SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pm9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_C_DESC500_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3pm9 PUTATIVE
OXIDOREDUCTASE
(Rhodopseudomonas
palustris) 		5 / 12 LEU A 247
LEU A 244
ALA A 243
LEU A 263
ILE A 308
 None
 1.05A 1s9pC-3pm9A:
undetectable		 1s9pC-3pm9A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_C_REAC503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3pm9 PUTATIVE
OXIDOREDUCTASE
(Rhodopseudomonas
palustris) 		5 / 10 ALA A 332
GLN A 329
PHE A 234
ALA A 324
ILE A 340
 None
 1.05A 2aclC-3pm9A:
undetectable		 2aclC-3pm9A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3pm9 PUTATIVE
OXIDOREDUCTASE
(Rhodopseudomonas
palustris) 		4 / 5 ASP A 315
GLY A 248
VAL A 318
ILE A 317
 None
 0.96A 2aoiA-3pm9A:
undetectable		 2aoiA-3pm9A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_B_FUAB2002_1
(SERUM ALBUMIN)		 3pm9 PUTATIVE
OXIDOREDUCTASE
(Rhodopseudomonas
palustris) 		4 / 9 ILE A 215
VAL A  63
CYH A  67
LYS A  68
 FAD  A 476 (-4.6A)
None
None
None
 0.94A 2vufB-3pm9A:
undetectable		 2vufB-3pm9A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 3pm9 PUTATIVE
OXIDOREDUCTASE
(Rhodopseudomonas
palustris) 		5 / 12 ILE A 468
ASN A 470
GLY A 214
GLY A 211
LEU A 181
 None
FAD  A 476 (-4.0A)
None
FAD  A 476 (-3.2A)
None
 0.98A 2zw9A-3pm9A:
undetectable		 2zw9A-3pm9A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3pm9 PUTATIVE
OXIDOREDUCTASE
(Rhodopseudomonas
palustris) 		5 / 9 ILE A 468
MET A 469
LEU A  77
ILE A  99
ILE A 215
 None
None
None
None
FAD  A 476 (-4.6A)
 1.07A 3zosA-3pm9A:
undetectable		 3zosA-3pm9A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3pm9 PUTATIVE
OXIDOREDUCTASE
(Rhodopseudomonas
palustris) 		4 / 5 GLY A  88
GLY A  89
ASN A 470
GLU A  42
 None
FAD  A 476 (-3.7A)
FAD  A 476 (-4.0A)
None
 1.16A 4fglC-3pm9A:
undetectable		 4fglC-3pm9A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTV_C_ADNC403_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3pm9 PUTATIVE
OXIDOREDUCTASE
(Rhodopseudomonas
palustris) 		5 / 11 HIS A 387
ASP A 390
SER A 429
ILE A 355
ASP A 354
 UNL  A 477 ( 3.7A)
None
None
None
None
 1.32A 4ktvC-3pm9A:
undetectable
4ktvD-3pm9A:
undetectable		 4ktvC-3pm9A:
23.40
4ktvD-3pm9A:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_B_AERB602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 3pm9 PUTATIVE
OXIDOREDUCTASE
(Rhodopseudomonas
palustris) 		5 / 9 ALA A 265
ASN A 392
ILE A 355
GLY A 386
VAL A 362
 None
UNL  A 477 ( 4.6A)
None
None
None
 1.16A 4r20B-3pm9A:
undetectable		 4r20B-3pm9A:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJO_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3pm9 PUTATIVE
OXIDOREDUCTASE
(Rhodopseudomonas
palustris) 		5 / 11 SER A 156
THR A 157
GLU A  42
THR A 150
GLY A  82
 FAD  A 476 (-2.8A)
FAD  A 476 (-3.2A)
None
FAD  A 476 (-3.1A)
FAD  A 476 (-3.3A)
 1.40A 4zjoD-3pm9A:
6.0		 4zjoD-3pm9A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_B_SAMB304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 3pm9 PUTATIVE
OXIDOREDUCTASE
(Rhodopseudomonas
palustris) 		5 / 10 LEU A 258
GLY A 389
ILE A 249
LEU A 246
LEU A 244
 None
 1.00A 5l0zB-3pm9A:
undetectable		 5l0zB-3pm9A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_A_ACTA803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 3pm9 PUTATIVE
OXIDOREDUCTASE
(Rhodopseudomonas
palustris) 		4 / 4 GLU A  15
PRO A  14
ILE A  17
LEU A  16
 None
 1.14A 5m45A-3pm9A:
1.7		 5m45A-3pm9A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_G_ACTG803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 3pm9 PUTATIVE
OXIDOREDUCTASE
(Rhodopseudomonas
palustris) 		4 / 4 GLU A  15
PRO A  14
ILE A  17
LEU A  16
 None
 1.11A 5m45G-3pm9A:
undetectable		 5m45G-3pm9A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_J_ACTJ803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 3pm9 PUTATIVE
OXIDOREDUCTASE
(Rhodopseudomonas
palustris) 		4 / 4 GLU A  15
PRO A  14
ILE A  17
LEU A  16
 None
 1.13A 5m45J-3pm9A:
undetectable		 5m45J-3pm9A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_A_PFLA511_1
(PROTON-GATED ION
CHANNEL)		 3pm9 PUTATIVE
OXIDOREDUCTASE
(Rhodopseudomonas
palustris) 		4 / 8 ILE A 207
ALA A 170
ILE A 151
ALA A 219
 None
 0.76A 5mvmA-3pm9A:
undetectable
5mvmB-3pm9A:
undetectable		 5mvmA-3pm9A:
10.08
5mvmB-3pm9A:
10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZJ_A_TEPA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 3pm9 PUTATIVE
OXIDOREDUCTASE
(Rhodopseudomonas
palustris) 		4 / 8 LEU A  12
PHE A  20
LEU A  77
ILE A  99
 None
 0.90A 5mzjA-3pm9A:
undetectable		 5mzjA-3pm9A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A60_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3pm9 PUTATIVE
OXIDOREDUCTASE
(Rhodopseudomonas
palustris) 		5 / 12 ALA A 332
GLN A 329
PHE A 234
ALA A 324
ILE A 340
 None
 1.04A 6a60D-3pm9A:
undetectable		 6a60D-3pm9A:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXL_A_SAMA401_0
(2-(3-AMINO-3-CARBOXY
PROPYL)HISTIDINE
SYNTHASE)		 3pm9 PUTATIVE
OXIDOREDUCTASE
(Rhodopseudomonas
palustris) 		5 / 12 GLY A 386
HIS A 387
SER A 398
GLN A 344
ASP A 354
 None
UNL  A 477 ( 3.7A)
None
PO4  A 490 (-2.9A)
None
 1.49A 6bxlA-3pm9A:
undetectable		 6bxlA-3pm9A:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA816_0
(UNCHARACTERIZED
PROTEIN)		 3pm9 PUTATIVE
OXIDOREDUCTASE
(Rhodopseudomonas
palustris) 		3 / 3 ARG A 171
ARG A 203
ASP A 204
 None
 0.81A 6d8pA-3pm9A:
undetectable		 6d8pA-3pm9A:
20.60