SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pj0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHU_A_ESTA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 3pj0 LMO0305 PROTEIN
(Listeria
monocytogenes) 		5 / 12 GLY A 150
ASN A 289
LEU A 153
ILE A 149
LEU A 124
 None
 1.17A 1lhuA-3pj0A:
undetectable		 1lhuA-3pj0A:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_A_FUAA702_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3pj0 LMO0305 PROTEIN
(Listeria
monocytogenes) 		5 / 12 THR A 313
PHE A 273
LEU A 269
VAL A 335
ALA A 338
 None
 1.24A 1q23A-3pj0A:
2.0
1q23B-3pj0A:
undetectable		 1q23A-3pj0A:
21.88
1q23B-3pj0A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_D_FUAD705_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3pj0 LMO0305 PROTEIN
(Listeria
monocytogenes) 		5 / 12 THR A 313
PHE A 273
LEU A 269
VAL A 335
ALA A 338
 None
 1.21A 1q23D-3pj0A:
2.1
1q23E-3pj0A:
2.2		 1q23D-3pj0A:
21.88
1q23E-3pj0A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_H_FUAH709_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3pj0 LMO0305 PROTEIN
(Listeria
monocytogenes) 		5 / 12 THR A 313
PHE A 273
LEU A 269
VAL A 335
ALA A 338
 None
 1.23A 1q23H-3pj0A:
1.9
1q23I-3pj0A:
1.6		 1q23H-3pj0A:
21.88
1q23I-3pj0A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 3pj0 LMO0305 PROTEIN
(Listeria
monocytogenes) 		6 / 11 PHE A 331
VAL A 333
ILE A 317
GLY A 316
LEU A 269
PHE A 351
 None
 1.30A 1z11B-3pj0A:
undetectable		 1z11B-3pj0A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 3pj0 LMO0305 PROTEIN
(Listeria
monocytogenes) 		5 / 10 VAL A 333
ILE A 317
GLY A 316
LEU A 269
PHE A 351
 None
 1.12A 1z11C-3pj0A:
undetectable		 1z11C-3pj0A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 3pj0 LMO0305 PROTEIN
(Listeria
monocytogenes) 		6 / 10 PHE A 331
VAL A 333
ILE A 317
GLY A 316
LEU A 269
PHE A 351
 None
 1.34A 1z11D-3pj0A:
undetectable		 1z11D-3pj0A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_A_ADNA2001_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3pj0 LMO0305 PROTEIN
(Listeria
monocytogenes) 		4 / 7 ARG A 255
GLU A 253
ALA A  30
ASN A  33
 None
 0.99A 2ejfA-3pj0A:
2.5		 2ejfA-3pj0A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_D_VD3D2001_1
(VITAMIN D
HYDROXYLASE)		 3pj0 LMO0305 PROTEIN
(Listeria
monocytogenes) 		5 / 12 ILE A 183
LEU A 153
LEU A 197
ALA A 191
LEU A 175
 None
 1.09A 3a50D-3pj0A:
undetectable		 3a50D-3pj0A:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_C_VDYC6178_1
(VITAMIN D
HYDROXYLASE)		 3pj0 LMO0305 PROTEIN
(Listeria
monocytogenes) 		5 / 12 ILE A 305
LEU A 358
ASN A 274
ILE A 317
LEU A 321
 None
 1.20A 3a51C-3pj0A:
undetectable		 3a51C-3pj0A:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAV_A_RAVA183_1
(FERRITIN LIGHT CHAIN)		 3pj0 LMO0305 PROTEIN
(Listeria
monocytogenes) 		4 / 6 LEU A  27
SER A 247
ALA A 248
LEU A  31
 None
 1.06A 3ravA-3pj0A:
undetectable		 3ravA-3pj0A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RD0_A_EDPA175_1
(FERRITIN LIGHT CHAIN)		 3pj0 LMO0305 PROTEIN
(Listeria
monocytogenes) 		4 / 6 LEU A  27
SER A 247
ALA A 248
LEU A  31
 None
 1.06A 3rd0A-3pj0A:
undetectable		 3rd0A-3pj0A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_A_9PLA501_1
(CYTOCHROME P450 2A6)		 3pj0 LMO0305 PROTEIN
(Listeria
