SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pj9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_CCSB381_0
(ESTROGEN RECEPTOR)		 3pj9 NUCLEOSIDE
DIPHOSPHATE KINASE
(Campylobacter
jejuni) 		3 / 3 GLU A 121
ALA A 123
SER A 117
 None
 0.66A 1errB-3pj9A:
undetectable		 1errB-3pj9A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1F86_B_T44B528_1
(TRANSTHYRETIN
THR119MET VARIANT)		 3pj9 NUCLEOSIDE
DIPHOSPHATE KINASE
(Campylobacter
jejuni) 		4 / 4 LYS A  83
LEU A  30
ALA A  80
LEU A  75
 None
 1.47A 1f86B-3pj9A:
undetectable		 1f86B-3pj9A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_E_TFPE212_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3pj9 NUCLEOSIDE
DIPHOSPHATE KINASE
(Campylobacter
jejuni) 		4 / 7 PHE A 130
LEU A  22
PHE A 131
SER A 117
 SO4  A 139 ( 4.9A)
None
SO4  A 141 (-4.9A)
None
 1.16A 1wrlE-3pj9A:
undetectable		 1wrlE-3pj9A:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA472_1
(CYTOCHROME P450 51)		 3pj9 NUCLEOSIDE
DIPHOSPHATE KINASE
(Campylobacter
jejuni) 		4 / 6 MET A  65
VAL A  62
LEU A  61
PHE A  57
 None
 1.06A 1x8vA-3pj9A:
undetectable		 1x8vA-3pj9A:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3pj9 NUCLEOSIDE
DIPHOSPHATE KINASE
(Campylobacter
jejuni) 		5 / 12 GLY A  79
GLY A  77
GLY A  29
GLU A  76
VAL A  81
 None
 1.04A 2oxtC-3pj9A:
undetectable		 2oxtC-3pj9A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K36_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 3pj9 NUCLEOSIDE
DIPHOSPHATE KINASE
(Campylobacter
jejuni) 		5 / 12 TYR A  49
ASN A 122
SER A 117
LEU A   5
ILE A   7
 SO4  A 138 (-4.7A)
None
None
None
None
 1.41A 4k36A-3pj9A:
undetectable		 4k36A-3pj9A:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3pj9 NUCLEOSIDE
DIPHOSPHATE KINASE
(Campylobacter
jejuni) 		4 / 7 ILE A 101
ARG A  85
THR A   4
LEU A  75
 None
 0.98A 5zcpA-3pj9A:
undetectable
5zcpJ-3pj9A:
undetectable		 5zcpA-3pj9A:
13.33
5zcpJ-3pj9A:
22.94