SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3plr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMC_B_SAMB105_0
(MET REPRESSOR)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		5 / 10 ARG A 144
ARG A 147
GLU A  49
LEU A 149
GLY A  12
 None
 1.35A 1cmcA-3plrA:
undetectable
1cmcB-3plrA:
undetectable		 1cmcA-3plrA:
13.67
1cmcB-3plrA:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		4 / 5 TYR A 380
ILE A 291
ARG A 283
GLY A 248
 None
 1.13A 1kifA-3plrA:
4.5		 1kifA-3plrA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		4 / 5 TYR A 380
ILE A 364
ARG A 283
GLY A 248
 None
 1.30A 1kifA-3plrA:
4.5		 1kifA-3plrA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		4 / 5 TYR A 380
ILE A 291
ARG A 283
GLY A 248
 None
 1.13A 1kifB-3plrA:
4.5		 1kifB-3plrA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		4 / 5 TYR A 380
ILE A 364
ARG A 283
GLY A 248
 None
 1.30A 1kifB-3plrA:
4.5		 1kifB-3plrA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		4 / 5 TYR A 380
ILE A 291
ARG A 283
GLY A 248
 None
 1.13A 1kifC-3plrA:
4.5		 1kifC-3plrA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		4 / 5 TYR A 380
ILE A 364
ARG A 283
GLY A 248
 None
 1.30A 1kifC-3plrA:
4.5		 1kifC-3plrA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		4 / 5 TYR A 380
ILE A 291
ARG A 283
GLY A 248
 None
 1.13A 1kifD-3plrA:
4.4		 1kifD-3plrA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		4 / 5 TYR A 380
ILE A 364
ARG A 283
GLY A 248
 None
 1.30A 1kifD-3plrA:
4.4		 1kifD-3plrA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		4 / 5 TYR A 380
ILE A 291
ARG A 283
GLY A 248
 None
 1.13A 1kifE-3plrA:
4.4		 1kifE-3plrA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		4 / 5 TYR A 380
ILE A 364
ARG A 283
GLY A 248
 None
 1.30A 1kifE-3plrA:
4.4		 1kifE-3plrA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		4 / 5 TYR A 380
ILE A 291
ARG A 283
GLY A 248
 None
 1.13A 1kifF-3plrA:
4.5		 1kifF-3plrA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		4 / 5 TYR A 380
ILE A 364
ARG A 283
GLY A 248
 None
 1.30A 1kifF-3plrA:
4.5		 1kifF-3plrA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		4 / 5 TYR A 380
ILE A 291
ARG A 283
GLY A 248
 None
 1.12A 1kifG-3plrA:
4.5		 1kifG-3plrA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		4 / 5 TYR A 380
ILE A 364
ARG A 283
GLY A 248
 None
 1.30A 1kifG-3plrA:
4.5		 1kifG-3plrA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		4 / 5 TYR A 380
ILE A 291
ARG A 283
GLY A 248
 None
 1.12A 1kifH-3plrA:
4.3		 1kifH-3plrA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		4 / 5 TYR A 380
ILE A 364
ARG A 283
GLY A 248
 None
 1.30A 1kifH-3plrA:
4.3		 1kifH-3plrA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_A_NFZA1219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		4 / 8 PHE A 211
ASN A 212
GLY A 248
THR A 381
 None
 1.07A 1ykiA-3plrA:
undetectable
1ykiB-3plrA:
undetectable		 1ykiA-3plrA:
20.14
1ykiB-3plrA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_B_NFZB2219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		4 / 8 THR A 381
PHE A 211
ASN A 212
GLY A 248
 None
 1.05A 1ykiA-3plrA:
undetectable
1ykiB-3plrA:
undetectable		 1ykiA-3plrA:
20.14
1ykiB-3plrA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_C_NFZC3219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		4 / 8 PHE A 211
ASN A 212
GLY A 248
THR A 381
 None
 1.05A 1ykiC-3plrA:
undetectable
1ykiD-3plrA:
undetectable		 1ykiC-3plrA:
