SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ph5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBS_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE II)		 3ph5 BETA-LACTOGLOBULIN
(Bos
taurus) 		5 / 12 PHE A 152
LEU A 156
ILE A 163
ALA A  41
ALA A  39
 None
 1.02A 1cbsA-3ph5A:
6.0		 1cbsA-3ph5A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBS_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE II)		 3ph5 BETA-LACTOGLOBULIN
(Bos
taurus) 		5 / 12 PHE A 152
LEU A 156
ILE A 163
ALA A  41
LEU A 119
 None
 0.95A 1cbsA-3ph5A:
6.0		 1cbsA-3ph5A:
23.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GX8_A_RTLA1163_0
(BETA-LACTOGLOBULIN)		 3ph5 BETA-LACTOGLOBULIN
(Bos
taurus) 		5 / 9 LEU A  55
GLU A  78
ILE A  87
VAL A 108
MET A 123
 None
 0.96A 1gx8A-3ph5A:
29.9		 1gx8A-3ph5A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GX8_A_RTLA1163_0
(BETA-LACTOGLOBULIN)		 3ph5 BETA-LACTOGLOBULIN
(Bos
taurus) 		5 / 9 LEU A  55
GLU A  78
LYS A  85
VAL A 108
MET A 123
 None
 1.06A 1gx8A-3ph5A:
29.9		 1gx8A-3ph5A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GX8_A_RTLA1163_0
(BETA-LACTOGLOBULIN)		 3ph5 BETA-LACTOGLOBULIN
(Bos
taurus) 		6 / 9 LEU A  55
LEU A  74
GLU A  78
ILE A  87
VAL A 108
GLN A 136
 None
 0.58A 1gx8A-3ph5A:
29.9		 1gx8A-3ph5A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GX8_A_RTLA1163_0
(BETA-LACTOGLOBULIN)		 3ph5 BETA-LACTOGLOBULIN
(Bos
taurus) 		6 / 9 LEU A  55
LEU A  74
GLU A  78
LYS A  85
VAL A 108
GLN A 136
 None
 0.73A 1gx8A-3ph5A:
29.9		 1gx8A-3ph5A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GX8_A_RTLA1163_0
(BETA-LACTOGLOBULIN)		 3ph5 BETA-LACTOGLOBULIN
(Bos
taurus) 		6 / 9 LEU A  74
GLU A  78
ILE A  87
VAL A 108
PHE A 121
GLN A 136
 None
 0.85A 1gx8A-3ph5A:
29.9		 1gx8A-3ph5A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GX8_A_RTLA1163_0
(BETA-LACTOGLOBULIN)		 3ph5 BETA-LACTOGLOBULIN
(Bos
taurus) 		6 / 9 LEU A  74
GLU A  78
LYS A  85
VAL A 108
PHE A 121
GLN A 136
 None
 0.93A 1gx8A-3ph5A:
29.9		 1gx8A-3ph5A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GX9_A_REAA1163_1
(BETA-LACTOGLOBULIN)		 3ph5 BETA-LACTOGLOBULIN
(Bos
taurus) 		8 / 11 LEU A  55
VAL A  57
ILE A  72
LYS A  76
GLU A  78
LYS A  85
ILE A  87
GLN A 136
 None
 0.68A 1gx9A-3ph5A:
29.7		 1gx9A-3ph5A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GX9_A_REAA1163_1
(BETA-LACTOGLOBULIN)		 3ph5 BETA-LACTOGLOBULIN
(Bos
taurus) 		8 / 11 LEU A  55
VAL A  57
ILE A  72
LYS A  76
GLU A  78
LYS A  85
VAL A 108
GLN A 136
 None
 0.60A 1gx9A-3ph5A:
29.7		 1gx9A-3ph5A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GX9_A_REAA1163_1
(BETA-LACTOGLOBULIN)		 3ph5 BETA-LACTOGLOBULIN
(Bos
taurus) 		5 / 11 LEU A  55
VAL A  57
ILE A  87
LYS A  76
VAL A 108
 None
 1.38A 1gx9A-3ph5A:
29.7		 1gx9A-3ph5A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GX9_A_REAA1163_1
(BETA-LACTOGLOBULIN)		 3ph5 BETA-LACTOGLOBULIN
(Bos
taurus) 		7 / 11 LEU A  55
VAL A  57
LYS A  76
GLU A  78
LYS A  85
VAL A 108
MET A 123
 None
 0.97A 1gx9A-3ph5A:
29.7		 1gx9A-3ph5A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GX9_A_REAA1163_1
(BETA-LACTOGLOBULIN)		 3ph5 BETA-LACTOGLOBULIN
(Bos
taurus) 		8 / 11 VAL A  57
ILE A  72
LYS A  76
GLU A  78
LYS A  85
ILE A  87
PHE A 121
GLN A 136
 None
 0.80A 1gx9A-3ph5A:
