SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pop'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B02_A_C2FA281_0
(PROTEIN (THYMIDYLATE
SYNTHASE))		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		5 / 11 ALA A 483
LEU A 153
ASP A 176
LEU A 180
GLY A 181
 None
 1.08A 1b02A-3popA:
undetectable		 1b02A-3popA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_1
(VITAMIN D NUCLEAR
RECEPTOR)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		5 / 12 LEU A 112
LEU A 216
SER A 205
VAL A 108
LEU A 133
 None
None
None
None
FAD  A 499 (-4.0A)
 1.33A 1db1A-3popA:
undetectable		 1db1A-3popA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_2
(BETA-LACTAMASE)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		4 / 5 PRO A 231
LEU A 278
THR A 242
ARG A 246
 None
 0.90A 1i2wA-3popA:
undetectable		 1i2wA-3popA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_A_T44A128_1
(TRANSTHYRETIN)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		5 / 10 LEU A 112
ALA A 219
LEU A 216
LEU A 142
LEU A 146
 None
 1.17A 1ie4A-3popA:
0.8
1ie4C-3popA:
undetectable		 1ie4A-3popA:
13.03
1ie4C-3popA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWJ_A_CAMA418_0
(CYTOCHROME P450-CAM)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		5 / 9 THR A 489
LEU A  80
VAL A  58
VAL A 167
VAL A 161
 None
 1.46A 1iwjA-3popA:
0.0		 1iwjA-3popA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		4 / 5 TYR A 474
TYR A 470
ILE A 446
GLY A 497
 None
 1.23A 1kifA-3popA:
undetectable		 1kifA-3popA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		4 / 5 TYR A 474
TYR A 470
ILE A 446
GLY A 497
 None
 1.22A 1kifB-3popA:
undetectable		 1kifB-3popA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		4 / 5 TYR A 474
TYR A 470
ILE A 446
GLY A 497
 None
 1.23A 1kifC-3popA:
undetectable		 1kifC-3popA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		4 / 5 TYR A 474
TYR A 470
ILE A 446
GLY A 497
 None
 1.23A 1kifD-3popA:
undetectable		 1kifD-3popA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		4 / 5 TYR A 474
TYR A 470
ILE A 446
GLY A 497
 None
 1.22A 1kifE-3popA:
undetectable		 1kifE-3popA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		4 / 5 TYR A 474
TYR A 470
ILE A 446
GLY A 497
 None
 1.22A 1kifF-3popA:
undetectable		 1kifF-3popA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		4 / 5 TYR A 474
TYR A 470
ILE A 446
GLY A 497
 None
 1.22A 1kifG-3popA:
undetectable		 1kifG-3popA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		4 / 5 TYR A 474
TYR A 470
ILE A 446
GLY A 497
 None
 1.22A 1kifH-3popA:
undetectable		 1kifH-3popA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		5 / 10 THR A 489
LEU A  80
VAL A  58
VAL A 167
VAL A 161
 None
 1.48A 1o76A-3popA:
undetectable		 1o76A-3popA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZZ_A_ACTA421_0
(ACLACINOMYCIN-10-HYD
ROXYLASE)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		5 / 8 TYR A 201
GLY A 136
GLY A 132
GLY A 131
LEU A 133
 None
None
FAD  A 499 (-3.2A)
FAD  A 499 (-3.5A)
FAD  A 499 (-4.0A)
 0.98A 1qzzA-3popA:
undetectable		 1qzzA-3popA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		5 / 8 THR A 489
LEU A  80
VAL A  58
VAL A 167
VAL A 161
 None
 1.50A 1t86A-3popA:
undetectable		 1t86A-3popA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		5 / 9 THR A 489
LEU A  80
VAL A  58
VAL A 167
VAL A 161
 None
 1.48A 1t86B-3popA:
undetectable		 1t86B-3popA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_B_DESB128_1
(TRANSTHYRETIN)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		5 / 11 LEU A 142
LEU A 146
LEU A 112
ALA A 219
LEU A 216
 None
 1.18A 1tz8A-3popA:
undetectable
1tz8B-3popA:
undetectable		 1tz8A-3popA:
15.02
1tz8B-3popA:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		4 / 5 TYR A 474
TYR A 470
ILE A 446
GLY A 497
 None
 1.25A 1ve9A-3popA:
undetectable		 1ve9A-3popA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		4 / 5 TYR A 474
TYR A 470
ILE A 446
GLY A 497
 None
 1.26A 2du8G-3popA:
undetectable		 2du8G-3popA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H21_B_SAMB802_0
(RIBULOSE-1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		5 / 11 GLU A 252
SER A 377
ARG A 144
HIS A 346
PHE A 248
 None
 1.19A 2h21B-3popA:
undetectable		 2h21B-3popA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H21_C_SAMC803_0
(RIBULOSE-1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		5 / 11 GLU A 252
SER A 377
ARG A 144
HIS A 346
PHE A 248
 None
 1.38A 2h21C-3popA:
undetectable		 2h21C-3popA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_0
(ESTROGEN RECEPTOR)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		5 / 12 LEU A 153
LEU A 146
LEU A 216
LEU A 120
GLY A  96
 None
 0.96A 2ouzA-3popA:
undetectable		 2ouzA-3popA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_1
