SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pp2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_A_URFA2001_1
(URIDINE
PHOSPHORYLASE)		 3pp2 RHO
GTPASE-ACTIVATING
PROTEIN 27
(Homo
sapiens) 		5 / 10 GLY A 530
GLU A 528
LEU A 532
LEU A 561
ILE A 607
 None
 1.25A 3kvrA-3pp2A:
undetectable		 3kvrA-3pp2A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 3pp2 RHO
GTPASE-ACTIVATING
PROTEIN 27
(Homo
sapiens) 		5 / 10 GLY A 530
GLU A 528
LEU A 532
LEU A 561
ILE A 607
 None
 1.29A 3kvrB-3pp2A:
undetectable		 3kvrB-3pp2A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_A_URFA400_1
(URIDINE
PHOSPHORYLASE 1)		 3pp2 RHO
GTPASE-ACTIVATING
PROTEIN 27
(Homo
sapiens) 		5 / 9 GLY A 530
GLU A 528
LEU A 532
LEU A 561
ILE A 607
 None
 1.28A 3nbqA-3pp2A:
undetectable		 3nbqA-3pp2A:
16.77