29.7		 1gx9A-3ph5A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GX9_A_REAA1163_1
(BETA-LACTOGLOBULIN)		 3ph5 BETA-LACTOGLOBULIN
(Bos
taurus) 		8 / 11 VAL A  57
ILE A  72
LYS A  76
GLU A  78
LYS A  85
VAL A 108
PHE A 121
GLN A 136
 None
 0.75A 1gx9A-3ph5A:
29.7		 1gx9A-3ph5A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FR3_A_REAA300_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
2)		 3ph5 BETA-LACTOGLOBULIN
(Bos
taurus) 		5 / 12 PHE A 152
LEU A 156
ILE A 163
ALA A  41
ALA A  39
 None
 1.04A 2fr3A-3ph5A:
5.9		 2fr3A-3ph5A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G78_A_REAA200_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 3ph5 BETA-LACTOGLOBULIN
(Bos
taurus) 		5 / 12 PHE A 152
LEU A 156
ILE A 163
ALA A  41
LEU A 119
 None
 1.00A 2g78A-3ph5A:
undetectable		 2g78A-3ph5A:
23.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GJ5_A_VD3A163_1
(BETA-LACTOGLOBULIN)		 3ph5 BETA-LACTOGLOBULIN
(Bos
taurus) 		9 / 12 LEU A  55
VAL A  57
VAL A  59
ILE A  72
LEU A  74
LYS A  76
GLU A  78
ILE A  87
ILE A 100
 None
 0.65A 2gj5A-3ph5A:
29.2		 2gj5A-3ph5A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GJ5_A_VD3A163_1
(BETA-LACTOGLOBULIN)		 3ph5 BETA-LACTOGLOBULIN
(Bos
taurus) 		9 / 12 LEU A  55
VAL A  57
VAL A  59
ILE A  72
LEU A  74
LYS A  76
GLU A  78
ILE A 100
PHE A 121
 None
 0.59A 2gj5A-3ph5A:
29.2		 2gj5A-3ph5A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GJ5_A_VD3A164_1
(BETA-LACTOGLOBULIN)		 3ph5 BETA-LACTOGLOBULIN
(Bos
taurus) 		4 / 5 ASP A 153
LEU A 156
LYS A 157
MET A 161
 None
 0.86A 2gj5A-3ph5A:
29.2		 2gj5A-3ph5A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GJ5_A_VD3A164_1
(BETA-LACTOGLOBULIN)		 3ph5 BETA-LACTOGLOBULIN
(Bos
taurus) 		4 / 5 ASP A 153
LEU A 156
MET A 161
ARG A 164
 None
 0.92A 2gj5A-3ph5A:
29.2		 2gj5A-3ph5A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OMW_D_TE4D202_1
(BETA-LACTOGLOBULIN)		 3ph5 BETA-LACTOGLOBULIN
(Bos
taurus) 		7 / 9 LEU A  47
PRO A  54
ASN A 104
GLU A 105
ASN A 125
ALA A 127
SER A 132
 None
 0.30A 4omwD-3ph5A:
33.0		 4omwD-3ph5A:
96.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OMW_D_TE4D202_1
(BETA-LACTOGLOBULIN)		 3ph5 BETA-LACTOGLOBULIN
(Bos
taurus) 		6 / 9 LEU A  55
PRO A  54
ASN A 104
ASN A 125
ALA A 127
SER A 132
 None
 1.38A 4omwD-3ph5A:
33.0		 4omwD-3ph5A:
96.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7I_A_STIA1001_2
(MACROPHAGE
COLONY-STIMULATING
FACTOR 1 RECEPTOR)		 3ph5 BETA-LACTOGLOBULIN
(Bos
taurus) 		4 / 5 LEU A 120
VAL A  31
VAL A  59
TYR A 118
 None
 1.00A 4r7iA-3ph5A:
undetectable		 4r7iA-3ph5A:
18.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y0P_A_TE4A201_1
(BETA-LACTOGLOBULIN)		 3ph5 BETA-LACTOGLOBULIN
(Bos
taurus) 		11 / 12 LEU A  55
VAL A  57
LEU A  70
ILE A  72
LYS A  76
ILE A  87
ILE A 100
VAL A 108
VAL A 110
LEU A 119
PHE A 121
 None
 0.61A 4y0pA-3ph5A:
29.0		 4y0pA-3ph5A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y0P_A_TE4A201_1
(BETA-LACTOGLOBULIN)		 3ph5 BETA-LACTOGLOBULIN
(Bos
taurus) 		9 / 12 LEU A  55
VAL A  57
LEU A  70
LYS A  76
VAL A 108
VAL A 110
LEU A 119
PHE A 121
MET A 123
 None
 0.61A 4y0pA-3ph5A:
29.0		 4y0pA-3ph5A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y0Q_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 3ph5 BETA-LACTOGLOBULIN
