SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pmc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3pmc UNCHARACTERIZED
PROTEIN
PXO2-61/BXB0075/GBAA
_PXO2_0075
(Bacillus
anthracis) 		5 / 12 PHE A  50
ASN A  97
ILE A  98
LEU A   8
VAL A 113
 None
 1.00A 4nkvB-3pmcA:
undetectable		 4nkvB-3pmcA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_A_VORA590_1
(14-ALPHA STEROL
DEMETHYLASE)		 3pmc UNCHARACTERIZED
PROTEIN
PXO2-61/BXB0075/GBAA
_PXO2_0075
(Bacillus
anthracis) 		4 / 7 PHE A 120
ALA A  91
LEU A  12
PHE A  19
 None
 1.02A 4uymA-3pmcA:
undetectable		 4uymA-3pmcA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_B_VORB590_1
(14-ALPHA STEROL
DEMETHYLASE)		 3pmc UNCHARACTERIZED
PROTEIN
PXO2-61/BXB0075/GBAA
_PXO2_0075
(Bacillus
anthracis) 		4 / 7 PHE A 120
ALA A  91
LEU A  12
PHE A  19
 None
 1.01A 4uymB-3pmcA:
1.2		 4uymB-3pmcA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OS7_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3pmc UNCHARACTERIZED
PROTEIN
PXO2-61/BXB0075/GBAA
_PXO2_0075
(Bacillus
anthracis) 		3 / 3 HIS A 129
SER A 130
LYS A  68
 None
IOD  A 413 (-3.2A)
IOD  A 413 (-2.6A)
 1.44A 5os7A-3pmcA:
undetectable		 5os7A-3pmcA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3pmc UNCHARACTERIZED
PROTEIN
PXO2-61/BXB0075/GBAA
_PXO2_0075
(Bacillus
anthracis) 		3 / 3 ASN A  80
VAL A  27
HIS A  86
 None
 0.85A 6a5yD-3pmcA:
undetectable		 6a5yD-3pmcA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GMD_B_ACTB402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3pmc UNCHARACTERIZED
PROTEIN
PXO2-61/BXB0075/GBAA
_PXO2_0075
(Bacillus
anthracis) 		3 / 3 HIS A 129
SER A 130
LYS A  68
 None
IOD  A 413 (-3.2A)
IOD  A 413 (-2.6A)
 1.44A 6gmdB-3pmcA:
undetectable		 6gmdB-3pmcA:
16.48