SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pnz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		4 / 8 PHE A  99
HIS A  22
HIS A 215
HIS A  24
 None
ZN  A 333 ( 3.3A)
ZN  A 334 ( 3.4A)
ZN  A 333 ( 3.3A)
 0.98A 1bzmA-3pnzA:
undetectable		 1bzmA-3pnzA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9Y_B_HAEB800_1
(UREASE SUBUNIT BETA)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		4 / 5 HIS A  22
HIS A 187
HIS A 215
ASP A 272
 ZN  A 333 ( 3.3A)
ZN  A 334 ( 3.2A)
ZN  A 334 ( 3.4A)
ZN  A 333 ( 2.8A)
 0.83A 1e9yB-3pnzA:
14.1		 1e9yB-3pnzA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_GLYA1292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		4 / 8 SER A 212
HIS A  22
SER A 236
PHE A 326
 None
ZN  A 333 ( 3.3A)
None
None
 1.31A 1eqbA-3pnzA:
undetectable
1eqbB-3pnzA:
undetectable		 1eqbA-3pnzA:
22.45
1eqbB-3pnzA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_GLYB2292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		4 / 8 PHE A 326
SER A 212
HIS A  22
SER A 236
 None
None
ZN  A 333 ( 3.3A)
None
 1.31A 1eqbA-3pnzA:
undetectable
1eqbB-3pnzA:
undetectable		 1eqbA-3pnzA:
22.45
1eqbB-3pnzA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_GLYC3292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		4 / 8 SER A 212
HIS A  22
SER A 236
PHE A 326
 None
ZN  A 333 ( 3.3A)
None
None
 1.30A 1eqbC-3pnzA:
undetectable
1eqbD-3pnzA:
undetectable		 1eqbC-3pnzA:
22.45
1eqbD-3pnzA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_GLYD4292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		4 / 8 PHE A 326
SER A 212
HIS A  22
SER A 236
 None
None
ZN  A 333 ( 3.3A)
None
 1.30A 1eqbC-3pnzA:
undetectable
1eqbD-3pnzA:
undetectable		 1eqbC-3pnzA:
22.45
1eqbD-3pnzA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA652_1
(AMYLOMALTASE)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		4 / 6 GLY A 239
ASP A 217
GLY A 214
SER A 270
 None
 0.92A 1eswA-3pnzA:
5.3		 1eswA-3pnzA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FWE_C_HAEC989_1
(UREASE)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		5 / 6 HIS A  22
HIS A  24
HIS A 187
HIS A 215
ASP A 272
 ZN  A 333 ( 3.3A)
ZN  A 333 ( 3.3A)
ZN  A 334 ( 3.2A)
ZN  A 334 ( 3.4A)
ZN  A 333 ( 2.8A)
 0.82A 1fweC-3pnzA:
13.8		 1fweC-3pnzA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_A_VIBA502_1
(THIAMIN
PYROPHOSPHOKINASE)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		4 / 8 LEU A 288
SER A  82
ASP A  65
THR A   6
 None
 1.10A 1ig3A-3pnzA:
undetectable
1ig3B-3pnzA:
undetectable		 1ig3A-3pnzA:
21.59
1ig3B-3pnzA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JR1_A_MOAA1332_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		5 / 11 SER A 212
MET A 216
GLY A 191
GLY A 156
GLN A 197
 None
 1.25A 1jr1A-3pnzA:
5.8		 1jr1A-3pnzA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		3 / 3 ASP A 272
HIS A 215
HIS A  22
 ZN  A 333 ( 2.8A)
ZN  A 334 ( 3.4A)
ZN  A 333 ( 3.3A)
 0.63A 1oe1A-3pnzA:
undetectable		 1oe1A-3pnzA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		3 / 3 ASP A 272
HIS A 215
HIS A  22
 ZN  A 333 ( 2.8A)
ZN  A 334 ( 3.4A)
ZN  A 333 ( 3.3A)
 0.63A 1oe3A-3pnzA:
undetectable		 1oe3A-3pnzA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		5 / 11 GLY A 158
GLY A 214
HIS A 187
ALA A 194
ILE A 213
 None
None
ZN  A 334 ( 3.2A)
None
None
 1.14A 1utdL-3pnzA:
undetectable
1utdV-3pnzA:
undetectable		 1utdL-3pnzA:
13.33
1utdV-3pnzA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_A_ACTA294_0
(GLYCINE
N-METHYLTRANSFERASE)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		4 / 5 ILE A 255
LEU A 220
ALA A 250
GLU A 248
 None
 1.16A 1xvaA-3pnzA:
undetectable
1xvaB-3pnzA:
undetectable		 1xvaA-3pnzA:
23.68
1xvaB-3pnzA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVL_B_H4BB920_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		4 / 6 PHE A 328
GLU A 179
ARG A   5
VAL A 153
 None
None
None
KCX  A 154 ( 3.2A)
