SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pi7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 3pi7 NADH OXIDOREDUCTASE
(Mesorhizobium
loti) 		4 / 8 VAL A 103
GLY A 104
THR A  89
ILE A   6
 None
 0.66A 2a1mB-3pi7A:
undetectable		 2a1mB-3pi7A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_B_SAMB202_0
(UPF0066 PROTEIN
AF_0241)		 3pi7 NADH OXIDOREDUCTASE
(Mesorhizobium
loti) 		5 / 12 GLN A  38
ALA A 329
LYS A  11
GLY A 117
LEU A 326
 None
None
None
GOL  A 349 (-3.3A)
None
 1.21A 2nv4B-3pi7A:
undetectable		 2nv4B-3pi7A:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_L_ASDL1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3pi7 NADH OXIDOREDUCTASE
(Mesorhizobium
loti) 		4 / 7 PHE A 109
PRO A 348
ALA A  58
ALA A 123
 None
 0.95A 2vcvL-3pi7A:
undetectable		 2vcvL-3pi7A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_B_VD3B700_1
(CYTOCHROME P450 2R1)		 3pi7 NADH OXIDOREDUCTASE
(Mesorhizobium
loti) 		5 / 12 LEU A  15
ALA A 120
ALA A 329
VAL A 333
THR A 111
 None
None
None
None
GOL  A 349 (-3.8A)
 0.99A 3c6gB-3pi7A:
undetectable		 3c6gB-3pi7A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_B_D2VB602_1
(CYTOCHROME P450 2R1)		 3pi7 NADH OXIDOREDUCTASE
(Mesorhizobium
loti) 		5 / 12 LEU A  15
ALA A 120
ALA A 329
VAL A 333
THR A 111
 None
None
None
None
GOL  A 349 (-3.8A)
 1.00A 3czhB-3pi7A:
undetectable		 3czhB-3pi7A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_B_SAMB302_0
(UNCHARACTERIZED
PROTEIN Q5LES9)		 3pi7 NADH OXIDOREDUCTASE
(Mesorhizobium
loti) 		5 / 12 GLY A  86
GLY A 117
GLY A  83
LEU A  13
ALA A 123
 None
GOL  A 349 (-3.3A)
GOL  A 349 (-4.0A)
None
None
 0.89A 3kkzB-3pi7A:
3.6		 3kkzB-3pi7A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_B_VORB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3pi7 NADH OXIDOREDUCTASE
(Mesorhizobium
loti) 		5 / 11 ILE A 146
ALA A  58
ALA A 123
ALA A 110
THR A 111
 None
None
None
None
GOL  A 349 (-3.8A)
 1.13A 3mdtB-3pi7A:
undetectable		 3mdtB-3pi7A:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_B_CGEB501_1
(CYTOCHROME P450 2B4)		 3pi7 NADH OXIDOREDUCTASE
(Mesorhizobium
loti) 		4 / 8 ILE A 181
ALA A 202
VAL A 195
VAL A 193
 None
 0.90A 3me6B-3pi7A:
undetectable		 3me6B-3pi7A:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_C_BEZC264_0
(CARNITINYL-COA
DEHYDRATASE)		 3pi7 NADH OXIDOREDUCTASE
(Mesorhizobium
loti) 		4 / 6 ALA A  82
ILE A  68
LEU A  15
ALA A  12
 GOL  A 349 (-4.7A)
None
None
None
 0.66A 3r9sC-3pi7A:
undetectable		 3r9sC-3pi7A:
25.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TX2_A_BEZA251_0
(PROBABLE
6-PHOSPHOGLUCONOLACT
ONASE)		 3pi7 NADH OXIDOREDUCTASE
(Mesorhizobium
loti) 		4 / 7 ALA A 123
TRP A 116
MET A  10
ALA A 120
 None
 1.43A 3tx2A-3pi7A:
3.3		 3tx2A-3pi7A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_A_SAMA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3pi7 NADH OXIDOREDUCTASE
(Mesorhizobium
loti) 		5 / 12 VAL A 227
GLY A 172
ILE A 192
ILE A 248
LEU A 224
 None
 1.02A 4iv0A-3pi7A:
2.9		 4iv0A-3pi7A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JJK_A_FOLA601_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 3pi7 NADH OXIDOREDUCTASE
(Mesorhizobium
loti) 		4 / 8 ASN A 250
ALA A 247
PRO A 243
LEU A 224
 None
 0.91A 4jjkA-3pi7A:
undetectable		 4jjkA-3pi7A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_SAMB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3pi7 NADH OXIDOREDUCTASE
(Mesorhizobium
loti) 		5 / 12 VAL A 227
GLY A 172
ILE A 192
ILE A 248
LEU A 224
 None
 1.02A 4mwzB-3pi7A:
3.1		 4mwzB-3pi7A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTJ_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3pi7 NADH OXIDOREDUCTASE
(Mesorhizobium
loti) 		3 / 3 ASP A 198
LYS A 216
LEU A 244
 None
 1.06A 4ptjA-3pi7A:
undetectable		 4ptjA-3pi7A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIN_H_QI9H1226_0
(FAB 314.3)		 3pi7 NADH OXIDOREDUCTASE
(Mesorhizobium
loti) 		5 / 12 THR A 318
GLY A 314
ARG A 310
LEU A 179
PRO A 149
 None
 1.24A 4uinH-3pi7A:
undetectable
4uinL-3pi7A:
undetectable		 4uinH-3pi7A:
23.90
4uinL-3pi7A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NU7_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 4)		 3pi7 NADH OXIDOREDUCTASE
(Mesorhizobium
loti) 		4 / 8 LEU A 133
ALA A 110
VAL A 137
MET A 145
 None
 0.83A 5nu7A-3pi7A:
undetectable		 5nu7A-3pi7A:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PBE_A_TYLA2001_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 3pi7 NADH OXIDOREDUCTASE
(Mesorhizobium
loti) 		4 / 6 PRO A 191
VAL A 212
VAL A 195
ILE A 181
 None
 0.80A 5pbeA-3pi7A:
undetectable		 5pbeA-3pi7A:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		 3pi7 NADH OXIDOREDUCTASE
(Mesorhizobium
loti) 		5 / 9 SER A 118
ALA A 108
GLY A  88
ALA A 144
GLY A 142
 None
 1.14A 6bklE-3pi7A:
undetectable
6bklF-3pi7A:
undetectable
6bklG-3pi7A:
undetectable
6bklH-3pi7A:
undetectable		 6bklE-3pi7A:
8.24
6bklF-3pi7A:
8.24
6bklG-3pi7A:
8.24
6bklH-3pi7A:
8.24