SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pjx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_2
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
4 / 4 THR A 289
LEU A 293
VAL A 296
LEU A 300
None
0.72A 1fbmD-3pjxA:
undetectable
1fbmD-3pjxA:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GS4_A_ZK5A1918_1
(ANDROGEN RECEPTOR)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
5 / 12 LEU A 550
LEU A 553
GLY A 554
ALA A 578
LEU A 577
EDO  A   3 ( 4.8A)
None
None
EDO  A   3 ( 4.7A)
None
0.94A 1gs4A-3pjxA:
undetectable
1gs4A-3pjxA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI7_A_ID2A1_0
(THYMIDINE KINASE)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
5 / 12 GLU A 230
ILE A 600
TYR A 586
ALA A 606
ARG A 233
None
1.44A 1ki7A-3pjxA:
undetectable
1ki7A-3pjxA:
25.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_C_THAC3_1
(LIVER
CARBOXYLESTERASE I)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
5 / 12 LEU A 244
GLY A 297
THR A 354
LEU A 348
LEU A 345
None
1.19A 1mx1C-3pjxA:
undetectable
1mx1C-3pjxA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_1
(LIVER
CARBOXYLESTERASE I)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
5 / 12 LEU A 518
VAL A 514
LEU A 500
LEU A 505
LEU A 543
None
1.29A 1mx1E-3pjxA:
undetectable
1mx1E-3pjxA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
4 / 4 THR A 289
LEU A 293
VAL A 296
LEU A 300
None
0.63A 1mz9D-3pjxA:
undetectable
1mz9D-3pjxA:
8.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUA_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
5 / 10 ALA A 334
TYR A 268
LEU A 270
GLY A 363
GLY A 380
None
1.41A 1ruaH-3pjxA:
undetectable
1ruaL-3pjxA:
undetectable
1ruaH-3pjxA:
18.49
1ruaL-3pjxA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUL_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
5 / 9 ALA A 334
TYR A 268
LEU A 270
GLY A 363
GLY A 380
None
1.41A 1rulH-3pjxA:
undetectable
1rulL-3pjxA:
undetectable
1rulH-3pjxA:
18.49
1rulL-3pjxA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2888_0
(AMINOMETHYLTRANSFERA
SE)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
5 / 10 LEU A 557
LEU A 577
ILE A 587
GLU A 617
LEU A 580
EDO  A   3 (-4.5A)
None
None
None
None
1.25A 1wopA-3pjxA:
2.3
1wopA-3pjxA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_D_NCAD510_0
(NAD-DEPENDENT
DEACETYLASE 2)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
4 / 5 ALA A 358
ASN A 394
ILE A 362
ASP A 342
EDO  A   5 (-3.3A)
EDO  A   5 (-3.5A)
None
None
1.07A 1yc2D-3pjxA:
undetectable
1yc2D-3pjxA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_1
(ANDROGEN RECEPTOR)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
5 / 12 LEU A 550
LEU A 553
GLY A 554
ALA A 578
LEU A 577
EDO  A   3 ( 4.8A)
None
None
EDO  A   3 ( 4.7A)
None
0.85A 2oz7A-3pjxA:
undetectable
2oz7A-3pjxA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB928_0
(FERROCHELATASE)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
5 / 12 LEU A 271
LEU A 269
ARG A 318
PRO A 373
VAL A 258
None
1.20A 2qd4B-3pjxA:
undetectable
2qd4B-3pjxA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_A_DIFA1_1
(TRANSTHYRETIN)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
4 / 6 LEU A 364
ALA A 326
LEU A 270
THR A 310
None
0.91A 3cfqA-3pjxA:
undetectable
3cfqA-3pjxA:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IX9_B_MTXB200_1
(DIHYDROFOLATE
REDUCTASE)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
5 / 12 ILE A 603
GLU A 534
LEU A 559
GLN A 560
LYS A 581
None
1.08A 3ix9B-3pjxA:
undetectable
3ix9B-3pjxA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
3 / 3 ASN A 281
ASP A 290
ARG A 247
None
0.81A 3k13A-3pjxA:
4.1
3k13A-3pjxA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
5 / 12 GLY A 380
PHE A 367
LEU A 254
ARG A 257
GLU A 321
None
0.93A 3o7wA-3pjxA:
undetectable
3o7wA-3pjxA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_B_TCWB1126_1
(TRANSTHYRETIN)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
4 / 7 LEU A 269
ALA A 323
LEU A 325
THR A 315
None
0.73A 4d7bA-3pjxA:
undetectable
4d7bA-3pjxA:
13.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DM8_A_REAA501_1
(RETINOIC ACID
RECEPTOR BETA)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
5 / 11 PHE A 566
LEU A 614
LEU A 580
ILE A 582
ILE A 610
None
1.05A 4dm8A-3pjxA:
undetectable
4dm8A-3pjxA:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2O_B_CLQB1079_0
(SAPOSIN-B)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
3 / 3 MET A 329
GLU A 333
LEU A 337
None
0.80A 4v2oB-3pjxA:
undetectable
4v2oB-3pjxA:
10.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YJI_A_TYLA502_1
(ARYL ACYLAMIDASE)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
