SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3poy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZM_A_BZMA600_0
(ODORANT-BINDING
PROTEIN)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		4 / 8 VAL A 453
ASN A 334
GLY A 459
LEU A 461
 None
 0.77A 1dzmA-3poyA:
undetectable		 1dzmA-3poyA:
9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4001_1
(SERUM ALBUMIN)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 9 LEU A 638
ILE A 514
VAL A 691
GLY A 690
ALA A 683
 None
 1.27A 1e7aA-3poyA:
undetectable		 1e7aA-3poyA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		6 / 12 ILE A 965
GLN A 955
PHE A 956
LEU A1076
ALA A1077
HIS A 986
 None
 1.18A 1fbyA-3poyA:
undetectable		 1fbyA-3poyA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_B_9CRB1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		6 / 12 ILE A 965
GLN A 955
PHE A 956
LEU A1076
ALA A1077
HIS A 986
 None
 1.18A 1fbyB-3poyA:
undetectable		 1fbyB-3poyA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_B_VIBB501_1
(THIAMIN
PYROPHOSPHOKINASE)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		4 / 7 GLN A 675
ASP A 673
SER A 454
ASN A 455
 None
 1.23A 1ig3A-3poyA:
undetectable
1ig3B-3poyA:
undetectable		 1ig3A-3poyA:
13.88
1ig3B-3poyA:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ILQ_C_ACAC7_1
(INTERLEUKIN-8
PRECURSOR
INTERLEUKIN-8
RECEPTOR A)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		4 / 6 HIS A 544
ASP A 633
ASP A 631
PRO A 547
 None
 1.48A 1ilqA-3poyA:
undetectable
1ilqC-3poyA:
undetectable		 1ilqA-3poyA:
5.68
1ilqC-3poyA:
1.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_2
(ADENOSINE KINASE)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		4 / 4 SER A 543
LEU A 648
TYR A 637
GLY A 545
 None
 1.26A 1liiA-3poyA:
undetectable		 1liiA-3poyA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_B_SAMB2401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 12 GLY A 365
GLY A 363
ILE A 360
LEU A 336
PRO A 452
 None
 1.12A 1p91B-3poyA:
undetectable		 1p91B-3poyA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		4 / 8 THR A 760
VAL A 803
VAL A 765
VAL A 837
 None
 0.94A 1t86A-3poyA:
undetectable		 1t86A-3poyA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		4 / 7 PHE A 897
THR A 781
LEU A 865
VAL A 837
 None
 1.01A 1yrdA-3poyA:
undetectable		 1yrdA-3poyA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2002_1
(SERUM ALBUMIN)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 11 LEU A 358
ILE A 360
LEU A 362
TYR A 346
GLY A 365
 None
 1.19A 2bxmA-3poyA:
undetectable		 2bxmA-3poyA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_A_LPRA705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 12 HIS A 555
ALA A 553
GLN A 557
GLU A 761
HIS A 862
 None
 1.28A 2c6nA-3poyA:
undetectable		 2c6nA-3poyA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		3 / 3 THR A1058
PRO A1063
TYR A 967
 None
 0.77A 2dxrA-3poyA:
undetectable		 2dxrA-3poyA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_A_AG2A671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		4 / 7 LEU A 630
LEU A 575
ILE A 584
MET A 579
 None
 1.05A 2qqdA-3poyA:
undetectable
2qqdE-3poyA:
undetectable		 2qqdA-3poyA:
5.33
2qqdE-3poyA:
6.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		4 / 7 PHE A 897
THR A 781
LEU A 865
VAL A 837
 None
 1.05A 3fwiA-3poyA:
undetectable		 3fwiA-3poyA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_C_VIBC223_1
(THIAMINE
PYROPHOSPHOKINASE)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		4 / 8 TYR A1050
LEU A 964
LEU A1062
SER A 969
 None
 1.03A 3lm8A-3poyA:
undetectable
3lm8C-3poyA:
undetectable		 3lm8A-3poyA:
13.76
3lm8C-3poyA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDI_A_SAMA601_0
(METHYLTRANSFERASE)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 12 PHE A 531
TYR A 599
ILE A 612
PHE A 603
ILE A 566
 None
 1.29A 3ndiA-3poyA:
undetectable		 3ndiA-3poyA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_A_T1CA392_1
(TETX2 PROTEIN)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 11 GLN A1124
