SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pm0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_B_ACTB704_0
(FUMARATE REDUCTASE
FLAVOPROTEIN
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		3 / 3 ARG A 368
GLY A 373
ASP A 374
 None
 0.59A 1kf6A-3pm0A:
undetectable
1kf6B-3pm0A:
undetectable		 1kf6A-3pm0A:
21.77
1kf6B-3pm0A:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_L_AG2L7014_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		4 / 7 LEU A 482
LEU A 475
MET A 372
GLU A 167
 None
HEM  A 900 ( 4.9A)
None
None
 1.07A 1n13I-3pm0A:
undetectable
1n13L-3pm0A:
undetectable		 1n13I-3pm0A:
7.82
1n13L-3pm0A:
10.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NR6_A_DIFA501_1
(CYTOCHROME P450 2C5)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		5 / 9 ALA A 133
PHE A 134
GLY A 329
ALA A 330
THR A 334
 HEM  A 900 (-3.3A)
BHF  A 800 (-4.8A)
BHF  A 800 ( 4.0A)
HEM  A 900 ( 3.4A)
HEM  A 900 ( 3.2A)
 0.80A 1nr6A-3pm0A:
41.5		 1nr6A-3pm0A:
35.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		6 / 12 ILE A 324
ALA A 322
LEU A 315
PHE A 296
ILE A 471
ILE A 327
 None
None
None
None
HEM  A 900 (-4.3A)
HEM  A 900 (-4.1A)
 1.32A 1rx2A-3pm0A:
undetectable		 1rx2A-3pm0A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V3Q_E_2DIE290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		5 / 10 VAL A 235
GLY A 232
ASN A 265
VAL A 126
HIS A 227
 None
 1.32A 1v3qE-3pm0A:
undetectable		 1v3qE-3pm0A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD36_0
(GCN4 LEUCINE ZIPPER)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		3 / 3 SER A 138
TYR A 137
HIS A 136
 None
 0.76A 2r2vD-3pm0A:
undetectable		 2r2vD-3pm0A:
4.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_1
(NON-STRUCTURAL
PROTEIN 5)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		3 / 3 SER A 336
HIS A 169
ASP A 291
 None
 0.75A 2wa2B-3pm0A:
undetectable		 2wa2B-3pm0A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		5 / 10 ILE A 327
GLY A 472
LEU A 166
MET A 292
MET A 205
 HEM  A 900 (-4.1A)
HEM  A 900 ( 4.0A)
None
None
None
 1.42A 3adsA-3pm0A:
undetectable		 3adsA-3pm0A:
20.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3E4E_A_4PZA501_1
(CYTOCHROME P450 2E1)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		3 / 3 ALA A 330
THR A 334
CYH A 470
 HEM  A 900 ( 3.4A)
HEM  A 900 ( 3.2A)
HEM  A 900 (-2.3A)
 0.50A 3e4eA-3pm0A:
41.8		 3e4eA-3pm0A:
33.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3E4E_B_4PZB501_1
(CYTOCHROME P450 2E1)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		3 / 3 ALA A 330
THR A 334
CYH A 470
 HEM  A 900 ( 3.4A)
HEM  A 900 ( 3.2A)
HEM  A 900 (-2.3A)
 0.41A 3e4eB-3pm0A:
41.8		 3e4eB-3pm0A:
33.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KM6_B_EAAB222_1
(GLUTATHIONE