4 / 7 LEU A 572
GLY A 564
GLY A 563
ILE A 582
None
0.72A 4yjiA-3pjxA:
undetectable
4yjiA-3pjxA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
6 / 10 LEU A 546
THR A 504
LEU A 505
LEU A 500
LEU A 530
LEU A 550
None
None
None
None
None
EDO  A   3 ( 4.8A)
1.43A 4z91A-3pjxA:
undetectable
4z91B-3pjxA:
undetectable
4z91C-3pjxA:
1.9
4z91D-3pjxA:
undetectable
4z91E-3pjxA:
1.9
4z91A-3pjxA:
21.50
4z91B-3pjxA:
21.50
4z91C-3pjxA:
21.50
4z91D-3pjxA:
21.50
4z91E-3pjxA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
4 / 4 ALA A 616
PRO A 432
LEU A 496
HIS A 444
None
None
None
EDO  A 651 (-4.0A)
1.29A 5eskA-3pjxA:
undetectable
5eskA-3pjxA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_B_REAB602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
5 / 9 GLY A 576
THR A 547
LEU A 577
GLN A 225
LEU A 543
None
EDO  A   3 (-4.6A)
None
None
None
1.37A 5fhzB-3pjxA:
undetectable
5fhzB-3pjxA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGJ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
3 / 3 VAL A 442
VAL A 434
GLN A 431
EDO  A   2 (-4.4A)
None
None
0.66A 5qgjA-3pjxA:
undetectable
5qgjA-3pjxA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGJ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
3 / 3 VAL A 442
VAL A 434
GLN A 637
EDO  A   2 (-4.4A)
None
None
0.64A 5qgjA-3pjxA:
undetectable
5qgjA-3pjxA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGM_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
3 / 3 VAL A 442
VAL A 434
GLN A 431
EDO  A   2 (-4.4A)
None
None
0.64A 5qgmA-3pjxA:
undetectable
5qgmA-3pjxA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGN_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
3 / 3 VAL A 442
VAL A 434
GLN A 637
EDO  A   2 (-4.4A)
None
None
0.59A 5qgnA-3pjxA:
undetectable
5qgnA-3pjxA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGY_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
3 / 3 VAL A 442
VAL A 434
GLN A 637
EDO  A   2 (-4.4A)
None
None
0.57A 5qgyA-3pjxA:
undetectable
5qgyA-3pjxA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGZ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
3 / 3 VAL A 442
VAL A 434
GLN A 637
EDO  A   2 (-4.4A)
None
None
0.58A 5qgzA-3pjxA:
undetectable
5qgzA-3pjxA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH0_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
3 / 3 VAL A 442
VAL A 434
GLN A 637
EDO  A   2 (-4.4A)
None
None
0.58A 5qh0A-3pjxA:
undetectable
5qh0A-3pjxA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH2_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
3 / 3 VAL A 442
VAL A 434
GLN A 637
EDO  A   2 (-4.4A)
None
None
0.57A 5qh2A-3pjxA:
undetectable
5qh2A-3pjxA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH3_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
3 / 3 VAL A 442
VAL A 434
GLN A 637
EDO  A   2 (-4.4A)
None
None
0.59A 5qh3A-3pjxA:
undetectable
5qh3A-3pjxA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
3 / 3 VAL A 442
VAL A 434
GLN A 637
EDO  A   2 (-4.4A)
None
None
0.59A 5qh5A-3pjxA:
undetectable
5qh5A-3pjxA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
3 / 3 VAL A 442
VAL A 434
GLN A 431
EDO  A   2 (-4.4A)
None
None
0.67A 5qh6A-3pjxA:
undetectable
5qh6A-3pjxA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
3 / 3 VAL A 442
VAL A 434
GLN A 637
EDO  A   2 (-4.4A)
None
None
0.62A 5qh6A-3pjxA:
undetectable
5qh6A-3pjxA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH7_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
3 / 3 VAL A 442
VAL A 434
GLN A 637
EDO  A   2 (-4.4A)
None
None
0.59A 5qh7A-3pjxA:
undetectable
5qh7A-3pjxA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHA_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
3 / 3 VAL A 442
VAL A 434
GLN A 637
EDO  A   2 (-4.4A)
None
None
0.63A 5qhaA-3pjxA:
undetectable
5qhaA-3pjxA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
3 / 3 VAL A 442
VAL A 434
GLN A 637
EDO  A   2 (-4.4A)
None
None
0.59A 5qhhA-3pjxA:
undetectable
5qhhA-3pjxA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_C_SAMC201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
5 / 12 LEU A 272
ILE A 362
GLY A 363
LEU A 384
LEU A 300
None
1.00A 5twjC-3pjxA:
undetectable
5twjC-3pjxA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_D_SALD201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
4 / 5 PRO A 327
GLY A 267
VAL A 258
ARG A 257
None
1.33A 5x80C-3pjxA:
1.7
5x80D-3pjxA:
undetectable
5x80C-3pjxA:
17.70
5x80D-3pjxA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_V_BO2V301_0
(PROTEASOME SUBUNIT
BETA TYPE-2)
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens)
5 / 11 SER A 346
GLN A 299
GLY A 352
THR A 351
ALA A 350
None
1.09A 6hwdV-3pjxA:
undetectable
6hwdV-3pjxA:
13.37