SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pgy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_A_FFOA1002_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	4 / 5	GLU A 53 TYR A 51 PHE A 251 PRO A 252	None	1.02A	1dfoB-3pgyA: 57.3	1dfoB-3pgyA: 58.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_B_FFOB2002_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	4 / 5	GLU A 53 TYR A 51 PHE A 251 PRO A 252	None	1.02A	1dfoA-3pgyA: 56.4	1dfoA-3pgyA: 58.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_C_FFOC3002_2 (SERINE HYDROXYMETHYLTRANSFE RASE)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	4 / 5	GLU A 53 TYR A 51 PHE A 251 PRO A 252	None	1.02A	1dfoD-3pgyA: 56.5	1dfoD-3pgyA: 58.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_D_FFOD4002_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	4 / 5	GLU A 53 TYR A 51 PHE A 251 PRO A 252	None	1.02A	1dfoC-3pgyA: 57.3	1dfoC-3pgyA: 58.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IE4_B_T44B328_1 (TRANSTHYRETIN)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	5 / 8	GLU A 41 LEU A 47 GLU A 272 ALA A 267 THR A 70	None	1.23A	1ie4B-3pgyA: undetectable 1ie4D-3pgyA: undetectable	1ie4B-3pgyA: 14.22 1ie4D-3pgyA: 14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q23_C_FUAC701_1 (CHLORAMPHENICOL ACETYLTRANSFERASE)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	4 / 4	ALA A 42 VAL A 268 ALA A 265 HIS A 261	None	1.14A	1q23A-3pgyA: undetectable	1q23A-3pgyA: 19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2GJ5_A_VD3A163_1 (BETA-LACTOGLOBULIN)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	5 / 12	ILE A 26 LEU A 28 ILE A 337 ILE A 380 ALA A 384	None	1.24A	2gj5A-3pgyA: undetectable	2gj5A-3pgyA: 16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OBV_A_SAMA501_0 (S-ADENOSYLMETHIONINE SYNTHETASE ISOFORM TYPE-1)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	4 / 8	HIS A 210 PRO A 211 SER A 175 SER A 305	None	1.18A	2obvA-3pgyA: undetectable	2obvA-3pgyA: 21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2P02_A_SAMA2_0 (S-ADENOSYLMETHIONINE SYNTHETASE ISOFORM TYPE-2)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	4 / 8	HIS A 210 PRO A 211 SER A 175 SER A 305	None	1.24A	2p02A-3pgyA: undetectable	2p02A-3pgyA: 22.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2VMY_A_FFOA505_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	4 / 6	GLU A 53 TYR A 51 PHE A 251 PRO A 252	None	1.19A	2vmyA-3pgyA: 58.8	2vmyA-3pgyA: 71.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W9G_A_TOPA1159_1 (DIHYDROFOLATE REDUCTASE)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	5 / 10	ALA A 364 LEU A 28 LEU A 292 ILE A 380 THR A 365	None	1.09A	2w9gA-3pgyA: undetectable	2w9gA-3pgyA: 18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W9H_A_TOPA1160_1 (DIHYDROFOLATE REDUCTASE)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	5 / 10	ALA A 364 LEU A 28 LEU A 292 ILE A 380 THR A 365	None	0.98A	2w9hA-3pgyA: 2.2	2w9hA-3pgyA: 18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XH9_B_J01B1436_1 (ORF12)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	5 / 9	VAL A 304 ILE A 344 LEU A 385 GLY A 325 ALA A 328	None	1.41A	2xh9B-3pgyA: undetectable	2xh9B-3pgyA: 22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Z54_A_AB1A200_1 (HIV-1 PROTEASE)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	5 / 12	GLY A 208 ALA A 207 ILE A 201 PRO A 362 VAL A 285	None	1.05A	2z54A-3pgyA: undetectable	2z54A-3pgyA: 12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A2Q_A_ACAA602_1 (6-AMINOHEXANOATE-CYC LIC-DIMER HYDROLASE)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	4 / 7	ASN A 88 ALA A 74 ALA A 78 GLN A 90	None	0.69A	3a2qA-3pgyA: undetectable	3a2qA-3pgyA: 22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EKT_B_017B200_2 (PROTEASE)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	5 / 9	ASP A 316 VAL A 315 GLY A 300 ALA A 293 ILE A 303	None	1.08A	3ektB-3pgyA: undetectable	3ektB-3pgyA: 13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FL9_B_TOPB200_1 (DIHYDROFOLATE REDUCTASE (DHFR))	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	5 / 12	ALA A 364 LEU A 28 LEU A 292 ILE A 380 THR A 365	None	1.07A	3fl9B-3pgyA: undetectable	3fl9B-3pgyA: 16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FL9_E_TOPE200_1 (DIHYDROFOLATE REDUCTASE (DHFR))	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	5 / 10	ALA A 364 LEU A 28 LEU A 292 ILE A 380 THR A 365	None	0.91A	3fl9E-3pgyA: undetectable	3fl9E-3pgyA: 16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FL9_G_TOPG200_1 (DIHYDROFOLATE REDUCTASE (DHFR))	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	5 / 12	ALA A 364 LEU A 28 LEU A 292 ILE A 380 THR A 365	None	1.09A	3fl9G-3pgyA: undetectable	3fl9G-3pgyA: 16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KW2_A_ADNA300_1 (PROBABLE R-RNA METHYLTRANSFERASE)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	5 / 11	ILE A 357 ASP A 316 LEU A 385 LEU A 323 ALA A 328	None	1.08A	3kw2A-3pgyA: undetectable	3kw2A-3pgyA: 20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KW2_A_ADNA300_1 (PROBABLE R-RNA METHYLTRANSFERASE)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	5 / 11	ILE A 357 GLY A 356 ASP A 316 LEU A 385 ALA A 328	None	1.14A	3kw2A-3pgyA: undetectable	3kw2A-3pgyA: 20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KW2_B_ADNB300_1 (PROBABLE R-RNA METHYLTRANSFERASE)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	5 / 11	ILE A 357 ASP A 316 LEU A 385 LEU A 323 ALA A 328	None	1.08A	3kw2B-3pgyA: undetectable	3kw2B-3pgyA: 20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KW2_B_ADNB300_1 (PROBABLE R-RNA METHYLTRANSFERASE)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	5 / 11	ILE A 357 GLY A 356 ASP A 316 LEU A 385 ALA A 328	None	1.17A	3kw2B-3pgyA: undetectable	3kw2B-3pgyA: 20.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3PGY_A_GLYA510_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	5 / 6	GLU A 27 ILE A 29 GLU A 32 PHE A 34 ALA A 363	GLY A 510 (-2.8A) None None GLY A 510 (-4.0A) GLY A 510 (-2.9A)	0.42A	3pgyA-3pgyA: 71.3 3pgyB-3pgyA: 66.2	3pgyA-3pgyA: 100.00 3pgyB-3pgyA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3PGY_B_GLYB509_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	4 / 4	PHE A 34 THR A 366 LEU A 410 TYR A 411	GLY A 510 (-4.0A) None None None	0.18A	3pgyB-3pgyA: 66.2	3pgyB-3pgyA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3PGY_B_GLYB511_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	4 / 5	SER A 334 GLU A 391 LEU A 394 LYS A 398	None	0.59A	3pgyB-3pgyA: 66.2	3pgyB-3pgyA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3PGY_B_GLYB511_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	4 / 5	SER A 334 LEU A 394 GLN A 395 LYS A 398	None	0.89A	3pgyB-3pgyA: 66.2	3pgyB-3pgyA: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VNS_A_DVAA602_0 (NRPS ADENYLATION PROTEIN CYTC1)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	4 / 7	PHE A 180 PHE A 183 GLY A 170 THR A 177	None	