SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3poa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 3poa PUTATIVE
UNCHARACTERIZED
PROTEIN TB39.8
(Mycobacterium
tuberculosis) 		4 / 7 LEU A  10
GLN A   9
PHE A  35
LEU A  37
 None
 1.01A 3ag2C-3poaA:
undetectable		 3ag2C-3poaA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3poa PUTATIVE
UNCHARACTERIZED
PROTEIN TB39.8
(Mycobacterium
tuberculosis) 		4 / 7 LEU A  10
GLN A   9
PHE A  35
LEU A  37
 None
 1.00A 3ag2P-3poaA:
undetectable
3ag2W-3poaA:
undetectable		 3ag2P-3poaA:
17.99
3ag2W-3poaA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_2
(PROTEASE)		 3poa PUTATIVE
UNCHARACTERIZED
PROTEIN TB39.8
(Mycobacterium
tuberculosis) 		5 / 11 ARG A  16
LEU A  10
ASP A  83
ILE A  85
ILE A  92
 None
 1.19A 3s53B-3poaA:
undetectable		 3s53B-3poaA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRJ_A_RAPA201_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4
SERINE/THREONINE-PRO
TEIN KINASE MTOR)		 3poa PUTATIVE
UNCHARACTERIZED
PROTEIN TB39.8
(Mycobacterium
tuberculosis) 		4 / 8 LEU A  47
SER A  63
THR A  40
ASP A  39
 None
 1.10A 4drjB-3poaA:
undetectable		 4drjB-3poaA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBS_A_DIFA503_1
(PENTALENIC ACID
SYNTHASE)		 3poa PUTATIVE
UNCHARACTERIZED
PROTEIN TB39.8
(Mycobacterium
tuberculosis) 		4 / 7 LEU A  87
ALA A  33
LEU A   8
ILE A  26
 None
 0.85A 4ubsA-3poaA:
undetectable		 4ubsA-3poaA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3poa PUTATIVE
UNCHARACTERIZED
PROTEIN TB39.8
(Mycobacterium
tuberculosis) 		4 / 6 ILE A  85
LEU A  87
ARG A  95
THR A  17
 None
 1.01A 5b1aN-3poaA:
undetectable
5b1aW-3poaA:
undetectable		 5b1aN-3poaA:
10.83
5b1aW-3poaA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3poa PUTATIVE
UNCHARACTERIZED
PROTEIN TB39.8
(Mycobacterium
tuberculosis) 		4 / 7 LEU A  10
GLN A   9
PHE A  35
LEU A  37
 None
 0.99A 5b3sC-3poaA:
undetectable
5b3sJ-3poaA:
undetectable		 5b3sC-3poaA:
17.99
5b3sJ-3poaA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 3poa PUTATIVE
UNCHARACTERIZED
PROTEIN TB39.8
(Mycobacterium
tuberculosis) 		4 / 7 LEU A  10
GLN A   9
PHE A  35
LEU A  37
 None
 1.00A 5b3sP-3poaA:
undetectable		 5b3sP-3poaA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_D_ILED602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3poa PUTATIVE
UNCHARACTERIZED
PROTEIN TB39.8
(Mycobacterium
tuberculosis) 		4 / 6 ILE A  85
ALA A  72
THR A  68
VAL A  74
 None
 0.77A 5eclD-3poaA:
undetectable		 5eclD-3poaA:
11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3poa PUTATIVE
UNCHARACTERIZED
PROTEIN TB39.8
(Mycobacterium
tuberculosis) 		4 / 6 ILE A  85
LEU A  87
ARG A  95
THR A  17
 None
 1.00A 6nmfN-3poaA:
undetectable
6nmfW-3poaA:
undetectable		 6nmfN-3poaA:
10.83
6nmfW-3poaA:
14.42