(PROGESTERONE
RECEPTOR)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		5 / 12 LEU A 153
LEU A 148
GLY A 138
PHE A 184
VAL A 128
 None
None
FAD  A 499 (-3.5A)
None
FAD  A 499 (-4.1A)
 1.23A 2w8yA-3popA:
undetectable		 2w8yA-3popA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CSJ_B_CBLB211_0
(GLUTATHIONE
S-TRANSFERASE P)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		5 / 9 VAL A 150
GLY A 189
ILE A 446
TYR A 445
GLY A 138
 None
None
None
FAD  A 499 (-4.4A)
FAD  A 499 (-3.5A)
 1.25A 3csjB-3popA:
undetectable		 3csjB-3popA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		5 / 12 ILE A 446
GLY A 191
GLY A 190
ALA A 186
ILE A 496
 None
 0.97A 3jayA-3popA:
undetectable		 3jayA-3popA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWQ_B_VIAB901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
CATALYTIC DOMAIN,
CONE CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
SUBUNIT ALPHA
CHIMERA)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		5 / 11 LEU A 355
ALA A 344
VAL A 373
LEU A 420
PHE A 427
 None
 1.44A 3jwqB-3popA:
undetectable
3jwqC-3popA:
undetectable		 3jwqB-3popA:
20.85
3jwqC-3popA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VNS_A_DVAA602_0
(NRPS ADENYLATION
PROTEIN CYTC1)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		4 / 7 ASP A 485
PHE A 195
GLY A 193
THR A 489
 None
None
FAD  A 499 (-3.7A)
None
 0.98A 3vnsA-3popA:
undetectable		 3vnsA-3popA:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_C_SAMC1263_0
(NON-STRUCTURAL
PROTEIN 5)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		5 / 12 GLY A 129
GLY A 137
GLY A 131
HIS A 152
VAL A 392
 FAD  A 499 (-3.6A)
None
FAD  A 499 (-3.5A)
None
None
 0.93A 4ctjC-3popA:
undetectable		 4ctjC-3popA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		5 / 12 ARG A 338
GLY A  72
VAL A  30
GLU A  31
VAL A  71
 None
None
None
None
FAD  A 499 ( 4.5A)
 1.20A 4danA-3popA:
undetectable
4danB-3popA:
undetectable		 4danA-3popA:
19.04
4danB-3popA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRJ_A_RAPA201_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4
SERINE/THREONINE-PRO
TEIN KINASE MTOR)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		4 / 8 LEU A 278
THR A 238
ASP A 236
PHE A 230
 None
 1.04A 4drjB-3popA:
undetectable		 4drjB-3popA:
10.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H2G_A_ADNA603_1
(5'-NUCLEOTIDASE)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		5 / 9 ASN A 194
GLY A 191
GLY A 192
PHE A  70
GLY A 190
 None
None
FAD  A 499 (-3.4A)
None
None
 1.23A 4h2gA-3popA:
undetectable		 4h2gA-3popA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_F_TR6F101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		4 / 5 GLY A 418
ARG A 421
GLY A 422
GLU A 425
 None
 1.22A 4z2eB-3popA:
undetectable
4z2eC-3popA:
undetectable		 4z2eB-3popA:
22.18
4z2eC-3popA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HQA_A_ACRA705_2
(ALPHA-GLUCOSIDASE)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		4 / 8 TRP A 419
PHE A 427
HIS A 363
THR A 267
 None
 1.04A 5hqaA-3popA:
undetectable		 5hqaA-3popA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_C_FUAC1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		3 / 3 VAL A  99
HIS A 152
VAL A 149
 None
 0.63A 5jmnC-3popA:
2.9		 5jmnC-3popA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_1
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		5 / 12 GLY A 190
GLY A 102
PHE A 203
GLY A 138
GLY A 137
 None
None
None
FAD  A 499 (-3.5A)
None
 0.84A 5koxA-3popA:
undetectable		 5koxA-3popA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QSA615_1
(SERUM ALBUMIN)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		4 / 8 LEU A 355
VAL A 243
LEU A 362
ILE A 235
 None
 0.74A 5v0vA-3popA:
undetectable		 5v0vA-3popA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_A_SAMA301_0
(METHYLTRANSFERASE)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		5 / 12 GLY A 129
GLY A 137
GLY A 131
HIS A 152
VAL A 392
 FAD  A 499 (-3.6A)
None
FAD  A 499 (-3.5A)
None
None
 0.94A 5vimA-3popA:
undetectable		 5vimA-3popA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WQP_A_NCAA302_0
(PROBABLE
DEHYDROGENASE)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		4 / 8 GLN A 226
MET A 326
TYR A 325
MET A 317
 None
 1.25A 5wqpA-3popA:
undetectable		 5wqpA-3popA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_B_P2EB1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		4 / 5 PRO A 121
VAL A 149
GLY A  89
VAL A 108
 None
 0.99A 6ak3B-3popA:
undetectable		 6ak3B-3popA:
10.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_1
(CYTOCHROME P450 1A1)		 3pop GILR OXIDASE
(Streptomyces
griseoflavus) 		3 / 3 SER A 274
SER A 275
ALA A 406
 None
 0.61A 6dwnC-3popA:
undetectable		 6dwnC-3popA:
9.73