PHE A1128
GLY A1127
GLY A1119
ASN A1143
 None
 1.20A 4a6nA-3poyA:
undetectable		 4a6nA-3poyA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 12 SER A 528
VAL A 601
THR A 533
ILE A 540
PHE A 531
 None
 1.28A 4c49A-3poyA:
undetectable		 4c49A-3poyA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 12 SER A 528
VAL A 601
THR A 533
ILE A 540
PHE A 531
 None
 1.43A 4c49B-3poyA:
undetectable		 4c49B-3poyA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV7_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		3 / 3 LYS A 553
PRO A 556
LYS A 560
 None
 1.22A 4dv7L-3poyA:
undetectable		 4dv7L-3poyA:
8.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FAK_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 10 LEU A 905
ILE A 903
GLY A 909
SER A 894
THR A 740
 None
 0.87A 4fakA-3poyA:
undetectable		 4fakA-3poyA:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HDL_A_DXCA75_0
(PPCA)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		4 / 8 ILE A 679
ILE A 527
PHE A 671
GLY A 304
 None
 0.85A 4hdlA-3poyA:
undetectable		 4hdlA-3poyA:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_1
(METHYLTRANSFERASE
MPPJ)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		3 / 3 ARG A 532
ASP A 669
ASP A 678
 None
 0.51A 4kicB-3poyA:
undetectable		 4kicB-3poyA:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NQA_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		6 / 11 ILE A 965
GLN A 955
PHE A 956
LEU A1076
ALA A1077
HIS A 986
 None
 1.28A 4nqaA-3poyA:
undetectable		 4nqaA-3poyA:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NQA_H_9CRH501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 12 ILE A 965
GLN A 955
LEU A1076
ALA A1077
HIS A 986
 None
 1.05A 4nqaH-3poyA:
undetectable		 4nqaH-3poyA:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_1
(PROTEASE)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 12 GLY A1178
ILE A1307
VAL A1212
VAL A1330
ILE A1305
 None
 0.86A 4q5mA-3poyA:
undetectable		 4q5mA-3poyA:
11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QI9_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 12 ILE A1230
ASP A1252
SER A1321
ILE A1177
LEU A1203
 None
 1.10A 4qi9A-3poyA:
undetectable		 4qi9A-3poyA:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QI9_B_MTXB201_1
(DIHYDROFOLATE
REDUCTASE)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 12 ILE A1230
ASP A1252
SER A1321
ILE A1177
LEU A1203
 None
 1.13A 4qi9B-3poyA:
undetectable		 4qi9B-3poyA:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QKN_A_JMSA602_1
(ALPHA-KETOGLUTARATE-
DEPENDENT
DIOXYGENASE FTO)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		4 / 8 LEU A 336
LEU A 338
VAL A 356
SER A 357
 None
 1.03A 4qknA-3poyA:
undetectable		 4qknA-3poyA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLE_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 11 ILE A1230
ASP A1252
SER A1321
ILE A1177
LEU A1203
 None
 1.15A 4qleB-3poyA:
undetectable		 4qleB-3poyA:
10.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_A_STRA601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		4 / 6 ALA A 927
ILE A 874
SER A 771
ILE A 925
 None
 0.68A 4r21A-3poyA:
undetectable		 4r21A-3poyA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_A_032A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		4 / 5 ILE A 559
VAL A 649
PHE A 564
HIS A 549
 None
 1.35A 4rzvA-3poyA:
undetectable		 4rzvA-3poyA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		4 / 7 LEU A1320
GLN A1319
PHE A1316
LEU A1188
 None
 0.87A 5b1aP-3poyA:
undetectable
5b1aW-3poyA:
undetectable		 5b1aP-3poyA:
13.35
5b1aW-3poyA:
6.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		4 / 7 LEU A1320
GLN A1319
PHE A1316
LEU A1188
 None
 0.90A 5b3sC-3poyA:
undetectable
5b3sJ-3poyA:
undetectable		 5b3sC-3poyA:
13.35
5b3sJ-3poyA:
6.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CXV_A_0HKA501_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		3 / 3 THR A 760
THR A 652
PHE A 650
 None
 0.63A 5cxvA-3poyA:
undetectable		 5cxvA-3poyA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		4 / 5 GLY A 690
