SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pmi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_E_ZPCE1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3pmi PWWP
DOMAIN-CONTAINING
PROTEIN MUM1
(Homo
sapiens) 		4 / 6 PHE A 466
TYR A 496
VAL A 521
PHE A 509
 None
 1.21A 4a97E-3pmiA:
undetectable		 4a97E-3pmiA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUO_D_08HD501_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT GAMMA-2)		 3pmi PWWP
DOMAIN-CONTAINING
PROTEIN MUM1
(Homo
sapiens) 		4 / 8 TYR A 513
PHE A 509
VAL A 521
SER A 518
 None
 1.04A 6huoC-3pmiA:
undetectable
6huoD-3pmiA:
undetectable		 6huoC-3pmiA:
19.12
6huoD-3pmiA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6I0Y_A_TRPA3001_0
(23S RIBOSOMAL RNA
TRYPTOPHANASE OPERON
LEADER PEPTIDE)		 3pmi PWWP
DOMAIN-CONTAINING
PROTEIN MUM1
(Homo
sapiens) 		3 / 3 TRP A 488
ILE A 486
ASP A 485
 None
 0.66A 6i0y7-3pmiA:
undetectable		 6i0y7-3pmiA:
11.21