SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pig'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3pig BETA-FRUCTOFURANOSID
ASE
(Bifidobacterium
longum) 		5 / 12 ILE A 343
GLY A 254
VAL A 252
ALA A 257
SER A 256
 None
 1.07A 1kiaA-3pigA:
undetectable		 1kiaA-3pigA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRL_A_DOLA300_1
(STREPTOGRAMIN A
ACETYLTRANSFERASE)		 3pig BETA-FRUCTOFURANOSID
ASE
(Bifidobacterium
longum) 		5 / 11 ILE A 426
LEU A 480
PRO A 447
LEU A 448
VAL A 469
 None
 1.38A 1mrlA-3pigA:
undetectable
1mrlB-3pigA:
undetectable		 1mrlA-3pigA:
17.11
1mrlB-3pigA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA734_1
(ALPHA AMYLASE)		 3pig BETA-FRUCTOFURANOSID
ASE
(Bifidobacterium
longum) 		4 / 6 ASN A  53
HIS A 132
GLY A  79
TRP A 134
 None
 1.26A 1mxdA-3pigA:
undetectable		 1mxdA-3pigA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3pig BETA-FRUCTOFURANOSID
ASE
(Bifidobacterium
longum) 		5 / 12 ILE A 343
GLY A 254
VAL A 252
ALA A 257
SER A 256
 None
 1.05A 1nbhA-3pigA:
undetectable		 1nbhA-3pigA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3pig BETA-FRUCTOFURANOSID
ASE
(Bifidobacterium
longum) 		5 / 12 ILE A 343
GLY A 254
VAL A 252
ALA A 257
SER A 256
 None
 1.05A 1nbhB-3pigA:
undetectable		 1nbhB-3pigA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3pig BETA-FRUCTOFURANOSID
ASE
(Bifidobacterium
longum) 		5 / 12 ILE A 343
GLY A 254
VAL A 252
ALA A 257
SER A 256
 None
 1.06A 1nbhC-3pigA:
undetectable		 1nbhC-3pigA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3pig BETA-FRUCTOFURANOSID
ASE
(Bifidobacterium
longum) 		5 / 12 ILE A 343
GLY A 254
VAL A 252
ALA A 257
SER A 256
 None
 1.05A 1nbhD-3pigA:
undetectable		 1nbhD-3pigA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3pig BETA-FRUCTOFURANOSID
ASE
(Bifidobacterium
longum) 		5 / 12 ILE A 343
GLY A 254
VAL A 252
ALA A 257
SER A 256
 None
 0.99A 1nbiA-3pigA:
undetectable		 1nbiA-3pigA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3pig BETA-FRUCTOFURANOSID
ASE
(Bifidobacterium
longum) 		5 / 12 ILE A 343
GLY A 254
VAL A 252
ALA A 257
SER A 256
 None
 1.01A 1nbiB-3pigA:
undetectable		 1nbiB-3pigA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_1
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 3pig BETA-FRUCTOFURANOSID
ASE
(Bifidobacterium
longum) 		3 / 3 HIS A  72
ASP A 110
ASN A 136
 None
 0.88A 1wg8B-3pigA:
undetectable		 1wg8B-3pigA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 3pig BETA-FRUCTOFURANOSID
ASE
(Bifidobacterium
longum) 		4 / 8 HIS A 477
VAL A 473
LEU A 448
THR A 449
 None
 0.81A 2gehA-3pigA:
undetectable		 2gehA-3pigA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 3pig BETA-FRUCTOFURANOSID
ASE
(Bifidobacterium
longum) 		5 / 12 LEU A 397
LEU A 453
VAL A 429
LEU A 460
THR A 394
 None
 1.44A 2q7kA-3pigA:
undetectable		 2q7kA-3pigA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_B_SAMB402_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 3pig BETA-FRUCTOFURANOSID
ASE
(Bifidobacterium
longum) 		5 / 12 PHE A 195
TYR A 129
PHE A 127
PHE A 113
GLY A 115
 None
 1.37A 2zznB-3pigA:
undetectable		 2zznB-3pigA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA608_1
(CHITINASE A)		 3pig BETA-FRUCTOFURANOSID
ASE
(Bifidobacterium
longum) 		4 / 6 ASN A 136
ALA A 135
HIS A 177
ASP A 144
 None
 1.24A 3aruA-3pigA:
undetectable		 3aruA-3pigA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA702_1
(CARBONIC ANHYDRASE 2)		 3pig BETA-FRUCTOFURANOSID
ASE
(Bifidobacterium
longum) 		4 / 7 VAL A 197
TYR A 179
LYS A 174
PRO A 171
 None
 1.10A 3hs4A-3pigA:
undetectable		 3hs4A-3pigA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_1
(WBDD)		 3pig BETA-FRUCTOFURANOSID
ASE
(Bifidobacterium
longum) 		5 / 6 TYR A  40
ARG A  96
ASP A 465
GLU A 364
LEU A 517
 None
 1.21A 4ax8A-3pigA:
undetectable		 4ax8A-3pigA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_1
(WBDD)		 3pig BETA-FRUCTOFURANOSID
ASE
(Bifidobacterium
longum) 		4 / 6 TYR A  40
ARG A  96
ASP A 465
GLU A 364
 None
 1.12A 4azvA-3pigA:
undetectable		 4azvA-3pigA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR2_A_PARA1609_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 3pig BETA-FRUCTOFURANOSID
ASE
(Bifidobacterium
longum) 		3 / 3 TYR A 485
ARG A 433
SER A 484
 None
 0.84A 4dr2I-3pigA:
undetectable
4dr2J-3pigA:
undetectable		 4dr2I-3pigA:
12.95
4dr2J-3pigA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF7_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 3pig BETA-FRUCTOFURANOSID
ASE
(Bifidobacterium
longum) 		3 / 3 TYR A 485
ARG A 433
SER A 484
 None
 0.96A 4lf7I-3pigA:
undetectable
4lf7J-3pigA:
undetectable		 4lf7I-3pigA:
12.95
4lf7J-3pigA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF8_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 3pig BETA-FRUCTOFURANOSID
ASE
(Bifidobacterium
longum) 		3 / 3 TYR A 485
ARG A 433
SER A 484
 None
 0.96A 4lf8I-3pigA:
undetectable
4lf8J-3pigA:
undetectable		 4lf8I-3pigA:
12.95
4lf8J-3pigA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUF_A_ACTA605_0
(SERUM ALBUMIN)		 3pig BETA-FRUCTOFURANOSID
ASE
(Bifidobacterium
longum) 		4 / 4 ALA A 151
HIS A  17
PHE A 101
LEU A 105
 None
 1.46A 4lufA-3pigA:
undetectable		 4lufA-3pigA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN)		 3pig BETA-FRUCTOFURANOSID
ASE
(Bifidobacterium
longum) 		5 / 12 ARG A 203
ALA A 257
MET A 258
GLY A 259
PHE A 232
 None
 1.15A 4r29C-3pigA:
undetectable		 4r29C-3pigA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RFQ_A_SAMA401_1
(HISTIDINE PROTEIN
METHYLTRANSFERASE 1
HOMOLOG)		 3pig BETA-FRUCTOFURANOSID
ASE
(Bifidobacterium
longum) 		4 / 4 THR A 418
GLY A 439
ASP A 440
SER A 484
 None
 1.22A 4rfqA-3pigA:
undetectable		 4rfqA-3pigA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A7M_A_ACTA1923_0
(BETA-XYLOSIDASE)		 3pig BETA-FRUCTOFURANOSID
ASE
(Bifidobacterium
longum) 		3 / 3 ASP A 432
ARG A 404
TYR A 443
 None
 1.03A 5a7mA-3pigA:
undetectable		 5a7mA-3pigA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A7M_B_ACTB1924_0
(BETA-XYLOSIDASE)		 3pig BETA-FRUCTOFURANOSID
ASE
(Bifidobacterium
longum) 		3 / 3 ASP A 432
ARG A 404
TYR A 443
 None
 1.05A 5a7mB-3pigA:
undetectable		 5a7mB-3pigA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		 3pig BETA-FRUCTOFURANOSID
ASE
(Bifidobacterium
longum) 		5 / 12 MET A 393
ILE A 395
VAL A 420
GLY A 424
LEU A 448
 None
 1.06A 5byjA-3pigA:
undetectable		 5byjA-3pigA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_B_ACTB1321_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT)		 3pig BETA-FRUCTOFURANOSID
ASE
(Bifidobacterium
longum) 		3 / 3 THR A 449
ASP A 450
ALA A 451
 None
 0.05A 5g5gB-3pigA:
undetectable		 5g5gB-3pigA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_B_AC2B301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3pig BETA-FRUCTOFURANOSID
ASE
(Bifidobacterium
longum) 		5 / 10 GLY A 346
ALA A 354
VAL A 352
GLU A 342
ASP A 347
 None
 1.20A 5i3cB-3pigA:
undetectable		 5i3cB-3pigA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I71_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 3pig BETA-FRUCTOFURANOSID
ASE
(Bifidobacterium
longum) 		5 / 12 ILE A 395
GLY A 424
GLY A 406
LEU A 407
GLY A 456
 None
 1.35A 5i71A-3pigA:
undetectable		 5i71A-3pigA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_2
(TUBULIN BETA-2B
CHAIN)		 3pig BETA-FRUCTOFURANOSID
ASE
(Bifidobacterium
longum) 		3 / 3 THR A   5
PRO A 182
ARG A 180
 None
 0.82A 5nd7B-3pigA:
undetectable		 5nd7B-3pigA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		 3pig BETA-FRUCTOFURANOSID
ASE
(Bifidobacterium
longum) 		5 / 12 MET A 393
ILE A 395
VAL A 420
LEU A 397
LEU A 448
 None
 1.25A 5tiwA-3pigA:
undetectable		 5tiwA-3pigA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3pig BETA-FRUCTOFURANOSID
ASE
(Bifidobacterium
longum) 		3 / 3 ASN A 272
VAL A 431
HIS A 299
 None
 0.80A 6a5yD-3pigA:
undetectable		 6a5yD-3pigA:
9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWP_A_FVXA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 3pig BETA-FRUCTOFURANOSID
ASE
(Bifidobacterium
longum) 		5 / 9 ASN A 155
SER A 160
PHE A 101
GLY A  57
THR A 150
 None
 1.11A 6awpA-3pigA:
undetectable		 6awpA-3pigA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FK2_A_SORA302_0
(GALECTIN-3)		 3pig BETA-FRUCTOFURANOSID
ASE
(Bifidobacterium
longum) 		4 / 4 ARG A 461
GLU A 392
GLU A 360
ARG A 363
 None
 1.06A 6fk2A-3pigA:
9.9		 6fk2A-3pigA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_C_AM2C301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3pig BETA-FRUCTOFURANOSID
ASE
(Bifidobacterium
longum) 		4 / 8 ASP A 465
HIS A  44
GLU A 518
GLU A 364
 None
 1.08A 6mn4C-3pigA:
undetectable		 6mn4C-3pigA:
19.73