monocytogenes) 		5 / 11 VAL A 333
ILE A 317
GLY A 316
LEU A 269
PHE A 351
 None
 1.07A 3t3rA-3pj0A:
undetectable		 3t3rA-3pj0A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_A_ADNA353_1
(ADENOSINE KINASE)		 3pj0 LMO0305 PROTEIN
(Listeria
monocytogenes) 		5 / 12 ILE A 209
GLY A 210
ASN A  19
GLY A 336
ASP A 337
 None
LLP  A 207 ( 3.6A)
None
None
None
 0.92A 3uboA-3pj0A:
3.6		 3uboA-3pj0A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_A_ML1A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3pj0 LMO0305 PROTEIN
(Listeria
monocytogenes) 		4 / 8 PHE A 205
TYR A 206
GLY A 177
ILE A 183
 None
LLP  A 207 ( 3.6A)
None
None
 0.93A 4qoiA-3pj0A:
undetectable
4qoiB-3pj0A:
undetectable		 4qoiA-3pj0A:
19.56
4qoiB-3pj0A:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_F_MN9F401_0
(N-ACETYLNEURAMINATE
LYASE)		 3pj0 LMO0305 PROTEIN
(Listeria
monocytogenes) 		4 / 5 LEU A  38
ASP A  35
TYR A 242
LEU A 246
 None
 1.21A 4wozF-3pj0A:
undetectable
4wozH-3pj0A:
undetectable		 4wozF-3pj0A:
22.74
4wozH-3pj0A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_D_ADND303_1
(5'/3'-NUCLEOTIDASE
SURE)		 3pj0 LMO0305 PROTEIN
(Listeria
monocytogenes) 		5 / 10 LEU A  16
GLY A  17
ASN A 289
SER A 334
ILE A 342
 None
 1.15A 4xj7C-3pj0A:
undetectable
4xj7D-3pj0A:
undetectable		 4xj7C-3pj0A:
21.89
4xj7D-3pj0A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZF8_A_MYTA502_1
(BIFUNCTIONAL
P-450/NADPH-P450
REDUCTASE)		 3pj0 LMO0305 PROTEIN
(Listeria
monocytogenes) 		4 / 6 VAL A 335
LEU A 347
ALA A 265
ALA A 270
 None
 0.77A 4zf8A-3pj0A:
undetectable		 4zf8A-3pj0A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UVM_B_ADNB207_1
(HISTIDINE TRIAD
(HIT) PROTEIN)		 3pj0 LMO0305 PROTEIN
(Listeria
monocytogenes) 		5 / 12 VAL A 279
PHE A 295
ILE A 305
LEU A 306
VAL A 293
 None
 0.88A 5uvmB-3pj0A:
undetectable		 5uvmB-3pj0A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WM2_A_SALA601_1
(SALICYLATE-AMP
LIGASE)		 3pj0 LMO0305 PROTEIN
(Listeria
monocytogenes) 		5 / 9 HIS A 174
PHE A 198
CYH A 195
GLY A 177
LEU A 180
 None
 1.46A 5wm2A-3pj0A:
3.2		 5wm2A-3pj0A:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3pj0 LMO0305 PROTEIN
(Listeria
monocytogenes) 		5 / 12 LEU A 153
GLY A 177
GLN A  75
ILE A 194
LEU A  79
 None
None
LLP  A 207 ( 4.7A)
None
None
 1.23A 5y2tA-3pj0A:
undetectable		 5y2tA-3pj0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3pj0 LMO0305 PROTEIN
(Listeria
monocytogenes) 		5 / 10 PRO A 145
SER A 288
LEU A 124
ILE A 149
GLY A 150
 None
 1.17A 6dlzA-3pj0A:
2.5
6dlzD-3pj0A:
4.8		 6dlzA-3pj0A:
13.35
6dlzD-3pj0A:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3pj0 LMO0305 PROTEIN
(Listeria
monocytogenes) 		5 / 10 ILE A 149
GLY A 150
PRO A 145
SER A 288
LEU A 124
 None
 1.17A 6dlzB-3pj0A:
3.3
6dlzC-3pj0A:
2.5		 6dlzB-3pj0A:
13.35
6dlzC-3pj0A:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3pj0 LMO0305 PROTEIN
(Listeria
monocytogenes) 		5 / 10 PRO A 145
SER A 288
LEU A 124
ILE A 149
GLY A 150
 None
 1.17A 6dm1A-3pj0A:
2.4
6dm1D-3pj0A:
4.0		 6dm1A-3pj0A:
13.35
6dm1D-3pj0A:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3pj0 LMO0305 PROTEIN
(Listeria
monocytogenes) 		5 / 10 ILE A 149
GLY A 150
PRO A 145
SER A 288
LEU A 124
 None
 1.17A 6dm1B-3pj0A:
3.3
6dm1C-3pj0A:
2.3		 6dm1B-3pj0A:
13.35
6dm1C-3pj0A:
13.35