1.07A	3vnsA-3pgyA: undetectable	3vnsA-3pgyA: 23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FIA_A_0U9A601_1 (CHOLESTEROL 24-HYDROXYLASE)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	5 / 12	PHE A 82 ALA A 202 THR A 227 GLU A 272 ALA A 273	None	1.18A	4fiaA-3pgyA: undetectable	4fiaA-3pgyA: 23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FIA_A_198A602_1 (CHOLESTEROL 24-HYDROXYLASE)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	5 / 12	PHE A 82 ALA A 202 THR A 227 GLU A 272 ALA A 273	None	1.18A	4fiaA-3pgyA: undetectable	4fiaA-3pgyA: 23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J14_A_X2NA602_1 (CHOLESTEROL 24-HYDROXYLASE)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	5 / 10	ALA A 295 LEU A 296 PHE A 301 VAL A 315 ILE A 321	None	1.05A	4j14A-3pgyA: undetectable	4j14A-3pgyA: 23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KTT_C_SAMC404_0 (S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	4 / 8	HIS A 210 PRO A 211 SER A 175 SER A 305	None	1.15A	4kttC-3pgyA: undetectable	4kttC-3pgyA: 22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PCL_B_SAMB301_0 (O-METHYLTRANSFERASE FAMILY PROTEIN)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	5 / 12	GLN A 90 LEU A 259 GLY A 234 ALA A 199 ASN A 98	None	1.28A	4pclB-3pgyA: 3.7	4pclB-3pgyA: 21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVP_B_BO2B201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	5 / 11	HIS A 200 SER A 31 THR A 223 THR A 222 GLY A 230	None	1.46A	4qvpV-3pgyA: undetectable 4qvpb-3pgyA: undetectable	4qvpV-3pgyA: 21.27 4qvpb-3pgyA: 20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVP_N_BO2N201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	5 / 11	HIS A 200 SER A 31 THR A 223 THR A 222 GLY A 230	None	1.45A	4qvpH-3pgyA: undetectable 4qvpN-3pgyA: undetectable	4qvpH-3pgyA: 21.27 4qvpN-3pgyA: 20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVQ_B_BO2B201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	5 / 11	HIS A 200 SER A 31 THR A 223 THR A 222 GLY A 230	None	1.46A	4qvqV-3pgyA: undetectable 4qvqb-3pgyA: undetectable	4qvqV-3pgyA: 21.27 4qvqb-3pgyA: 20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVQ_N_BO2N201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	5 / 11	HIS A 200 SER A 31 THR A 223 THR A 222 GLY A 230	None	1.46A	4qvqH-3pgyA: undetectable 4qvqN-3pgyA: undetectable	4qvqH-3pgyA: 21.27 4qvqN-3pgyA: 20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QWU_B_BO2B201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	5 / 11	HIS A 200 SER A 31 THR A 223 THR A 222 GLY A 230	None	1.44A	4qwuV-3pgyA: undetectable 4qwub-3pgyA: undetectable	4qwuV-3pgyA: 21.27 4qwub-3pgyA: 20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QWU_N_BO2N201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	5 / 11	HIS A 200 SER A 31 THR A 223 THR A 222 GLY A 230	None	1.44A	4qwuH-3pgyA: undetectable 4qwuN-3pgyA: undetectable	4qwuH-3pgyA: 21.27 4qwuN-3pgyA: 20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4R1Z_B_AERB601_1 (CYP17A1 PROTEIN)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	4 / 7	ALA A 273 SER A 31 ALA A 202 THR A 222	None	0.86A	4r1zB-3pgyA: 2.1	4r1zB-3pgyA: 24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UBE_A_2FAA401_2 (ADENOSINE KINASE)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	4 / 4	ALA A 267 VAL A 89 GLY A 234 THR A 224	None	1.14A	4ubeA-3pgyA: 3.8	4ubeA-3pgyA: 23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E4D_B_BEZB203_0 (HYDROXYNITRILE