(Bos
taurus) 		6 / 12 LEU A  55
VAL A  57
ILE A  87
LEU A  74
VAL A 108
PHE A 121
 None
 1.44A 4y0qA-3ph5A:
28.7		 4y0qA-3ph5A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y0Q_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 3ph5 BETA-LACTOGLOBULIN
(Bos
taurus) 		12 / 12 LEU A  55
VAL A  57
LEU A  70
ILE A  72
LEU A  74
LYS A  76
GLU A  78
VAL A 108
VAL A 110
LEU A 119
PHE A 121
MET A 123
 None
 0.73A 4y0qA-3ph5A:
28.7		 4y0qA-3ph5A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y0R_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 3ph5 BETA-LACTOGLOBULIN
(Bos
taurus) 		7 / 12 VAL A  57
LEU A  62
GLU A  78
LYS A  85
VAL A 108
PHE A 121
MET A 123
 None
 0.84A 4y0rA-3ph5A:
28.7		 4y0rA-3ph5A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y0R_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 3ph5 BETA-LACTOGLOBULIN
(Bos
taurus) 		7 / 12 VAL A  57
LEU A  62
LEU A  70
GLU A  78
LYS A  85
VAL A 108
PHE A 121
 None
 0.72A 4y0rA-3ph5A:
28.7		 4y0rA-3ph5A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y0R_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 3ph5 BETA-LACTOGLOBULIN
(Bos
taurus) 		8 / 12 VAL A  57
LEU A  62
LEU A  70
ILE A  72
LEU A  74
GLU A  78
ILE A  87
ILE A 100
 None
 0.64A 4y0rA-3ph5A:
28.7		 4y0rA-3ph5A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y0R_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 3ph5 BETA-LACTOGLOBULIN
(Bos
taurus) 		9 / 12 VAL A  57
LEU A  62
LEU A  70
ILE A  72
LEU A  74
GLU A  78
ILE A 100
VAL A 108
PHE A 121
 None
 0.66A 4y0rA-3ph5A:
28.7		 4y0rA-3ph5A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y0S_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 3ph5 BETA-LACTOGLOBULIN
(Bos
taurus) 		6 / 12 LEU A  62
LEU A  70
ILE A  72
ILE A 100
VAL A 108
LEU A 138
 None
 1.38A 4y0sA-3ph5A:
28.8		 4y0sA-3ph5A:
96.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y0S_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 3ph5 BETA-LACTOGLOBULIN
(Bos
taurus) 		11 / 12 VAL A  57
LEU A  62
LEU A  70
ILE A  72
LYS A  76
GLU A  78
ILE A 100
VAL A 108
VAL A 110
LEU A 119
PHE A 121
 None
 0.72A 4y0sA-3ph5A:
28.8		 4y0sA-3ph5A:
96.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Y0S_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 3ph5 BETA-LACTOGLOBULIN
(Bos
taurus) 		11 / 12 VAL A  57
LEU A  62
LEU A  70
ILE A  72
LYS A  76
GLU A  78
VAL A 108
VAL A 110
LEU A 119
PHE A 121
MET A 123
 None
 0.67A 4y0sA-3ph5A:
28.8		 4y0sA-3ph5A:
96.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NUK_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 3ph5 BETA-LACTOGLOBULIN
(Bos
taurus) 		6 / 10 VAL A  57
LYS A  85
ILE A 100
VAL A 108
ALA A 134
GLN A 136
 None
 0.66A 5nukA-3ph5A:
29.1		 5nukA-3ph5A:
95.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NUN_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 3ph5 BETA-LACTOGLOBULIN
(Bos
taurus) 		6 / 9 VAL A  57
ILE A  72
LEU A  74
ILE A  87
ILE A 100
ALA A 134
 None
 0.59A 5nunA-3ph5A:
29.1		 5nunA-3ph5A:
96.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NUN_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 3ph5 BETA-LACTOGLOBULIN
(Bos
taurus) 		5 / 9 VAL A  57
ILE A  87
LEU A  74
ASN A 104
ALA A 134
 None
 1.01A 5nunA-3ph5A:
29.1		 5nunA-3ph5A:
96.25