SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3po0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2GLU_B_SAMB302_0 (YCGJ)	3po0	SMALL ARCHAEAL MODIFIER PROTEIN 1 (Haloferax volcanii)	5 / 12	GLY A 69 GLY A 29 ALA A 71 THR A 72 ALA A 67	None	1.05A	2gluB-3po0A: undetectable	2gluB-3po0A: 17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3E22_D_LOCD700_2 (TUBULIN BETA-2B CHAIN)	3po0	SMALL ARCHAEAL MODIFIER PROTEIN 1 (Haloferax volcanii)	6 / 11	LEU A 60 LEU A 80 ALA A 79 LEU A 78 MET A 1 ALA A 31	None	1.49A	3e22D-3po0A: undetectable	3e22D-3po0A: 11.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JW3_B_TOPB208_1 (DIHYDROFOLATE REDUCTASE)	3po0	SMALL ARCHAEAL MODIFIER PROTEIN 1 (Haloferax volcanii)	5 / 9	ALA A 13 LEU A 5 VAL A 36 ILE A 57 LEU A 53	None	1.32A	3jw3B-3po0A: undetectable	3jw3B-3po0A: 18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WG0_H_CHDH103_0 (NUCLEAR RECEPTOR COACTIVATOR 2)	3po0	SMALL ARCHAEAL MODIFIER PROTEIN 1 (Haloferax volcanii)	5 / 11	LEU A 9 LEU A 5 GLU A 43 LEU A 42 LEU A 35	None None MG A 92 (-2.2A) None None	1.16A	4wg0H-3po0A: undetectable 4wg0I-3po0A: undetectable 4wg0J-3po0A: undetectable	4wg0H-3po0A: 25.00 4wg0I-3po0A: 25.00 4wg0J-3po0A: 25.00

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2GLU_B_SAMB302_0","YCGJ","3po0","SMALL ARCHAEAL MODIFIER PROTEIN 1","Haloferax volcanii",5,"GLY A  69;GLY A  29;ALA A  71;THR A  72;ALA A  67","None","1.05A","2gluB-3po0A:undetectable","2gluB-3po0A:17.39"],["3E22_D_LOCD700_2","TUBULIN BETA-2B CHAIN","3po0","SMALL ARCHAEAL MODIFIER PROTEIN 1","Haloferax volcanii",6,"LEU A  60;LEU A  80;ALA A  79;LEU A  78;MET A   1;ALA A  31","None","1.49A","3e22D-3po0A:undetectable","3e22D-3po0A:11.72"],["3JW3_B_TOPB208_1","DIHYDROFOLATE REDUCTASE","3po0","SMALL ARCHAEAL MODIFIER PROTEIN 1","Haloferax volcanii",5,"ALA A  13;LEU A   5;VAL A  36;ILE A  57;LEU A  53","None","1.32A","3jw3B-3po0A:undetectable","3jw3B-3po0A:18.59"],["4WG0_H_CHDH103_0","NUCLEAR RECEPTOR COACTIVATOR 2","3po0","SMALL ARCHAEAL MODIFIER PROTEIN 1","Haloferax volcanii",5,"LEU A   9;LEU A   5;GLU A  43;LEU A  42;LEU A  35","None;None; MG A  92 (-2.2A);None;None","1.16A","4wg0H-3po0A:undetectable;4wg0I-3po0A:undetectable;4wg0J-3po0A:undetectable","4wg0H-3po0A:25.00;4wg0I-3po0A:25.00;4wg0J-3po0A:25.00"]]