S-TRANSFERASE P)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		5 / 9 VAL A  96
VAL A 409
GLN A 105
VAL A 427
ASN A 423
 None
 1.39A 3km6B-3pm0A:
undetectable		 3km6B-3pm0A:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		6 / 12 ALA A 133
ASP A 326
ALA A 330
THR A 334
VAL A 395
CYH A 470
 HEM  A 900 (-3.3A)
BHF  A 800 (-3.4A)
HEM  A 900 ( 3.4A)
HEM  A 900 ( 3.2A)
HEM  A 900 (-4.6A)
HEM  A 900 (-2.3A)
 0.75A 3rukA-3pm0A:
41.4		 3rukA-3pm0A:
29.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		5 / 12 ALA A 133
PHE A 134
ASN A 228
ALA A 330
CYH A 470
 HEM  A 900 (-3.3A)
BHF  A 800 (-4.8A)
BHF  A 800 (-4.2A)
HEM  A 900 ( 3.4A)
HEM  A 900 (-2.3A)
 0.92A 3rukA-3pm0A:
41.4		 3rukA-3pm0A:
29.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		6 / 12 ALA A 133
PHE A 134
ASP A 326
ALA A 330
THR A 334
CYH A 470
 HEM  A 900 (-3.3A)
BHF  A 800 (-4.8A)
BHF  A 800 (-3.4A)
HEM  A 900 ( 3.4A)
HEM  A 900 ( 3.2A)
HEM  A 900 (-2.3A)
 0.54A 3rukA-3pm0A:
41.4		 3rukA-3pm0A:
29.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		6 / 12 ALA A 133
PHE A 134
ASP A 326
GLY A 329
ALA A 330
THR A 334
 HEM  A 900 (-3.3A)
BHF  A 800 (-4.8A)
BHF  A 800 (-3.4A)
BHF  A 800 ( 4.0A)
HEM  A 900 ( 3.4A)
HEM  A 900 ( 3.2A)
 0.52A 3rukB-3pm0A:
41.4		 3rukB-3pm0A:
29.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		6 / 11 ALA A 133
ASP A 326
GLY A 329
ALA A 330
THR A 334
VAL A 395
 HEM  A 900 (-3.3A)
BHF  A 800 (-3.4A)
BHF  A 800 ( 4.0A)
HEM  A 900 ( 3.4A)
HEM  A 900 ( 3.2A)
HEM  A 900 (-4.6A)
 0.69A 3rukD-3pm0A:
41.1		 3rukD-3pm0A:
29.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		6 / 11 ALA A 133
PHE A 134
ASP A 326
GLY A 329
ALA A 330
THR A 334
 HEM  A 900 (-3.3A)
BHF  A 800 (-4.8A)
BHF  A 800 (-3.4A)
BHF  A 800 ( 4.0A)
HEM  A 900 ( 3.4A)
HEM  A 900 ( 3.2A)
 0.56A 3rukD-3pm0A:
41.1		 3rukD-3pm0A:
29.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		4 / 4 LEU A 509
GLY A 508
GLY A 236
THR A 234
 BHF  A 800 (-4.7A)
None
None
None
 0.89A 3si7A-3pm0A:
undetectable		 3si7A-3pm0A:
20.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3T3S_D_9PLD1_1
(CYTOCHROME P450 2A13)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		4 / 8 ALA A 133
PHE A 134
ALA A 330
THR A 334
 HEM  A 900 (-3.3A)
BHF  A 800 (-4.8A)
HEM  A 900 ( 3.4A)
HEM  A 900 ( 3.2A)
 0.58A 3t3sD-3pm0A:
40.6		 3t3sD-3pm0A:
33.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_A_ZPCA1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		4 / 7 TYR A 214
VAL A 199
ARG A 213
ASN A 203
 None
 1.05A 4a97E-3pm0A:
undetectable		 4a97E-3pm0A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		4 / 8 TYR A 214
VAL A 199
ARG A 213
ASN A 203
 None
 1.07A 4a97G-3pm0A:
undetectable		 4a97G-3pm0A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_I_ZPCI1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		4 / 7 TYR A 214
