ASP A 177
PHE A 350
VAL A 156
 None
 0.52A 1kijB-3pg5A:
undetectable		 1kijB-3pg5A:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_G_AG2G7003_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 3pg5 UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		4 / 6 LEU A 349
ASP A 177
GLY A 175
ARG A 233
 None
 0.87A 1mt1G-3pg5A:
undetectable
1mt1J-3pg5A:
undetectable		 1mt1G-3pg5A:
11.35
1mt1J-3pg5A:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_K_AG2K7002_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 3pg5 UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		4 / 7 ARG A 233
LEU A 349
ASP A 177
GLY A 175
 None
 0.89A 1mt1H-3pg5A:
undetectable
1mt1K-3pg5A:
undetectable		 1mt1H-3pg5A:
16.43
1mt1K-3pg5A:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_D_AG2D7015_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 3pg5 UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		4 / 7 ARG A 233
LEU A 349
ASP A 177
GLY A 175
 None
 0.89A 1n13D-3pg5A:
undetectable
1n13E-3pg5A:
undetectable		 1n13D-3pg5A:
16.43
1n13E-3pg5A:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_F_AG2F7016_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 3pg5 UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		4 / 8 LEU A 349
ASP A 177
GLY A 175
ARG A 233
 None
 0.91A 1n13A-3pg5A:
undetectable
1n13F-3pg5A:
undetectable		 1n13A-3pg5A:
11.35
1n13F-3pg5A:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_H_AG2H7012_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 3pg5 UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		4 / 6 ARG A 233
LEU A 349
ASP A 177
GLY A 175
 None
 0.91A 1n13H-3pg5A:
undetectable
1n13K-3pg5A:
undetectable		 1n13H-3pg5A:
16.43
1n13K-3pg5A:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_J_AG2J7013_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 3pg5 UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		4 / 7 LEU A 349
ASP A 177
GLY A 175
ARG A 233
 None
 0.91A 1n13G-3pg5A:
undetectable
1n13J-3pg5A:
undetectable		 1n13G-3pg5A:
11.35
1n13J-3pg5A:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RI4_A_SAMA299_0
(MRNA CAPPING ENZYME)		 3pg5 UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		5 / 12 GLY A 175
ILE A 157
ALA A 145
PHE A 179
SER A   5
 None
 1.10A 1ri4A-3pg5A:
undetectable		 1ri4A-3pg5A:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RU9_H_ACTH611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 3pg5 UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		4 / 6 TRP A 199
ASN A   9
LEU A 196
PHE A   7
 None
 1.09A 1ru9H-3pg5A:
undetectable
1ru9L-3pg5A:
undetectable		 1ru9H-3pg5A:
21.29
1ru9L-3pg5A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_L_ACTL611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 3pg5 UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		4 / 6 TRP A 199
ASN A   9
LEU A 196
PHE A   7
 None
 1.10A 1rukH-3pg5A:
undetectable
1rukL-3pg5A:
undetectable		 1rukH-3pg5A:
21.29
1rukL-3pg5A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_A_SAMA301_1
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 3pg5 UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		3 / 3 GLY A 162
ASP A  39
ASN A   8
 None
 0.65A 1vq1A-3pg5A:
undetectable		 1vq1A-3pg5A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 3pg5 UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		3 / 3 THR A  75
PRO A 111
TYR A  58
 None
 0.86A 2dxrA-3pg5A:
undetectable		 2dxrA-3pg5A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_K_AG2K671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3pg5 UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		4 / 8 ARG A 233
LEU A 349
ASP A 177
GLY A 175
 None
 0.91A 2qqcH-3pg5A:
undetectable
2qqcK-3pg5A:
undetectable		 2qqcH-3pg5A:
17.15
2qqcK-3pg5A:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_2
(AAC(6')-IB)		 3pg5 UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		3 / 3 TRP A 199
GLN A 206
TRP A 140
 None
 1.36A 2vqyA-3pg5A:
undetectable		 2vqyA-3pg5A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1413_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 3pg5 UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		4 / 6 ALA A 147
ALA A 145
THR A   3
PHE A 159
 None
 1.06A 2xfhA-3pg5A:
undetectable		 2xfhA-3pg5A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA1_A_08YA600_1
(CYTOCHROME P450 3A4)		 3pg5 UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		5 / 12 SER A 284
ILE A 281
THR A   3
ALA A 202
ALA A 208
 None
 1.37A 3ua1A-3pg5A:
undetectable		 3ua1A-3pg5A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJE_B_C2FB302_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3pg5 UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		5 / 12 GLU A 117
ASP A 160
GLY A 162
SER A 164
ASN A 169
 None
 1.37A 4djeB-3pg5A:
undetectable		 4djeB-3pg5A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 3pg5 UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		5 / 12 TYR A 207
GLY A 236
GLY A 241
ALA A 145
HIS A 139
 None
 0.99A 4krhB-3pg5A:
2.0		 4krhB-3pg5A:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4H_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 3pg5 UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		4 / 5 ASP A 186
ALA A 192
LYS A  10
THR A 183
 None
 1.16A 4z4hA-3pg5A:
2.6		 4z4hA-3pg5A:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3pg5 UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		4 / 6 ASP A 186
ALA A 192
LYS A  10
THR A 183
 None
 1.16A 4z4iA-3pg5A:
3.7		 4z4iA-3pg5A:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_A_GCSA407_1
(PREDICTED
ACETYLTRANSFERASE)		 3pg5 UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		4 / 8 PRO A  40
GLY A 162
PRO A 163
ASP A  39
 None
 1.10A 5kgpA-3pg5A:
undetectable		 5kgpA-3pg5A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_B_GCSB405_1
(PREDICTED
ACETYLTRANSFERASE)		 3pg5 UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		4 / 8 PRO A  40
GLY A 162
PRO A 163
ASP A  39
 None
 1.09A 5kgpB-3pg5A:
undetectable		 5kgpB-3pg5A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 3pg5 UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		5 / 12 GLY A  14
GLY A  12
THR A  16
ALA A 184
LEU A 250
 None
 0.88A 5kpcA-3pg5A:
undetectable		 5kpcA-3pg5A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_A_ACTA701_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 3pg5 UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		3 / 3 LYS A 228
LYS A 219
SER A 222
 None
 1.42A 5odiA-3pg5A:
undetectable		 5odiA-3pg5A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3pg5 UNCHARACTERIZED
PROTEIN
(Corynebacterium
diphtheriae) 		3 / 3 ARG A 233
PHE A 158
PHE A 237
 None
 0.97A 6nknC-3pg5A:
undetectable
6nknJ-3pg5A:
undetectable		 6nknC-3pg5A:
18.41
6nknJ-3pg5A:
11.24