 1.08A 1zvlA-3pnzA:
undetectable
1zvlB-3pnzA:
undetectable		 1zvlA-3pnzA:
21.14
1zvlB-3pnzA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_A_SHHA2452_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		5 / 11 LEU A 288
ILE A  63
HIS A 215
HIS A  22
GLY A 239
 None
None
ZN  A 334 ( 3.4A)
ZN  A 333 ( 3.3A)
None
 1.09A 1zz1A-3pnzA:
undetectable		 1zz1A-3pnzA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_C_SHHC2652_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		5 / 12 LEU A 288
ILE A  63
HIS A 215
HIS A  22
GLY A 239
 None
None
ZN  A 334 ( 3.4A)
ZN  A 333 ( 3.3A)
None
 1.08A 1zz1C-3pnzA:
undetectable		 1zz1C-3pnzA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOH_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		4 / 5 LEU A  40
ASP A  39
GLY A 285
ALA A 274
 None
None
None
PO4  A 336 ( 4.3A)
 0.88A 2aohA-3pnzA:
undetectable		 2aohA-3pnzA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_F_RBFF204_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		4 / 8 TYR A  31
GLU A 189
PHE A  99
TYR A  71
 None
None
None
PO4  A 335 (-3.8A)
 1.04A 2fl5E-3pnzA:
undetectable
2fl5F-3pnzA:
undetectable		 2fl5E-3pnzA:
20.29
2fl5F-3pnzA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACHB603_0
(ACETYLCHOLINESTERASE)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		4 / 7 TYR A  71
TYR A 279
GLU A  23
GLY A 271
 PO4  A 335 (-3.8A)
None
None
None
 1.23A 2ha4B-3pnzA:
undetectable		 2ha4B-3pnzA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_A_ANWA99_0
(PROTEIN S100-A13)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		4 / 7 VAL A 269
PHE A 318
THR A  19
LYS A 315
 None
 0.98A 2kotA-3pnzA:
undetectable		 2kotA-3pnzA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		4 / 6 ARG A 218
GLY A 191
LYS A 155
THR A 157
 None
None
KCX  A 154 ( 3.5A)
None
 1.01A 2m2oB-3pnzA:
undetectable		 2m2oB-3pnzA:
6.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1500_1
(CYTOCHROME P450 3A4)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		5 / 11 SER A 186
LEU A 195
ILE A 213
ALA A 233
ARG A 175
 None
 1.08A 2v0mA-3pnzA:
undetectable		 2v0mA-3pnzA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1498_1
(CYTOCHROME P450 3A4)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		5 / 12 SER A 186
LEU A 195
ILE A 213
ALA A 233
ARG A 175
 None
 1.10A 2v0mC-3pnzA:
undetectable		 2v0mC-3pnzA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1498_1
(CYTOCHROME P450 3A4)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		5 / 11 SER A 186
LEU A 195
ILE A 213
ALA A 233
ARG A 175
 None
 1.14A 2v0mD-3pnzA:
undetectable		 2v0mD-3pnzA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		3 / 3 ASP A 272
HIS A 215
HIS A  22
 ZN  A 333 ( 2.8A)
ZN  A 334 ( 3.4A)
ZN  A 333 ( 3.3A)
 0.65A 2xxgA-3pnzA:
undetectable		 2xxgA-3pnzA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1339_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		3 / 3 ASP A 272
HIS A 215
HIS A  22
 ZN  A 333 ( 2.8A)
ZN  A 334 ( 3.4A)
ZN  A 333 ( 3.3A)
 0.65A 2xxgC-3pnzA:
undetectable		 2xxgC-3pnzA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_B_TP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		5 / 12 PHE A 326
VAL A  90
PHE A  55
LEU A 288
HIS A  22
 None
None
None
None
ZN  A 333 ( 3.3A)
 1.31A 3apvB-3pnzA:
undetectable		 3apvB-3pnzA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOD_A_HQEA1173_1
(FMN-BINDING PROTEIN)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		4 / 7 TYR A  71
HIS A 187
ARG A 218
HIS A  24
 PO4  A 335 (-3.8A)
ZN  A 334 ( 3.2A)
None
ZN  A 333 ( 3.3A)
 1.28A 3zodA-3pnzA:
undetectable		 3zodA-3pnzA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		5 / 12 SER A  48
VAL A  52
GLN A 152
ILE A  89
HIS A  22
 None
None
None
None
ZN  A 333 ( 3.3A)
 1.46A 4c49D-3pnzA:
undetectable		 4c49D-3pnzA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_D_FOLD703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		5 / 10 VAL A 135