VAL A 199
ARG A 213
ASN A 203
 None
 1.12A 4a97H-3pm0A:
undetectable		 4a97H-3pm0A:
20.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EJJ_A_NCTA501_1
(CYTOCHROME P450 2A6)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		4 / 7 ASN A 228
GLY A 232
ILE A 399
PHE A 134
 BHF  A 800 (-4.2A)
None
HEM  A 900 (-4.0A)
BHF  A 800 (-4.8A)
 0.79A 4ejjA-3pm0A:
41.3		 4ejjA-3pm0A:
32.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_0U9A601_1
(CHOLESTEROL
24-HYDROXYLASE)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		5 / 12 PHE A 268
PHE A 134
VAL A 235
ALA A 330
THR A 334
 BHF  A 800 ( 3.8A)
BHF  A 800 (-4.8A)
None
HEM  A 900 ( 3.4A)
HEM  A 900 ( 3.2A)
 1.28A 4fiaA-3pm0A:
34.3		 4fiaA-3pm0A:
25.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_198A602_1
(CHOLESTEROL
24-HYDROXYLASE)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		5 / 12 PHE A 268
PHE A 134
VAL A 235
ALA A 330
THR A 334
 BHF  A 800 ( 3.8A)
BHF  A 800 (-4.8A)
None
HEM  A 900 ( 3.4A)
HEM  A 900 ( 3.2A)
 1.28A 4fiaA-3pm0A:
34.3		 4fiaA-3pm0A:
25.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		5 / 12 ALA A 133
PHE A 134
GLY A 329
ALA A 330
THR A 334
 HEM  A 900 (-3.3A)
BHF  A 800 (-4.8A)
BHF  A 800 ( 4.0A)
HEM  A 900 ( 3.4A)
HEM  A 900 ( 3.2A)
 0.48A 4nkvA-3pm0A:
41.2		 4nkvA-3pm0A:
29.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		5 / 12 ALA A 133
PHE A 134
GLY A 329
ALA A 330
THR A 334
 HEM  A 900 (-3.3A)
BHF  A 800 (-4.8A)
BHF  A 800 ( 4.0A)
HEM  A 900 ( 3.4A)
HEM  A 900 ( 3.2A)
 0.47A 4nkvB-3pm0A:
41.0		 4nkvB-3pm0A:
29.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_C_AERC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		5 / 12 ALA A 133
PHE A 134
GLY A 329
ALA A 330
THR A 334
 HEM  A 900 (-3.3A)
BHF  A 800 (-4.8A)
BHF  A 800 ( 4.0A)
HEM  A 900 ( 3.4A)
HEM  A 900 ( 3.2A)
 0.50A 4nkvC-3pm0A:
41.3		 4nkvC-3pm0A:
29.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		5 / 12 ALA A 133
PHE A 134
GLY A 329
ALA A 330
THR A 334
 HEM  A 900 (-3.3A)
BHF  A 800 (-4.8A)
BHF  A 800 ( 4.0A)
HEM  A 900 ( 3.4A)
HEM  A 900 ( 3.2A)
 0.51A 4nkvD-3pm0A:
41.5		 4nkvD-3pm0A:
29.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		6 / 12 ALA A 133
PHE A 134
GLY A 329
ALA A 330
THR A 334
ILE A 399
 HEM  A 900 (-3.3A)
BHF  A 800 (-4.8A)
BHF  A 800 ( 4.0A)
HEM  A 900 ( 3.4A)
HEM  A 900 ( 3.2A)
HEM  A 900 (-4.0A)
 0.45A 4nkxA-3pm0A:
41.0		 4nkxA-3pm0A:
29.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		6 / 12 ALA A 133
PHE A 134
GLY A 329
ALA A 330
THR A 334
ILE A 399
 HEM  A 900 (-3.3A)
BHF  A 800 (-4.8A)
BHF  A 800 ( 4.0A)
HEM  A 900 ( 3.4A)
HEM  A 900 ( 3.2A)
HEM  A 900 (-4.0A)
 0.51A 4nkxC-3pm0A:
41.5		 4nkxC-3pm0A:
29.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		6 / 12 ALA A 133
PHE A 134
GLY A 329