LYASE)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	4 / 4	VAL A 268 ALA A 264 ILE A 73 THR A 70	None	1.06A	5e4dB-3pgyA: undetectable	5e4dB-3pgyA: 18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FBN_B_SAMB401_1 (S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	4 / 8	HIS A 210 PRO A 211 SER A 175 SER A 305	None	1.14A	6fbnB-3pgyA: undetectable	6fbnB-3pgyA: 22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FCB_A_SAMA405_0 (S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2)	3pgy	SERINE HYDROXYMETHYLTRANSFE RASE (Staphylococcus aureus)	4 / 8	HIS A 210 PRO A 211 SER A 175 SER A 305	None	1.18A	6fcbA-3pgyA: undetectable	6fcbA-3pgyA: 22.84

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DFO_A_FFOA1002_1","SERINE HYDROXYMETHYLTRANSFERASE","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",4,"GLU A  53;TYR A  51;PHE A 251;PRO A 252","None","1.02A","1dfoB-3pgyA:57.3","1dfoB-3pgyA:58.47"],["1DFO_B_FFOB2002_0","SERINE HYDROXYMETHYLTRANSFERASE","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",4,"GLU A  53;TYR A  51;PHE A 251;PRO A 252","None","1.02A","1dfoA-3pgyA:56.4","1dfoA-3pgyA:58.47"],["1DFO_C_FFOC3002_2","SERINE HYDROXYMETHYLTRANSFERASE","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",4,"GLU A  53;TYR A  51;PHE A 251;PRO A 252","None","1.02A","1dfoD-3pgyA:56.5","1dfoD-3pgyA:58.47"],["1DFO_D_FFOD4002_0","SERINE HYDROXYMETHYLTRANSFERASE","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",4,"GLU A  53;TYR A  51;PHE A 251;PRO A 252","None","1.02A","1dfoC-3pgyA:57.3","1dfoC-3pgyA:58.47"],["1IE4_B_T44B328_1","TRANSTHYRETIN;TRANSTHYRETIN","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",5,"GLU A  41;LEU A  47;GLU A 272;ALA A 267;THR A  70","None","1.23A","1ie4B-3pgyA:undetectable;1ie4D-3pgyA:undetectable","1ie4B-3pgyA:14.22;1ie4D-3pgyA:14.22"],["1Q23_C_FUAC701_1","CHLORAMPHENICOL ACETYLTRANSFERASE;CHLORAMPHENICOL ACETYLTRANSFERASE","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",4,"ALA A  42;VAL A 268;ALA A 265;HIS A 261","None","1.14A","1q23A-3pgyA:undetectable","1q23A-3pgyA:19.41"],["2GJ5_A_VD3A163_1","BETA-LACTOGLOBULIN","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",5,"ILE A  26;LEU A  28;ILE A 337;ILE A 380;ALA A 384","None","1.24A","2gj5A-3pgyA:undetectable","2gj5A-3pgyA:16.45"],["2OBV_A_SAMA501_0","S-ADENOSYLMETHIONINE SYNTHETASE ISOFORM TYPE-1","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",4,"HIS A 210;PRO A 211;SER A 175;SER A 305","None","1.18A","2obvA-3pgyA:undetectable","2obvA-3pgyA:21.27"],["2P02_A_SAMA2_0","S-ADENOSYLMETHIONINE SYNTHETASE ISOFORM TYPE-2","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",4,"HIS A 210;PRO A 211;SER A 175;SER A 305","None","1.24A","2p02A-3pgyA:undetectable","2p02A-3pgyA:22.52"],["2VMY_A_FFOA505_0","SERINE HYDROXYMETHYLTRANSFERASE","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",4,"GLU A  53;TYR A  51;PHE A 251;PRO A 252","None","1.19A","2vmyA-3pgyA:58.8","2vmyA-3pgyA:71.67"],["2W9G_A_TOPA1159_1","DIHYDROFOLATE REDUCTASE","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",5,"ALA A 364;LEU A  28;LEU A 292;ILE A 380;THR A 365","None","1.09A","2w9gA-3pgyA:undetectable","2w9gA-3pgyA:18.97"],["2W9H_A_TOPA1160_1","DIHYDROFOLATE REDUCTASE","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",5,"ALA A 364;LEU A  28;LEU A 292;ILE A 380;THR A 365","None","0.98A","2w9hA-3pgyA:2.2","2w9hA-3pgyA:18.97"],["2XH9_B_J01B1436_1","ORF12","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",5,"VAL A 304;ILE A 344;LEU A 