20.14
1ykiD-3plrA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_D_NFZD4219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		4 / 8 THR A 381
PHE A 211
ASN A 212
GLY A 248
 None
 1.07A 1ykiC-3plrA:
undetectable
1ykiD-3plrA:
undetectable		 1ykiC-3plrA:
20.14
1ykiD-3plrA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_C_H4BC1002_1
(HYPOTHETICAL PROTEIN
PH0634)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		4 / 6 ASP A 126
PHE A 123
THR A  94
GLU A  98
 None
 1.43A 2dttB-3plrA:
undetectable
2dttC-3plrA:
undetectable		 2dttB-3plrA:
15.57
2dttC-3plrA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		4 / 5 TYR A 380
ILE A 291
ARG A 283
GLY A 248
 None
 1.18A 2du8G-3plrA:
4.2		 2du8G-3plrA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		4 / 5 TYR A 380
ILE A 364
ARG A 283
GLY A 248
 None
 1.32A 2du8G-3plrA:
4.2		 2du8G-3plrA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		4 / 5 TYR A 380
ILE A 291
ARG A 283
GLY A 248
 None
 1.19A 2du8J-3plrA:
4.1		 2du8J-3plrA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		4 / 5 TYR A 380
ILE A 364
ARG A 283
GLY A 248
 None
 1.33A 2du8J-3plrA:
4.1		 2du8J-3plrA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_E_SAME1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A  16
GLY A  12
ILE A   3
ALA A  20
GLU A 141
 None
 1.06A 2vdvE-3plrA:
4.6		 2vdvE-3plrA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_F_SAMF1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		5 / 11 GLY A  16
GLY A  12
ILE A   3
ALA A  20
GLU A 141
 None
 1.06A 2vdvF-3plrA:
5.2		 2vdvF-3plrA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRH_A_NIOA200_1
(PROTEIN HP0721)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		4 / 7 GLY A 132
ILE A 127
THR A 124
MET A 113
 None
 0.96A 2xrhA-3plrA:
undetectable		 2xrhA-3plrA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM8_A_ACAA511_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		4 / 8 TYR A 210
ILE A 238
ILE A 229
HIS A 241
 None
 1.02A 2zm8A-3plrA:
undetectable		 2zm8A-3plrA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMA_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		4 / 8 TYR A 210
ILE A 238
ILE A 229
HIS A 241
 None
 1.01A 2zmaA-3plrA:
undetectable		 2zmaA-3plrA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_C_P77C203_1
(PROTEIN S100-A4)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		5 / 10 SER A 317
PHE A 211
ILE A 229
LEU A 384
ASP A 383
 None
 1.45A 3m0wC-3plrA:
undetectable
3m0wD-3plrA:
undetectable
3m0wE-3plrA:
undetectable
3m0wF-3plrA:
undetectable		 3m0wC-3plrA:
15.32
3m0wD-3plrA:
15.32
3m0wE-3plrA:
15.32
3m0wF-3plrA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_H_P77H203_1
(PROTEIN S100-A4)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		5 / 10 LEU A 384
ASP A 383
PHE A 211
ILE A 229
SER A 317
 None
 1.41A 3m0wE-3plrA:
undetectable
3m0wF-3plrA:
undetectable
3m0wG-3plrA:
undetectable
3m0wH-3plrA:
undetectable		 3m0wE-3plrA:
15.32
3m0wF-3plrA:
15.32
3m0wG-3plrA:
15.32
3m0wH-3plrA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_I_P77I203_1
(PROTEIN S100-A4)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		5 / 10 LEU A 384
ASP A 383
PHE A 211
ILE A 229
SER A 317
 None
 1.44A 3m0wA-3plrA:
undetectable
3m0wB-3plrA:
undetectable
3m0wI-3plrA:
undetectable
3m0wJ-3plrA:
undetectable		 3m0wA-3plrA:
15.32
3m0wB-3plrA:
15.32
3m0wI-3plrA:
15.32
3m0wJ-3plrA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_B_CGEB501_1