ALA A 330
THR A 334
ILE A 399
 HEM  A 900 (-3.3A)
BHF  A 800 (-4.8A)
BHF  A 800 ( 4.0A)
HEM  A 900 ( 3.4A)
HEM  A 900 ( 3.2A)
HEM  A 900 (-4.0A)
 0.47A 4nkxD-3pm0A:
41.5		 4nkxD-3pm0A:
29.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R1Z_A_AERA601_1
(CYP17A1 PROTEIN)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		5 / 9 ALA A 133
ASP A 326
GLY A 329
ALA A 330
THR A 334
 HEM  A 900 (-3.3A)
BHF  A 800 (-3.4A)
BHF  A 800 ( 4.0A)
HEM  A 900 ( 3.4A)
HEM  A 900 ( 3.2A)
 0.40A 4r1zA-3pm0A:
41.5		 4r1zA-3pm0A:
31.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R1Z_B_AERB601_1
(CYP17A1 PROTEIN)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		4 / 7 ALA A 133
GLY A 329
ALA A 330
THR A 334
 HEM  A 900 (-3.3A)
BHF  A 800 ( 4.0A)
HEM  A 900 ( 3.4A)
HEM  A 900 ( 3.2A)
 0.32A 4r1zB-3pm0A:
41.0		 4r1zB-3pm0A:
31.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R21_B_STRB601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		5 / 9 ALA A 133
GLY A 329
ALA A 330
THR A 334
ILE A 399
 HEM  A 900 (-3.3A)
BHF  A 800 ( 4.0A)
HEM  A 900 ( 3.4A)
HEM  A 900 ( 3.2A)
HEM  A 900 (-4.0A)
 0.50A 4r21B-3pm0A:
41.6		 4r21B-3pm0A:
34.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_2
(TUBULIN BETA CHAIN)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		5 / 12 LEU A 480
LEU A 487
ALA A 200
VAL A 170
ALA A 174
 None
 1.10A 4x1kD-3pm0A:
undetectable		 4x1kD-3pm0A:
21.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XXI_A_LSNA503_1
(CYTOCHROME P450 2C9)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		5 / 12 ILE A  94
PHE A 120
PHE A 134
PRO A 396
PRO A 400
 None
None
BHF  A 800 (-4.8A)
None
None
 1.15A 5xxiA-3pm0A:
38.4		 5xxiA-3pm0A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DWN_A_AQ4A602_0
(CYTOCHROME P450 1A1)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		5 / 12 ASN A 228
PHE A 231
PHE A 268
ASP A 326
GLY A 329
 BHF  A 800 (-4.2A)
BHF  A 800 (-3.4A)
BHF  A 800 ( 3.8A)
BHF  A 800 (-3.4A)
BHF  A 800 ( 4.0A)
 1.19A 6dwnA-3pm0A:
48.0		 6dwnA-3pm0A:
58.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DWN_A_AQ4A602_0
(CYTOCHROME P450 1A1)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		7 / 12 PHE A 231
ASN A 265
PHE A 268
ASP A 326
GLY A 329
ASP A 333
ILE A 399
 BHF  A 800 (-3.4A)
None
BHF  A 800 ( 3.8A)
BHF  A 800 (-3.4A)
BHF  A 800 ( 4.0A)
BHF  A 800 ( 4.1A)
HEM  A 900 (-4.0A)
 0.62A 6dwnA-3pm0A:
48.0		 6dwnA-3pm0A:
58.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DWN_A_AQ4A602_1
(CYTOCHROME P450 1A1)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		4 / 5 SER A 127
ALA A 330
LEU A 509
LYS A 512
 BHF  A 800 ( 4.6A)
HEM  A 900 ( 3.4A)
BHF  A 800 (-4.7A)
None
 0.77A 6dwnA-3pm0A:
48.0		 6dwnA-3pm0A:
58.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DWN_B_AQ4B602_0
