SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ph9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)
3ph9 ANTERIOR GRADIENT
PROTEIN 3 HOMOLOG

(Homo
sapiens)
3 / 3 SER A  74
GLU A 103
ASP A 106
None
0.55A 2zulA-3ph9A:
undetectable
2zulA-3ph9A:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)
3ph9 ANTERIOR GRADIENT
PROTEIN 3 HOMOLOG

(Homo
sapiens)
3 / 3 SER A  74
GLU A 103
ASP A 106
None
0.56A 3dmhA-3ph9A:
undetectable
3dmhA-3ph9A:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_2
(BETA-LACTAMASE)
3ph9 ANTERIOR GRADIENT
PROTEIN 3 HOMOLOG

(Homo
sapiens)
4 / 5 TYR A  54
PRO A 124
THR A 127
THR A  47
None
1.31A 3q07A-3ph9A:
undetectable
3q07A-3ph9A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_2
(BETA-LACTAMASE)
3ph9 ANTERIOR GRADIENT
PROTEIN 3 HOMOLOG

(Homo
sapiens)
4 / 5 TYR A  54
PRO A 124
THR A 127
THR A  47
None
1.27A 3q07B-3ph9A:
undetectable
3q07B-3ph9A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_1
(PUTATIVE REGULATORY
PROTEIN)
3ph9 ANTERIOR GRADIENT
PROTEIN 3 HOMOLOG

(Homo
sapiens)
3 / 3 TYR A 136
MET A 155
LEU A 148
None
0.93A 3vw1D-3ph9A:
undetectable
3vw1D-3ph9A:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)
3ph9 ANTERIOR GRADIENT
PROTEIN 3 HOMOLOG

(Homo
sapiens)
3 / 3 HIS A  67
GLU A  69
TRP A  38
None
1.22A 5odiD-3ph9A:
undetectable
5odiD-3ph9A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D9K_F_ACTF802_0
(UNCHARACTERIZED
PROTEIN)
3ph9 ANTERIOR GRADIENT
PROTEIN 3 HOMOLOG

(Homo
sapiens)
3 / 3 TYR A  48
ALA A  55
LEU A 126
None
0.69A 6d9kF-3ph9A:
undetectable
6d9kF-3ph9A:
11.25