ALA A 150
PHE A 328
VAL A 136
THR A  92
 None
None
None
None
KCX  A 154 ( 4.4A)
 1.48A 4eilD-3pnzA:
undetectable		 4eilD-3pnzA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H9M_A_HAEA929_1
(UREASE)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		4 / 5 HIS A  22
HIS A 187
HIS A 215
ASP A 272
 ZN  A 333 ( 3.3A)
ZN  A 334 ( 3.2A)
ZN  A 334 ( 3.4A)
ZN  A 333 ( 2.8A)
 0.81A 4h9mA-3pnzA:
5.0		 4h9mA-3pnzA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLB_A_TRPA901_0
(PROTEIN ARGONAUTE-2)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		3 / 3 VAL A  90
ALA A 150
PHE A   7
 None
 0.91A 4olbA-3pnzA:
undetectable		 4olbA-3pnzA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBP_C_HAEC800_1
(PROTEIN (UREASE
(CHAIN C)))		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		5 / 6 HIS A  22
HIS A  24
HIS A 187
HIS A 215
ASP A 272
 ZN  A 333 ( 3.3A)
ZN  A 333 ( 3.3A)
ZN  A 334 ( 3.2A)
ZN  A 334 ( 3.4A)
ZN  A 333 ( 2.8A)
 0.69A 4ubpC-3pnzA:
4.2		 4ubpC-3pnzA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA602_1
(SERUM ALBUMIN)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		4 / 8 ASP A  51
VAL A  26
LYS A  45
GLU A  46
 None
 0.78A 4zbqA-3pnzA:
undetectable		 4zbqA-3pnzA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_E_SAME301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		5 / 12 ALA A 190
GLY A 191
GLY A 214
ASP A 217
LEU A 220
 None
 1.18A 5c0oE-3pnzA:
undetectable		 5c0oE-3pnzA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_A_BEZA1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		4 / 6 GLY A  91
THR A  92
VAL A  64
HIS A  24
 None
KCX  A 154 ( 4.4A)
None
ZN  A 333 ( 3.3A)
 1.00A 5ewuA-3pnzA:
undetectable		 5ewuA-3pnzA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_B_BEZB1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		4 / 6 GLY A  91
THR A  92
VAL A  64
HIS A  24
 None
KCX  A 154 ( 4.4A)
None
ZN  A 333 ( 3.3A)
 0.97A 5ewuB-3pnzA:
undetectable		 5ewuB-3pnzA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		4 / 7 ARG A   5
VAL A 153
PHE A 328
GLU A 179
 None
KCX  A 154 ( 3.2A)
None
None
 1.04A 5g0pA-3pnzA:
undetectable
5g0pB-3pnzA:
undetectable		 5g0pA-3pnzA:
21.49
5g0pB-3pnzA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		4 / 7 VAL A 136
VAL A 153
PHE A 328
GLU A 179
 None
KCX  A 154 ( 3.2A)
None
None
 1.07A 5g0pA-3pnzA:
undetectable
5g0pB-3pnzA:
undetectable		 5g0pA-3pnzA:
21.49
5g0pB-3pnzA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_C_MZMC301_1
(CARBONIC ANHYDRASE 4)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		5 / 9 GLN A 152
HIS A 185
HIS A  22
VAL A  64
LEU A 268
 None
None
ZN  A 333 ( 3.3A)
None
None
 1.39A 5ku6C-3pnzA:
undetectable		 5ku6C-3pnzA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		5 / 12 VAL A  64
ASP A  65
GLU A  23
LEU A 211
SER A 270
 None
 1.13A 5nd7B-3pnzA:
undetectable		 5nd7B-3pnzA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_A_CCSA14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		4 / 6 ASN A  96
LEU A 100
TRP A 101
GLY A 103
 PO4  A 335 ( 2.8A)
None
None
None
 0.95A 5o4yA-3pnzA:
undetectable		 5o4yA-3pnzA:
4.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		4 / 7 PHE A 328
GLU A 179
ARG A   5
VAL A 153
 None
None
None
KCX  A 154 ( 3.2A)
 1.01A 5vv5A-3pnzA:
0.0
5vv5B-3pnzA:
0.0		 5vv5A-3pnzA:
19.81
5vv5B-3pnzA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_B_ADNB503_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		4 / 5 LEU A 256
VAL A 259
GLU A 264
LEU A 313
 None
 1.00A 5xooB-3pnzA:
undetectable		 5xooB-3pnzA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DCH_A_ACTA401_0
(SCOE PROTEIN)		 3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN
(Listeria
monocytogenes) 		4 / 5 THR A  67
HIS A  22
ASP A 272
HIS A 215
 None
ZN  A 333 ( 3.3A)
ZN  A 333 ( 2.8A)
ZN  A 334 ( 3.4A)
 1.07A 6dchA-3pnzA:
undetectable		 6dchA-3pnzA:
22.40