385;GLY A 325;ALA A 328","None","1.41A","2xh9B-3pgyA:undetectable","2xh9B-3pgyA:22.75"],["2Z54_A_AB1A200_1","HIV-1 PROTEASE","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",5,"GLY A 208;ALA A 207;ILE A 201;PRO A 362;VAL A 285","None","1.05A","2z54A-3pgyA:undetectable","2z54A-3pgyA:12.53"],["3A2Q_A_ACAA602_1","6-AMINOHEXANOATE-CYCLIC-DIMER HYDROLASE","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",4,"ASN A  88;ALA A  74;ALA A  78;GLN A  90","None","0.69A","3a2qA-3pgyA:undetectable","3a2qA-3pgyA:22.52"],["3EKT_B_017B200_2","PROTEASE","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",5,"ASP A 316;VAL A 315;GLY A 300;ALA A 293;ILE A 303","None","1.08A","3ektB-3pgyA:undetectable","3ektB-3pgyA:13.46"],["3FL9_B_TOPB200_1","DIHYDROFOLATE REDUCTASE (DHFR)","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",5,"ALA A 364;LEU A  28;LEU A 292;ILE A 380;THR A 365","None","1.07A","3fl9B-3pgyA:undetectable","3fl9B-3pgyA:16.75"],["3FL9_E_TOPE200_1","DIHYDROFOLATE REDUCTASE (DHFR)","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",5,"ALA A 364;LEU A  28;LEU A 292;ILE A 380;THR A 365","None","0.91A","3fl9E-3pgyA:undetectable","3fl9E-3pgyA:16.75"],["3FL9_G_TOPG200_1","DIHYDROFOLATE REDUCTASE (DHFR)","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",5,"ALA A 364;LEU A  28;LEU A 292;ILE A 380;THR A 365","None","1.09A","3fl9G-3pgyA:undetectable","3fl9G-3pgyA:16.75"],["3KW2_A_ADNA300_1","PROBABLE R-RNA METHYLTRANSFERASE","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",5,"ILE A 357;ASP A 316;LEU A 385;LEU A 323;ALA A 328","None","1.08A","3kw2A-3pgyA:undetectable","3kw2A-3pgyA:20.67"],["3KW2_A_ADNA300_1","PROBABLE R-RNA METHYLTRANSFERASE","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",5,"ILE A 357;GLY A 356;ASP A 316;LEU A 385;ALA A 328","None","1.14A","3kw2A-3pgyA:undetectable","3kw2A-3pgyA:20.67"],["3KW2_B_ADNB300_1","PROBABLE R-RNA METHYLTRANSFERASE","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",5,"ILE A 357;ASP A 316;LEU A 385;LEU A 323;ALA A 328","None","1.08A","3kw2B-3pgyA:undetectable","3kw2B-3pgyA:20.67"],["3KW2_B_ADNB300_1","PROBABLE R-RNA METHYLTRANSFERASE","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",5,"ILE A 357;GLY A 356;ASP A 316;LEU A 385;ALA A 328","None","1.17A","3kw2B-3pgyA:undetectable","3kw2B-3pgyA:20.67"],["3PGY_A_GLYA510_0","SERINE HYDROXYMETHYLTRANSFERASE","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",5,"GLU A  27;ILE A  29;GLU A  32;PHE A  34;ALA A 363","GLY A 510 (-2.8A);None;None;GLY A 510 (-4.0A);GLY A 510 (-2.9A)","0.42A","3pgyA-3pgyA:71.3;3pgyB-3pgyA:66.2","3pgyA-3pgyA:100.00;3pgyB-3pgyA:100.00"],["3PGY_B_GLYB509_0","SERINE HYDROXYMETHYLTRANSFERASE","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",4,"PHE A  34;THR A 366;LEU A 410;TYR A 411","GLY A 510 (-4.0A);None;None;None","0.18A","3pgyB-3pgyA:66.2","3pgyB-3pgyA:100.00"],["3PGY_B_GLYB511_0","SERINE HYDROXYMETHYLTRANSFERASE","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",4,"SER A 334;GLU A 391;LEU A 394;LYS A 398","None","0.59A","3pgyB-3pgyA:66.2","3pgyB-3pgyA:100.00"],["3PGY_B_GLYB511_0","SERINE HYDROXYMETHYLTRANSFERASE","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",4,"SER A 334;LEU A 394;GLN A 395;LYS A 398","None","0.89A","3pgyB-3pgyA:66.2","3pgyB-3pgyA:100.00"],["3VNS_A_DVAA602_0","NRPS ADENYLATION PROTEIN CYTC1","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",4,"PHE A 180;PHE A 183;GLY A 170;THR A 177","None","1.07A","3vnsA-3pgyA:undetectable","3vnsA-3pgyA:23.65"],["4FIA_A_0U9A601_1","CHOLESTEROL 