SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pna'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LSK_B_ACTB901_0 (PYRANOSE 2-OXIDASE)	3pna	CAMP-DEPENDENT PROTEIN KINASE TYPE I-ALPHA REGULATORY SUBUNIT (Bos taurus)	4 / 6	SER A 197 PHE A 172 PHE A 136 ASN A 133	None	1.27A	3lskB-3pnaA: undetectable	3lskB-3pnaA: 14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LSK_D_ACTD901_0 (PYRANOSE 2-OXIDASE)	3pna	CAMP-DEPENDENT PROTEIN KINASE TYPE I-ALPHA REGULATORY SUBUNIT (Bos taurus)	4 / 6	SER A 197 PHE A 172 PHE A 136 ASN A 133	None	1.32A	3lskD-3pnaA: undetectable	3lskD-3pnaA: 14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N0H_A_TOPA187_1 (DIHYDROFOLATE REDUCTASE)	3pna	CAMP-DEPENDENT PROTEIN KINASE TYPE I-ALPHA REGULATORY SUBUNIT (Bos taurus)	5 / 11	ILE A 163 ALA A 211 PHE A 198 LEU A 221 VAL A 162	CMP A 250 ( 4.3A) CMP A 250 (-3.8A) None None None	1.09A	3n0hA-3pnaA: undetectable	3n0hA-3pnaA: 18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3S3V_A_TOPA187_1 (DIHYDROFOLATE REDUCTASE)	3pna	CAMP-DEPENDENT PROTEIN KINASE TYPE I-ALPHA REGULATORY SUBUNIT (Bos taurus)	5 / 12	ILE A 163 ALA A 211 PHE A 198 LEU A 221 VAL A 162	CMP A 250 ( 4.3A) CMP A 250 (-3.8A) None None None	1.08A	3s3vA-3pnaA: undetectable	3s3vA-3pnaA: 18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TVX_B_PNXB902_1 (CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4A)	3pna	CAMP-DEPENDENT PROTEIN KINASE TYPE I-ALPHA REGULATORY SUBUNIT (Bos taurus)	4 / 7	ILE A 163 PHE A 198 MET A 180 PHE A 156	CMP A 250 ( 4.3A) None None None	1.14A	3tvxB-3pnaA: undetectable	3tvxB-3pnaA: 20.77

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3LSK_B_ACTB901_0","PYRANOSE 2-OXIDASE","3pna","CAMP-DEPENDENT PROTEIN KINASE TYPE I-ALPHA REGULATORY SUBUNIT","Bos taurus",4,"SER A 197;PHE A 172;PHE A 136;ASN A 133","None","1.27A","3lskB-3pnaA:undetectable","3lskB-3pnaA:14.31"],["3LSK_D_ACTD901_0","PYRANOSE 2-OXIDASE","3pna","CAMP-DEPENDENT PROTEIN KINASE TYPE I-ALPHA REGULATORY SUBUNIT","Bos taurus",4,"SER A 197;PHE A 172;PHE A 136;ASN A 133","None","1.32A","3lskD-3pnaA:undetectable","3lskD-3pnaA:14.31"],["3N0H_A_TOPA187_1","DIHYDROFOLATE REDUCTASE","3pna","CAMP-DEPENDENT PROTEIN KINASE TYPE I-ALPHA REGULATORY SUBUNIT","Bos taurus",5,"ILE A 163;ALA A 211;PHE A 198;LEU A 221;VAL A 162","CMP A 250 ( 4.3A);CMP A 250 (-3.8A);None;None;None","1.09A","3n0hA-3pnaA:undetectable","3n0hA-3pnaA:18.32"],["3S3V_A_TOPA187_1","DIHYDROFOLATE REDUCTASE","3pna","CAMP-DEPENDENT PROTEIN KINASE TYPE I-ALPHA REGULATORY SUBUNIT","Bos taurus",5,"ILE A 163;ALA A 211;PHE A 198;LEU A 221;VAL A 162","CMP A 250 ( 4.3A);CMP A 250 (-3.8A);None;None;None","1.08A","3s3vA-3pnaA:undetectable","3s3vA-3pnaA:18.85"],["3TVX_B_PNXB902_1","CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4A","3pna","CAMP-DEPENDENT PROTEIN KINASE TYPE I-ALPHA REGULATORY SUBUNIT","Bos taurus",4,"ILE A 163;PHE A 198;MET A 180;PHE A 156","CMP A 250 ( 4.3A);None;None;None","1.14A","3tvxB-3pnaA:undetectable","3tvxB-3pnaA:20.77"]]