(CYTOCHROME P450 2B4)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		4 / 8 PHE A 247
ILE A 318
ALA A 288
VAL A 299
 None
 0.88A 3me6B-3plrA:
undetectable		 3me6B-3plrA:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_C_CGEC501_1
(CYTOCHROME P450 2B4)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		5 / 9 PHE A 247
ILE A 318
ALA A 288
VAL A 332
VAL A 301
 None
 1.20A 3me6C-3plrA:
undetectable		 3me6C-3plrA:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_C_OBNC1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		5 / 11 PRO A 155
ASN A 152
LEU A 149
VAL A  17
ALA A  20
 None
 1.36A 3n23C-3plrA:
undetectable		 3n23C-3plrA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		6 / 12 HIS A  23
LEU A 174
PHE A 170
ILE A  19
SER A  14
LEU A 149
 None
 1.30A 3n8xB-3plrA:
undetectable		 3n8xB-3plrA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_C_ZPCC1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		5 / 12 PHE A 170
ILE A   5
ASN A  15
ILE A 183
VAL A  25
 None
 1.33A 4a97B-3plrA:
undetectable
4a97C-3plrA:
undetectable		 4a97B-3plrA:
20.56
4a97C-3plrA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 248
GLY A 250
ILE A 318
ILE A 321
SER A 246
 None
U5P  A 901 (-3.2A)
None
None
U5P  A 901 (-2.8A)
 1.13A 4iv0B-3plrA:
4.8		 4iv0B-3plrA:
25.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_A_FUAA1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		4 / 5 ILE A 364
LYS A 328
ILE A 330
VAL A 332
 None
 0.89A 5jmnA-3plrA:
undetectable		 5jmnA-3plrA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_F_Z80F401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		5 / 10 ILE A 101
ILE A 127
VAL A  97
THR A  94
ILE A 119
 None
 1.20A 5lg3F-3plrA:
0.8		 5lg3F-3plrA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_G_Z80G401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		5 / 10 ILE A 101
ILE A 127
VAL A  97
THR A  94
ILE A 119
 None
 1.21A 5lg3G-3plrA:
undetectable		 5lg3G-3plrA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_H_Z80H401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		5 / 10 ILE A 101
ILE A 127
VAL A  97
THR A  94
ILE A 119
 None
 1.17A 5lg3H-3plrA:
undetectable		 5lg3H-3plrA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_J_Z80J401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		5 / 12 ILE A 101
ILE A 127
VAL A  97
THR A  94
ILE A 119
 None
 1.22A 5lg3J-3plrA:
undetectable		 5lg3J-3plrA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB308_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		3 / 3 LEU A 206
ILE A 276
TYR A 265
 None
 0.61A 5uunB-3plrA:
undetectable		 5uunB-3plrA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A4I_A_TRPA403_0
(TRYPTOPHAN
2,3-DIOXYGENASE)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		4 / 8 ARG A 125
THR A 124
ILE A 119
PRO A 120
 None
 1.11A 6a4iA-3plrA:
undetectable		 6a4iA-3plrA:
24.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_B_9SCB601_0
(SERUM ALBUMIN)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		5 / 12 ILE A 276
VAL A 301
LEU A 304
ALA A 205
PHE A 247
 None
 1.41A 6a7pB-3plrA:
undetectable		 6a7pB-3plrA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_A_SAMA501_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 3plr UDP-GLUCOSE
6-DEHYDROGENASE
(Klebsiella
pneumoniae) 		5 / 12 ILE A 318
ILE A 334
ILE A 291
VAL A 362
ILE A 364
 None
 1.01A 6emuA-3plrA:
2.2		 6emuA-3plrA:
22.38