24-HYDROXYLASE","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",5,"PHE A  82;ALA A 202;THR A 227;GLU A 272;ALA A 273","None","1.18A","4fiaA-3pgyA:undetectable","4fiaA-3pgyA:23.75"],["4FIA_A_198A602_1","CHOLESTEROL 24-HYDROXYLASE","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",5,"PHE A  82;ALA A 202;THR A 227;GLU A 272;ALA A 273","None","1.18A","4fiaA-3pgyA:undetectable","4fiaA-3pgyA:23.75"],["4J14_A_X2NA602_1","CHOLESTEROL 24-HYDROXYLASE","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",5,"ALA A 295;LEU A 296;PHE A 301;VAL A 315;ILE A 321","None","1.05A","4j14A-3pgyA:undetectable","4j14A-3pgyA:23.75"],["4KTT_C_SAMC404_0","S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",4,"HIS A 210;PRO A 211;SER A 175;SER A 305","None","1.15A","4kttC-3pgyA:undetectable","4kttC-3pgyA:22.52"],["4PCL_B_SAMB301_0","O-METHYLTRANSFERASE FAMILY PROTEIN","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",5,"GLN A  90;LEU A 259;GLY A 234;ALA A 199;ASN A  98","None","1.28A","4pclB-3pgyA:3.7","4pclB-3pgyA:21.36"],["4QVP_B_BO2B201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",5,"HIS A 200;SER A  31;THR A 223;THR A 222;GLY A 230","None","1.46A","4qvpV-3pgyA:undetectable;4qvpb-3pgyA:undetectable","4qvpV-3pgyA:21.27;4qvpb-3pgyA:20.60"],["4QVP_N_BO2N201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",5,"HIS A 200;SER A  31;THR A 223;THR A 222;GLY A 230","None","1.45A","4qvpH-3pgyA:undetectable;4qvpN-3pgyA:undetectable","4qvpH-3pgyA:21.27;4qvpN-3pgyA:20.60"],["4QVQ_B_BO2B201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",5,"HIS A 200;SER A  31;THR A 223;THR A 222;GLY A 230","None","1.46A","4qvqV-3pgyA:undetectable;4qvqb-3pgyA:undetectable","4qvqV-3pgyA:21.27;4qvqb-3pgyA:20.60"],["4QVQ_N_BO2N201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",5,"HIS A 200;SER A  31;THR A 223;THR A 222;GLY A 230","None","1.46A","4qvqH-3pgyA:undetectable;4qvqN-3pgyA:undetectable","4qvqH-3pgyA:21.27;4qvqN-3pgyA:20.60"],["4QWU_B_BO2B201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",5,"HIS A 200;SER A  31;THR A 223;THR A 222;GLY A 230","None","1.44A","4qwuV-3pgyA:undetectable;4qwub-3pgyA:undetectable","4qwuV-3pgyA:21.27;4qwub-3pgyA:20.60"],["4QWU_N_BO2N201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",5,"HIS A 200;SER A  31;THR A 223;THR A 222;GLY A 230","None","1.44A","4qwuH-3pgyA:undetectable;4qwuN-3pgyA:undetectable","4qwuH-3pgyA:21.27;4qwuN-3pgyA:20.60"],["4R1Z_B_AERB601_1","CYP17A1 PROTEIN","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",4,"ALA A 273;SER A  31;ALA A 202;THR A 222","None","0.86A","4r1zB-3pgyA:2.1","4r1zB-3pgyA:24.49"],["4UBE_A_2FAA401_2","ADENOSINE KINASE","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",4,"ALA A 267;VAL A  89;GLY A 234;THR A 224","None","1.14A","4ubeA-3pgyA:3.8","4ubeA-3pgyA:23.44"],["5E4D_B_BEZB203_0","HYDROXYNITRILE LYASE","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",4,"VAL A 268;ALA A 264;ILE A  73;THR A  70","None","1.06A","5e4dB-3pgyA:undetectable","5e4dB-3pgyA:18.62"],["6FBN_B_SAMB401_1","S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",4,"HIS A 210;PRO A 211;SER A 175;SER A 305","None","1.14A","6fbnB-3pgyA:undetectable","6fbnB-3pgyA:22.31"],["6FCB_A_SAMA405_0","S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2","3pgy","SERINE HYDROXYMETHYLTRANSFERASE","Staphylococcus aureus",4,"HIS A 210;PRO A 211;SER A 175;SER A 305","None","1.18A","6fcbA-3pgyA:undetectable","6fcbA-3pgyA:22.84"]]