SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pow'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_A_MIYA2001_1
(TETX2 PROTEIN)		 3pow CALRETICULIN
(Homo
sapiens) 		5 / 11 GLN A 320
HIS A  99
GLY A 107
PHE A  49
GLY A  65
 None
None
None
None
CA  A 900 ( 4.9A)
 1.49A 3v3nA-3powA:
undetectable		 3v3nA-3powA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_D_MIYD2001_1
(TETX2 PROTEIN)		 3pow CALRETICULIN
(Homo
sapiens) 		5 / 11 GLN A 320
HIS A  99
GLY A 107
PHE A  49
GLY A  65
 None
None
None
None
CA  A 900 ( 4.9A)
 1.49A 3v3nD-3powA:
undetectable		 3v3nD-3powA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_STRA301_2
(ANCESTRAL STEROID
RECEPTOR 2)		 3pow CALRETICULIN
(Homo
sapiens) 		4 / 8 ALA A  76
MET A 122
VAL A  93
PHE A  95
 None
 1.04A 4ltwA-3powA:
undetectable		 4ltwA-3powA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8V_B_MIYB1103_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3pow CALRETICULIN
(Homo
sapiens) 		5 / 12 GLN A 101
GLY A 106
ASP A 165
PHE A 327
VAL A  97
 None
 0.94A 4u8vB-3powA:
undetectable		 4u8vB-3powA:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_B_0HKB1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 3pow CALRETICULIN
(Homo
sapiens) 		3 / 3 ASP A 309
ASN A 115
PHE A 113
 None
 0.80A 5dsgB-3powA:
undetectable		 5dsgB-3powA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZNI_A_YMZA302_0
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3pow CALRETICULIN
(Homo
sapiens) 		5 / 9 VAL A 184
TYR A 172
VAL A 110
ASP A 135
GLY A 107
 None
 1.24A 5zniA-3powA:
undetectable		 5zniA-3powA:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_A_HISA402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 3pow CALRETICULIN
(Homo
sapiens) 		5 / 10 GLY A  65
LEU A  66
THR A 325
VAL A  97
LEU A 316
 CA  A 900 ( 4.9A)
None
None
None
None
 1.09A 6czmA-3powA:
undetectable
6czmC-3powA:
undetectable		 6czmA-3powA:
21.66
6czmC-3powA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_B_HISB402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 3pow CALRETICULIN
(Homo
sapiens) 		5 / 9 LEU A 316
GLY A  65
LEU A  66
THR A 325
VAL A  97
 None
CA  A 900 ( 4.9A)
None
None
None
 1.06A 6czmA-3powA:
undetectable
6czmB-3powA:
undetectable		 6czmA-3powA:
21.66
6czmB-3powA:
21.66