SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3phg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		 3phg SHIKIMATE
DEHYDROGENASE
(Helicobacter
pylori) 		4 / 6 HIS A  15
ALA A 209
GLY A 230
TYR A 210
 None
 1.02A 1c8lA-3phgA:
2.7		 1c8lA-3phgA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		 3phg SHIKIMATE
DEHYDROGENASE
(Helicobacter
pylori) 		4 / 6 HIS A  15
ALA A 209
GLY A 230
TYR A 210
 None
 1.01A 1gfzA-3phgA:
4.7		 1gfzA-3phgA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3phg SHIKIMATE
DEHYDROGENASE
(Helicobacter
pylori) 		4 / 6 HIS A  15
ALA A 209
GLY A 230
TYR A 210
 None
 1.04A 1l5qA-3phgA:
2.2		 1l5qA-3phgA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3phg SHIKIMATE
DEHYDROGENASE
(Helicobacter
pylori) 		4 / 6 HIS A  15
ALA A 209
GLY A 230
TYR A 210
 None
 1.05A 1l5qB-3phgA:
1.8		 1l5qB-3phgA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3phg SHIKIMATE
DEHYDROGENASE
(Helicobacter
pylori) 		4 / 6 HIS A  15
ALA A 209
GLY A 230
TYR A 210
 None
 1.10A 1l7xA-3phgA:
undetectable		 1l7xA-3phgA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3phg SHIKIMATE
DEHYDROGENASE
(Helicobacter
pylori) 		4 / 6 HIS A  15
ALA A 209
GLY A 230
TYR A 210
 None
 1.07A 1l7xB-3phgA:
undetectable		 1l7xB-3phgA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_1
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))		 3phg SHIKIMATE
DEHYDROGENASE
(Helicobacter
pylori) 		4 / 4 SER A 248
SER A 246
LEU A 240
PHE A 242
 None
 1.35A 1r5lA-3phgA:
0.0		 1r5lA-3phgA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3phg SHIKIMATE
DEHYDROGENASE
(Helicobacter
pylori) 		3 / 3 SER A 112
ASP A 105
CYH A  86
 None
 1.13A 2br4E-3phgA:
4.8		 2br4E-3phgA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_A_ERYA1400_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 3phg SHIKIMATE
DEHYDROGENASE
(Helicobacter
pylori) 		5 / 11 HIS A  22
VAL A  93
ALA A 247
SER A 248
ASP A 105
 None
 1.21A 2iyfA-3phgA:
5.7		 2iyfA-3phgA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		 3phg SHIKIMATE
DEHYDROGENASE
(Helicobacter
pylori) 		4 / 6 ALA A 134
LEU A 133
ALA A 179
THR A 180
 None
 0.72A 3b6hA-3phgA:
undetectable		 3b6hA-3phgA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		 3phg SHIKIMATE
DEHYDROGENASE
(Helicobacter
pylori) 		4 / 6 ALA A 134
LEU A 133
ALA A 179
THR A 180
 None
 0.72A 3b6hB-3phgA:
undetectable		 3b6hB-3phgA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3phg SHIKIMATE
DEHYDROGENASE
(Helicobacter
pylori) 		4 / 6 HIS A  15
ALA A 209
GLY A 230
TYR A 210
 None
 1.05A 3dd1A-3phgA:
undetectable		 3dd1A-3phgA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3phg SHIKIMATE
DEHYDROGENASE
(Helicobacter
pylori) 		4 / 6 HIS A  15
ALA A 209
GLY A 230
TYR A 210
 None
 1.04A 3dd1B-3phgA:
undetectable		 3dd1B-3phgA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3phg SHIKIMATE
DEHYDROGENASE
(Helicobacter
pylori) 		4 / 6 HIS A  15
ALA A 209
GLY A 230
TYR A 210
 None
 1.02A 3ddsA-3phgA:
2.7		 3ddsA-3phgA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3phg SHIKIMATE
DEHYDROGENASE
(Helicobacter
pylori) 		4 / 6 HIS A  15
ALA A 209
GLY A 230
TYR A 210
 None
 1.03A 3ddsB-3phgA:
undetectable		 3ddsB-3phgA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3phg SHIKIMATE
DEHYDROGENASE
(Helicobacter
pylori) 		4 / 6 HIS A  15
ALA A 209
GLY A 230
TYR A 210
 None
 1.03A 3ddwA-3phgA:
3.0		 3ddwA-3phgA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3phg SHIKIMATE
DEHYDROGENASE
(Helicobacter
pylori) 		4 / 6 HIS A  15
ALA A 209
GLY A 230
TYR A 210
 None
 1.03A 3ddwB-3phgA:
2.4		 3ddwB-3phgA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA310_1
(BETA-LACTAMASE)		 3phg SHIKIMATE
DEHYDROGENASE
(Helicobacter
pylori) 		4 / 8 LEU A 184
ALA A 179
GLY A  10
PRO A  12
 None
 0.91A 3ny4A-3phgA:
undetectable		 3ny4A-3phgA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_C_ACTC1113_0
(BLR5658 PROTEIN)		 3phg SHIKIMATE
DEHYDROGENASE
(Helicobacter
pylori) 		4 / 4 ASN A 148
ALA A 126
GLY A 125
THR A 180
 None
 1.33A 4bboC-3phgA:
undetectable		 4bboC-3phgA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 3phg SHIKIMATE
DEHYDROGENASE
(Helicobacter
pylori) 		5 / 12 ILE A  50
LEU A  92
SER A  18
GLY A  10
HIS A  15
 None
 1.10A 5l6eA-3phgA:
2.1		 5l6eA-3phgA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3phg SHIKIMATE
DEHYDROGENASE
(Helicobacter
pylori) 		4 / 7 LEU A 190
PRO A 168
LEU A 195
TYR A 198
 None
 1.06A 5t7bA-3phgA:
3.7		 5t7bA-3phgA:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6N_A_SALA505_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 3phg SHIKIMATE
DEHYDROGENASE
(Helicobacter
pylori) 		4 / 8 SER A  18
HIS A  22
PHE A 245
THR A 104
 None
 1.38A 5u6nA-3phgA:
4.7		 5u6nA-3phgA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6N_B_SALB504_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 3phg SHIKIMATE
DEHYDROGENASE
(Helicobacter
pylori) 		4 / 6 SER A  18
HIS A  22
PHE A 245
THR A 104
 None
 1.38A 5u6nB-3phgA:
4.6		 5u6nB-3phgA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_A_ACRA602_1
(-)		 3phg SHIKIMATE
DEHYDROGENASE
(Helicobacter
pylori) 		5 / 12 GLY A 128
GLY A 127
VAL A 146
ASN A 148
GLY A 153
 None
 0.95A 6gneA-3phgA:
undetectable		 6gneA-3phgA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_1
(-)		 3phg SHIKIMATE
DEHYDROGENASE
(Helicobacter
pylori) 		5 / 12 GLY A 128
GLY A 127
VAL A 146
ASN A 148
GLY A 153
 None
 0.94A 6gneB-3phgA:
5.5		 6gneB-3phgA:
19.31