PRO A 642
THR A 688
THR A 509
 None
 1.23A 5h5fA-3poyA:
undetectable		 5h5fA-3poyA:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HI6_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 12 ILE A1230
ASP A1252
SER A1321
ILE A1177
LEU A1203
 None
 1.14A 5hi6A-3poyA:
undetectable		 5hi6A-3poyA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_A_P06A801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		6 / 12 GLY A1155
PHE A1151
VAL A1344
ILE A1158
THR A1159
GLY A1309
 None
 1.27A 5hieA-3poyA:
undetectable		 5hieA-3poyA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_B_P06B801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		6 / 12 GLY A1155
PHE A1151
VAL A1344
ILE A1158
THR A1159
GLY A1309
 None
 1.27A 5hieB-3poyA:
undetectable		 5hieB-3poyA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_D_P06D801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		6 / 12 GLY A1155
PHE A1151
VAL A1344
ILE A1158
THR A1159
GLY A1309
 None
 1.27A 5hieD-3poyA:
undetectable		 5hieD-3poyA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_D_P06D801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		6 / 12 GLY A1155
PHE A1151
VAL A1344
VAL A1189
ILE A1158
THR A1159
 None
 1.34A 5hieD-3poyA:
undetectable		 5hieD-3poyA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_E_IPHE101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		4 / 7 ILE A1230
HIS A1204
LEU A1188
ALA A1186
 None
 0.94A 5hrqE-3poyA:
undetectable
5hrqF-3poyA:
undetectable
5hrqJ-3poyA:
undetectable		 5hrqE-3poyA:
1.90
5hrqF-3poyA:
2.88
5hrqJ-3poyA:
2.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		4 / 7 LEU A1320
GLN A1319
PHE A1316
LEU A1188
 None
 0.91A 5iy5C-3poyA:
undetectable
5iy5J-3poyA:
undetectable		 5iy5C-3poyA:
13.35
5iy5J-3poyA:
5.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_B_ASCB502_0
(OS09G0567300 PROTEIN)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		4 / 6 GLU A 535
GLY A 717
ARG A 715
ARG A 733
 None
 1.34A 5jcnB-3poyA:
undetectable		 5jcnB-3poyA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JI0_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 11 ILE A 965
GLN A 955
PHE A 956
LEU A1076
ALA A1077
 None
 1.19A 5ji0A-3poyA:
undetectable		 5ji0A-3poyA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_B_FUAB1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		4 / 5 ILE A1306
LEU A1175
HIS A1204
VAL A1187
 None
 0.87A 5jmnB-3poyA:
undetectable		 5jmnB-3poyA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_ACTA405_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		3 / 3 GLN A1302
THR A1170
ASP A1173
 None
 0.93A 5k9dA-3poyA:
undetectable		 5k9dA-3poyA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_E_PFLE406_1
(PROTON-GATED ION
CHANNEL)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 10 ILE A1341
ILE A1343
ILE A1307
ILE A1305
ILE A1306
 None
 1.11A 5murE-3poyA:
undetectable		 5murE-3poyA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_2
(SCRFP-TAG,GP41)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		4 / 7 GLN A 955
ASP A1080
ALA A 774
LEU A 794
 None
 1.09A 5nwvA-3poyA:
undetectable		 5nwvA-3poyA:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIG_A_EDTA501_0
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		4 / 6 ASN A 804
THR A 789
ARG A 791
GLU A 819
 None
 1.33A 5uigA-3poyA:
undetectable		 5uigA-3poyA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		3 / 3 ARG A1084
PHE A 954
LEU A1049
 None
 0.68A 5x1bC-3poyA:
undetectable		 5x1bC-3poyA:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_L_9CRL501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		6 / 12 ILE A 965
GLN A 955
PHE A 956
LEU A1076
ALA A1077
HIS A 986
 None
 1.37A 6a5zL-3poyA:
undetectable		 6a5zL-3poyA:
5.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DHB_A_BEZA202_0
(HEPATITIS A VIRUS
CELLULAR RECEPTOR 2)		 3poy NEUREXIN-1-ALPHA
(Bos
taurus) 		4 / 6 PHE A1299
ARG A1242
ASN A1326
ASP A1173
 None
 1.30A 6dhbA-3poyA:
undetectable		 6dhbA-3poyA:
8.07