(CYTOCHROME P450 1A1)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		7 / 12 PHE A 231
ASN A 265
PHE A 268
ASP A 326
ASP A 333
ILE A 399
LYS A 512
 BHF  A 800 (-3.4A)
None
BHF  A 800 ( 3.8A)
BHF  A 800 (-3.4A)
BHF  A 800 ( 4.1A)
HEM  A 900 (-4.0A)
None
 0.81A 6dwnB-3pm0A:
48.1		 6dwnB-3pm0A:
58.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DWN_B_AQ4B602_0
(CYTOCHROME P450 1A1)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		5 / 12 SER A 131
LEU A 224
ASP A 326
ASP A 333
LYS A 512
 BHF  A 800 ( 4.7A)
None
BHF  A 800 (-3.4A)
BHF  A 800 ( 4.1A)
None
 1.43A 6dwnB-3pm0A:
48.1		 6dwnB-3pm0A:
58.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DWN_B_AQ4B602_1
(CYTOCHROME P450 1A1)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		6 / 7 SER A 127
PHE A 261
GLY A 329
ALA A 330
VAL A 395
LEU A 509
 BHF  A 800 ( 4.6A)
None
BHF  A 800 ( 4.0A)
HEM  A 900 ( 3.4A)
HEM  A 900 (-4.6A)
BHF  A 800 (-4.7A)
 0.55A 6dwnB-3pm0A:
48.1		 6dwnB-3pm0A:
58.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DWN_C_AQ4C602_0
(CYTOCHROME P450 1A1)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		6 / 12 ASN A 228
PHE A 231
PHE A 268
ASP A 326
GLY A 329
LEU A 509
 BHF  A 800 (-4.2A)
BHF  A 800 (-3.4A)
BHF  A 800 ( 3.8A)
BHF  A 800 (-3.4A)
BHF  A 800 ( 4.0A)
BHF  A 800 (-4.7A)
 1.11A 6dwnC-3pm0A:
48.2		 6dwnC-3pm0A:
58.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DWN_C_AQ4C602_0
(CYTOCHROME P450 1A1)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		7 / 12 PHE A 231
ASN A 265
PHE A 268
ASP A 326
GLY A 329
ILE A 399
LEU A 509
 BHF  A 800 (-3.4A)
None
BHF  A 800 ( 3.8A)
BHF  A 800 (-3.4A)
BHF  A 800 ( 4.0A)
HEM  A 900 (-4.0A)
BHF  A 800 (-4.7A)
 0.65A 6dwnC-3pm0A:
48.2		 6dwnC-3pm0A:
58.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DWN_C_AQ4C602_1
(CYTOCHROME P450 1A1)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		3 / 3 SER A 127
SER A 131
ALA A 330
 BHF  A 800 ( 4.6A)
BHF  A 800 ( 4.7A)
HEM  A 900 ( 3.4A)
 0.62A 6dwnC-3pm0A:
48.2		 6dwnC-3pm0A:
58.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DWN_D_AQ4D602_0
(CYTOCHROME P450 1A1)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		6 / 12 ASN A 228
PHE A 231
PHE A 268
ASP A 326
GLY A 329
LEU A 509
 BHF  A 800 (-4.2A)
BHF  A 800 (-3.4A)
BHF  A 800 ( 3.8A)
BHF  A 800 (-3.4A)
BHF  A 800 ( 4.0A)
BHF  A 800 (-4.7A)
 1.26A 6dwnD-3pm0A:
46.9		 6dwnD-3pm0A:
58.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DWN_D_AQ4D602_0
(CYTOCHROME P450 1A1)		 3pm0 CYTOCHROME P450 1B1
(Homo
sapiens) 		8 / 12 PHE A 231
PHE A 268
ASP A 326
GLY A 329
ALA A 330
ASP A 333
ILE A 399
LEU A 509
 BHF  A 800 (-3.4A)
BHF  A 800 ( 3.8A)
BHF  A 800 (-3.4A)
BHF  A 800 ( 4.0A)
HEM  A 900 ( 3.4A)
BHF  A 800 ( 4.1A)
HEM  A 900 (-4.0A)
BHF  A 800 (-4.7A)
 0.71A 6dwnD-3pm0A:
46.9		 6dwnD-3pm0A:
58.75