SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3plt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_1
(METHYLTRANSFERASE
NSUN4)		 3plt SPHINGOLIPID LONG
CHAIN
BASE-RESPONSIVE
PROTEIN LSP1
(Saccharomyces
cerevisiae) 		3 / 3 ASP A 123
ARG A 126
ASP A 116
 None
 0.73A 4fp9A-3pltA:
undetectable		 4fp9A-3pltA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_1
(METHYLTRANSFERASE
NSUN4)		 3plt SPHINGOLIPID LONG
CHAIN
BASE-RESPONSIVE
PROTEIN LSP1
(Saccharomyces
cerevisiae) 		3 / 3 ASP A 123
ARG A 126
ASP A 116
 None
 0.75A 4fp9C-3pltA:
undetectable		 4fp9C-3pltA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_1
(METHYLTRANSFERASE
NSUN4)		 3plt SPHINGOLIPID LONG
CHAIN
BASE-RESPONSIVE
PROTEIN LSP1
(Saccharomyces
cerevisiae) 		3 / 3 ASP A 123
ARG A 126
ASP A 116
 None
 0.78A 4fp9F-3pltA:
undetectable		 4fp9F-3pltA:
21.76