SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3poh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_1
(SUN PROTEIN)		 3poh ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE F1
(Bacteroides
thetaiotaomicron) 		3 / 3 PRO A 469
ASP A 466
ASP A 475
 None
 0.66A 1sqfA-3pohA:
undetectable		 1sqfA-3pohA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3poh ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE F1
(Bacteroides
thetaiotaomicron) 		5 / 12 ALA A 369
TYR A 359
VAL A 352
GLY A 388
ILE A 387
 None
 1.24A 2dcfA-3pohA:
undetectable		 2dcfA-3pohA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 3poh ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE F1
(Bacteroides
thetaiotaomicron) 		3 / 3 ASP A 312
ASN A 310
THR A 341
 None
 0.81A 2q63B-3pohA:
undetectable		 2q63B-3pohA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3poh ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE F1
(Bacteroides
thetaiotaomicron) 		4 / 6 PRO A 346
ILE A 174
ASN A 100
LEU A  96
 None
IMD  A 500 ( 4.1A)
None
None
 1.15A 2wekB-3pohA:
undetectable		 2wekB-3pohA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLK_B_SPMB1302_1
(ATP-SENSITIVE INWARD
RECTIFIER POTASSIUM
CHANNEL 10)		 3poh ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE F1
(Bacteroides
thetaiotaomicron) 		4 / 4 ALA A 378
TYR A 359
ALA A 383
TYR A 385
 None
 1.26A 2wlkA-3pohA:
undetectable
2wlkB-3pohA:
undetectable		 2wlkA-3pohA:
20.04
2wlkB-3pohA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A65_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3poh ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE F1
(Bacteroides
thetaiotaomicron) 		5 / 12 ALA A 369
TYR A 359
VAL A 352
GLY A 388
ILE A 387
 None
 1.17A 3a65A-3pohA:
undetectable		 3a65A-3pohA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3poh ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE F1
(Bacteroides
thetaiotaomicron) 		4 / 8 LEU A  77
ASN A  46
ASP A 162
ILE A 163
 None
 0.94A 4k0bA-3pohA:
undetectable		 4k0bA-3pohA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3poh ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE F1
(Bacteroides
thetaiotaomicron) 		4 / 8 LEU A  77
ASN A  46
ASP A 162
ILE A 163
 None
 0.93A 4l7iA-3pohA:
undetectable		 4l7iA-3pohA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA306_1
(CHITOSANASE)		 3poh ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE F1
(Bacteroides
thetaiotaomicron) 		3 / 3 SER A 316
ASP A 278
GLN A 243
 None
 0.81A 4oltA-3pohA:
undetectable
4oltB-3pohA:
undetectable		 4oltA-3pohA:
21.09
4oltB-3pohA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DB5_A_CYSA503_0
(CYSTEINE DESULFURASE)		 3poh ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE F1
(Bacteroides
thetaiotaomicron) 		4 / 8 ASN A 305
LYS A 348
ARG A 263
THR A 149
 None
 1.20A 5db5A-3pohA:
undetectable
5db5B-3pohA:
undetectable		 5db5A-3pohA:
21.37
5db5B-3pohA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KI6_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 3poh ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE F1
(Bacteroides
thetaiotaomicron) 		4 / 5 LEU A 258
LYS A 464
LEU A 251
TYR A 250
 None
 1.45A 5ki6A-3pohA:
undetectable		 5ki6A-3pohA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N9X_A_THRA601_0
(ADENYLATION DOMAIN)		 3poh ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE F1
(Bacteroides
thetaiotaomicron) 		4 / 7 ASP A 222
GLY A 191
GLY A 189
HIS A  65
 None
 0.99A 5n9xA-3pohA:
undetectable		 5n9xA-3pohA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GSD_A_STRA401_0
(PROGESTERONE
5-BETA-REDUCTASE)		 3poh ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE F1
(Bacteroides
thetaiotaomicron) 		5 / 12 VAL A 225
MET A 358
SER A 399
VAL A 376
ILE A 375
 None
 1.26A 6gsdA-3pohA:
undetectable		 6gsdA-3pohA:
11.51