SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pin'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_A_SHHA2452_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 3pin PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
(Saccharomyces
cerevisiae) 		5 / 11 LEU B 120
ILE B  19
HIS B 179
HIS B 100
GLY B  24
 None
 1.18A 1zz1A-3pinB:
undetectable		 1zz1A-3pinB:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1004_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3pin PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
(Saccharomyces
cerevisiae) 		4 / 7 VAL B  80
LEU B  37
PHE B  96
THR B  29
 None
 1.10A 2f78B-3pinB:
undetectable		 2f78B-3pinB:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBU_B_ADNB502_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 3pin PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
(Saccharomyces
cerevisiae) 		4 / 5 ASP B  73
PHE B  74
TYR B  48
VAL B  77
 None
 1.21A 2zbuB-3pinB:
0.0		 2zbuB-3pinB:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U52_A_CUA515_0
(PHENOL HYDROXYLASE
COMPONENT PHL
PHENOL HYDROXYLASE
COMPONENT PHN)		 3pin PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
(Saccharomyces
cerevisiae) 		3 / 3 HIS B 100
HIS B 179
ILE B  99
 None
 0.83A 3u52A-3pinB:
undetectable
3u52C-3pinB:
undetectable		 3u52A-3pinB:
16.67
3u52C-3pinB:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QSA615_1
(SERUM ALBUMIN)		 3pin PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
(Saccharomyces
cerevisiae) 		4 / 8 LEU B  78
HIS B 179
LEU B  92
ILE B  99
 None
 0.76A 5v0vA-3pinB:
undetectable		 5v0vA-3pinB:
17.11