SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pg6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H9Z_A_RWFA3001_1
(SERUM ALBUMIN)		 3pg6 E3 UBIQUITIN-PROTEIN
LIGASE DTX3L
(Homo
sapiens) 		5 / 11 ALA A 662
LEU A 664
HIS A 707
ARG A 729
SER A 725
 None
 1.14A 1h9zA-3pg6A:
undetectable		 1h9zA-3pg6A:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 3pg6 E3 UBIQUITIN-PROTEIN
LIGASE DTX3L
(Homo
sapiens) 		5 / 12 LEU A 727
VAL A 673
ILE A 635
LEU A 677
GLU A 733
 None
 1.12A 4y0qA-3pg6A:
undetectable		 4y0qA-3pg6A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KI6_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 3pg6 E3 UBIQUITIN-PROTEIN
LIGASE DTX3L
(Homo
sapiens) 		4 / 5 LEU A 664
LYS A 709
LEU A 727
TYR A 726
 None
 1.45A 5ki6A-3pg6A:
undetectable		 5ki6A-3pg6A:
11.58