SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pmo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4003_1
(SERUM ALBUMIN)		 3pmo UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 6 VAL A  16
GLY A  17
ALA A  85
LEU A  89
 None
 0.74A 1e7bB-3pmoA:
undetectable		 1e7bB-3pmoA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_A_DESA459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3pmo UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  92
LEU A  89
ALA A  87
LEU A  84
VAL A  79
 None
 1.15A 1s9pA-3pmoA:
undetectable		 1s9pA-3pmoA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3pmo UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  92
GLY A  10
TYR A   7
ALA A  13
ALA A  18
 None
 1.11A 2br4A-3pmoA:
undetectable		 2br4A-3pmoA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3pmo UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  92
GLY A  10
TYR A   7
ALA A  13
ALA A  18
 None
 1.10A 2br4C-3pmoA:
undetectable		 2br4C-3pmoA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3pmo UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  92
GLY A  10
TYR A   7
ALA A  13
ALA A  18
 None
 1.11A 2br4D-3pmoA:
undetectable		 2br4D-3pmoA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3pmo UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  92
GLY A  10
TYR A   7
ALA A  13
ALA A  18
 None
 1.08A 2br4E-3pmoA:
undetectable		 2br4E-3pmoA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_F_SAMF301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3pmo UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  92
GLY A  10
TYR A   7
ALA A  13
ALA A  18
 None
 1.02A 2br4F-3pmoA:
undetectable		 2br4F-3pmoA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA502_1
(CYTOCHROME P450 2C8)		 3pmo UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 ILE A 238
ILE A 240
VAL A 244
VAL A 204
ILE A 175
 None
 1.00A 2nnhA-3pmoA:
undetectable		 2nnhA-3pmoA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_2
(CYTOCHROME P450 2C8)		 3pmo UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 8 ILE A 280
ILE A 282
ILE A 246
VAL A 286
 None
 0.68A 2nniA-3pmoA:
undetectable		 2nniA-3pmoA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_A_SAMA500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 3pmo UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 ALA A 171
GLY A 152
GLY A 136
THR A 168
VAL A 150
 None
 1.07A 2okcA-3pmoA:
undetectable		 2okcA-3pmoA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3pmo UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 SER A 177
VAL A 161
ILE A 139
SER A 120
TRP A 156
 None
 1.44A 2vdyA-3pmoA:
undetectable		 2vdyA-3pmoA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_3
(HIV-1 PROTEASE)		 3pmo UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 185
ILE A 201
GLY A 202
GLY A 203
VAL A 204
 None
 0.93A 3cyxB-3pmoA:
undetectable		 3cyxB-3pmoA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_2
(PROTEASE)		 3pmo UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 10 ALA A 119
VAL A 115
ILE A 103
GLY A 122
ILE A 133
 None
 0.92A 3em3B-3pmoA:
undetectable		 3em3B-3pmoA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU6_B_478B401_1
(PROTEASE)		 3pmo UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 10 ALA A 119
VAL A 115
ILE A 103
GLY A 122
ILE A 133
 None
 0.89A 3nu6A-3pmoA:
undetectable		 3nu6A-3pmoA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_C_478C200_2
(HIV-1 PROTEASE)		 3pmo UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 11 ALA A 119
VAL A 115
ILE A 103
GLY A 122
ILE A 133
 None
 0.84A 3oxvD-3pmoA:
undetectable		 3oxvD-3pmoA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_B_017B200_2
(HIV-1 PROTEASE)		 3pmo UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 10 ALA A 119
VAL A 115
ILE A 103
GLY A 122
ILE A 133
 None
 0.89A 3oxwB-3pmoA:
undetectable		 3oxwB-3pmoA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_C_BEZC264_0
(CARNITINYL-COA
DEHYDRATASE)		 3pmo UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 6 ALA A 262
ILE A 264
LEU A 276
ALA A 241
 None
 0.88A 3r9sC-3pmoA:
undetectable		 3r9sC-3pmoA:
24.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_A_TYLA2200_1
(CREB-BINDING PROTEIN)		 3pmo UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 6 VAL A 161
LEU A 163
ILE A 145
VAL A 173
 None
 0.94A 4a9kA-3pmoA:
undetectable		 4a9kA-3pmoA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3pmo UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 SER A 177
VAL A 161
ILE A 139
SER A 120
TRP A 156
 None
 1.47A 4c49B-3pmoA:
undetectable		 4c49B-3pmoA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQB_B_017B101_1
(ASPARTYL PROTEASE)		 3pmo UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 ALA A 119
VAL A 115
ILE A 103
GLY A 122
ILE A 133
 None
 0.88A 4dqbA-3pmoA:
undetectable		 4dqbA-3pmoA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_1
(PROTEASE)		 3pmo UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 11 ALA A 119
VAL A 115
ILE A 103
GLY A 122
ILE A 133
 None
 0.89A 4njtA-3pmoA:
undetectable		 4njtA-3pmoA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_D_017D101_1
(PROTEASE)		 3pmo UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 11 ALA A 119
VAL A 115
ILE A 103
GLY A 122
ILE A 133
 None
 0.93A 4njtC-3pmoA:
undetectable		 4njtC-3pmoA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_A_ML1A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3pmo UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 8 PHE A 287
TYR A 304
GLY A 265
ILE A 246
 None
 0.97A 4qoiA-3pmoA:
undetectable
4qoiB-3pmoA:
undetectable		 4qoiA-3pmoA:
18.02
4qoiB-3pmoA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_1
(HIV-1 PROTEASE)		 3pmo UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 11 ALA A 119
VAL A 115
ILE A 103
GLY A 122
ILE A 133
 None
 0.85A 4rvjA-3pmoA:
undetectable		 4rvjA-3pmoA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_B_ACTB1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 3pmo UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 5 ARG A  58
GLY A  38
ALA A  37
GLY A  60
 None
 0.97A 4u9uB-3pmoA:
undetectable		 4u9uB-3pmoA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_2
(PROTEASE)		 3pmo UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Pseudomonas
aeruginosa) 		6 / 12 GLY A 260
ALA A 241
ILE A 218
GLY A 221
ILE A 246
ILE A 240
 None
 1.33A 5e5jB-3pmoA:
undetectable		 5e5jB-3pmoA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA303_1
(CHITOSANASE)		 3pmo UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 5 HIS A 165
VAL A 150
GLY A 130
ALA A 131
 None
 1.04A 5hwaA-3pmoA:
undetectable		 5hwaA-3pmoA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_B_SAMB201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 3pmo UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 10 ILE A 198
GLY A 187
GLY A 185
LEU A 223
SER A 224
 None
 1.02A 5twjB-3pmoA:
undetectable		 5twjB-3pmoA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIF_B_TPVB201_0
(HIV-1 PROTEASE)		 3pmo UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 ASP A 209
ASP A 208
GLY A 155
VAL A 167
ILE A 206
 None
 1.18A 6difA-3pmoA:
undetectable		 6difA-3pmoA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_1
(CYTOCHROME P450 1A1)		 3pmo UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 7 GLY A 178
ALA A 179
VAL A 173
LEU A 157
 None
 0.82A 6dwnB-3pmoA:
undetectable		 6dwnB-3pmoA:
11.90