SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pnt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OXT_B_SAMB300_1 (NUCLEOSIDE-2'-O-METH YLTRANSFERASE)	3pnt	IMMUNITY FACTOR FOR SPN (Streptococcus pyogenes)	4 / 5	GLY B 84 HIS B 137 ASP B 152 ASP B 128	None	1.11A	2oxtB-3pntB: undetectable	2oxtB-3pntB: 20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FRQ_B_ERYB195_0 (REPRESSOR PROTEIN MPHR(A))	3pnt	IMMUNITY FACTOR FOR SPN (Streptococcus pyogenes)	5 / 12	THR B 95 LEU B 96 VAL B 21 ILE B 118 SER B 117	None	0.85A	3frqB-3pntB: undetectable	3frqB-3pntB: 24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3R9C_A_ECLA452_1 (CYTOCHROME P450 164A2)	3pnt	IMMUNITY FACTOR FOR SPN (Streptococcus pyogenes)	5 / 12	LEU B 102 ALA B 98 THR B 95 ASN B 97 LEU B 96	None	0.66A	3r9cA-3pntB: undetectable	3r9cA-3pntB: 16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AN2_A_EUIA1382_2 (DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1)	3pnt	IMMUNITY FACTOR FOR SPN (Streptococcus pyogenes)	4 / 4	ASN B 97 SER B 108 LEU B 109 THR B 160	None	1.33A	4an2A-3pntB: undetectable	4an2A-3pntB: 21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LA0_A_198A601_1 (SERUM ALBUMIN)	3pnt	IMMUNITY FACTOR FOR SPN (Streptococcus pyogenes)	5 / 10	LEU B 102 PRO B 110 ALA B 61 GLU B 55 LEU B 113	None	1.20A	4la0A-3pntB: undetectable	4la0A-3pntB: 13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LA0_B_198B601_1 (SERUM ALBUMIN)	3pnt	IMMUNITY FACTOR FOR SPN (Streptococcus pyogenes)	5 / 9	LEU B 102 PRO B 110 ALA B 61 GLU B 55 LEU B 113	None	1.17A	4la0B-3pntB: undetectable	4la0B-3pntB: 13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4W5Q_A_IPHA903_0 (PROTEIN ARGONAUTE-2)	3pnt	IMMUNITY FACTOR FOR SPN (Streptococcus pyogenes)	4 / 5	TYR B 56 PRO B 60 LEU B 102 TYR B 2	None	1.19A	4w5qA-3pntB: undetectable	4w5qA-3pntB: 10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z4C_A_IPHA904_0 (PROTEIN ARGONAUTE-2)	3pnt	IMMUNITY FACTOR FOR SPN (Streptococcus pyogenes)	4 / 6	TYR B 56 PRO B 60 LEU B 102 TYR B 2	None	1.22A	4z4cA-3pntB: undetectable	4z4cA-3pntB: 10.67

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2OXT_B_SAMB300_1","NUCLEOSIDE-2'-O-METHYLTRANSFERASE","3pnt","IMMUNITY FACTOR FOR SPN","Streptococcus pyogenes",4,"GLY B  84;HIS B 137;ASP B 152;ASP B 128","None","1.11A","2oxtB-3pntB:undetectable","2oxtB-3pntB:20.08"],["3FRQ_B_ERYB195_0","REPRESSOR PROTEIN MPHR(A)","3pnt","IMMUNITY FACTOR FOR SPN","Streptococcus pyogenes",5,"THR B  95;LEU B  96;VAL B  21;ILE B 118;SER B 117","None","0.85A","3frqB-3pntB:undetectable","3frqB-3pntB:24.29"],["3R9C_A_ECLA452_1","CYTOCHROME P450 164A2","3pnt","IMMUNITY FACTOR FOR SPN","Streptococcus pyogenes",5,"LEU B 102;ALA B  98;THR B  95;ASN B  97;LEU B  96","None","0.66A","3r9cA-3pntB:undetectable","3r9cA-3pntB:16.97"],["4AN2_A_EUIA1382_2","DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1","3pnt","IMMUNITY FACTOR FOR SPN","Streptococcus pyogenes",4,"ASN B  97;SER B 108;LEU B 109;THR B 160","None","1.33A","4an2A-3pntB:undetectable","4an2A-3pntB:21.19"],["4LA0_A_198A601_1","SERUM ALBUMIN","3pnt","IMMUNITY FACTOR FOR SPN","Streptococcus pyogenes",5,"LEU B 102;PRO B 110;ALA B  61;GLU B  55;LEU B 113","None","1.20A","4la0A-3pntB:undetectable","4la0A-3pntB:13.76"],["4LA0_B_198B601_1","SERUM ALBUMIN","3pnt","IMMUNITY FACTOR FOR SPN","Streptococcus pyogenes",5,"LEU B 102;PRO B 110;ALA B  61;GLU B  55;LEU B 113","None","1.17A","4la0B-3pntB:undetectable","4la0B-3pntB:13.76"],["4W5Q_A_IPHA903_0","PROTEIN ARGONAUTE-2","3pnt","IMMUNITY FACTOR FOR SPN","Streptococcus pyogenes",4,"TYR B  56;PRO B  60;LEU B 102;TYR B   2","None","1.19A","4w5qA-3pntB:undetectable","4w5qA-3pntB:10.67"],["4Z4C_A_IPHA904_0","PROTEIN ARGONAUTE-2","3pnt","IMMUNITY FACTOR FOR SPN","Streptococcus pyogenes",4,"TYR B  56;PRO B  60;LEU B 102;TYR B   2","None","1.22A","4z4cA-3pntB:undetectable","4z4cA-3pntB:10.67"]]