SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pmd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_G_BEZG3385_0
(CES1 PROTEIN)		 3pmd CONSERVED DOMAIN
PROTEIN
(Bacillus
anthracis) 		3 / 3 SER A  67
VAL A  49
LEU A  46
 None
None
11A  A 151 ( 4.4A)
 0.71A 1yajG-3pmdA:
undetectable		 1yajG-3pmdA:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_A_1FLA1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 3pmd CONSERVED DOMAIN
PROTEIN
(Bacillus
anthracis) 		4 / 8 LEU A  96
ILE A 113
PRO A 104
LEU A  99
 None
 0.67A 5g48A-3pmdA:
undetectable		 5g48A-3pmdA:
23.08