SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ppo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_C_DVAC6_0
(GRAMICIDIN A)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		3 / 3 ALA A 216
VAL A 168
TRP A 172
 None
 0.81A 1av2C-3ppoA:
undetectable
1av2D-3ppoA:
undetectable		 1av2C-3ppoA:
5.46
1av2D-3ppoA:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DF7_A_MTXA501_1
(DIHYDROFOLATE
REDUCTASE)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		6 / 12 ALA A  48
PRO A 248
VAL A 251
LEU A 258
ILE A 262
TYR A 131
 None
 1.43A 1df7A-3ppoA:
undetectable		 1df7A-3ppoA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_A_DVAA6_0
(GRAMICIDIN C)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		3 / 3 ALA A  88
VAL A 246
TRP A 127
 None
 0.77A 1nt6A-3ppoA:
undetectable		 1nt6A-3ppoA:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_B_DVAB6_0
(GRAMICIDIN C)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		3 / 3 ALA A  88
VAL A 246
TRP A 127
 None
 0.77A 1nt6B-3ppoA:
undetectable		 1nt6B-3ppoA:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_C_DVAC6_0
(GRAMICIDIN D)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		3 / 3 ALA A 216
VAL A 168
TRP A 172
 None
 0.80A 1w5uC-3ppoA:
undetectable
1w5uD-3ppoA:
undetectable		 1w5uC-3ppoA:
5.46
1w5uD-3ppoA:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2888_0
(AMINOMETHYLTRANSFERA
SE)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 10 LEU A  61
GLU A 257
LEU A 258
ILE A  34
LEU A 252
 None
 1.24A 1wopA-3ppoA:
undetectable		 1wopA-3ppoA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_B_ACTB294_0
(GLYCINE
N-METHYLTRANSFERASE)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		4 / 6 ALA A  52
GLU A  56
ILE A  34
LEU A  65
 None
 0.75A 1xvaA-3ppoA:
undetectable
1xvaB-3ppoA:
undetectable		 1xvaA-3ppoA:
22.03
1xvaB-3ppoA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_C_H4BC1002_1
(HYPOTHETICAL PROTEIN
PH0634)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		4 / 6 ASP A 134
PHE A 133
THR A  89
GLU A  43
 None
 1.12A 2dttB-3ppoA:
undetectable
2dttC-3ppoA:
undetectable		 2dttB-3ppoA:
19.93
2dttC-3ppoA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_C_H4BC1002_1
(HYPOTHETICAL PROTEIN
PH0634)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		4 / 6 TYR A 203
ASP A 282
THR A 219
GLU A  43
 None
 1.44A 2dttB-3ppoA:
undetectable
2dttC-3ppoA:
undetectable		 2dttB-3ppoA:
19.93
2dttC-3ppoA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_F_TACF3888_1
(ELONGATION FACTOR
EF-TU)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		4 / 7 ASP A 129
SER A 244
VAL A 246
LEU A 100
 None
 1.05A 2hdnE-3ppoA:
undetectable
2hdnF-3ppoA:
undetectable
2hdnH-3ppoA:
undetectable		 2hdnE-3ppoA:
11.76
2hdnF-3ppoA:
22.19
2hdnH-3ppoA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_B_DVAB6_0
(GRAMICIDIN D)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		3 / 3 TRP A 127
ALA A  88
VAL A 246
 None
 0.74A 2izqA-3ppoA:
undetectable
2izqB-3ppoA:
undetectable		 2izqA-3ppoA:
5.46
2izqB-3ppoA:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_B_DVAB6_0
(GRAMICIDIN D)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		3 / 3 TRP A 172
ALA A 216
VAL A 168
 None
 0.72A 2izqA-3ppoA:
undetectable
2izqB-3ppoA:
undetectable		 2izqA-3ppoA:
5.46
2izqB-3ppoA:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		4 / 8 THR A  99
GLN A  77
ASP A  95
TYR A 125
 None
 0.91A 2xz5A-3ppoA:
undetectable
2xz5C-3ppoA:
undetectable		 2xz5A-3ppoA:
21.78
2xz5C-3ppoA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		4 / 5 ILE A 223
THR A 136
PHE A 238
PHE A 139
 None
 1.18A 3em0A-3ppoA:
undetectable		 3em0A-3ppoA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HBB_A_TMQA611_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 10 ALA A  64
ILE A 247
PRO A 248
LEU A 258
ILE A  55
 None
 1.14A 3hbbA-3ppoA:
undetectable		 3hbbA-3ppoA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 12 ILE A  55
THR A  63
VAL A 261
ILE A 262
ILE A  86
 None
 1.13A 3kpbA-3ppoA:
undetectable		 3kpbA-3ppoA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 12 ILE A  55
THR A  63
VAL A 261
ILE A 262
ILE A  86
 None
 1.16A 3kpbC-3ppoA:
undetectable		 3kpbC-3ppoA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_D_SAMD1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 10 ILE A  55
THR A  63
VAL A 261
ILE A 262
ILE A  86
 None
 1.15A 3kpbD-3ppoA:
undetectable		 3kpbD-3ppoA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_A_DVAA6_0
(GRAMICIDIN D)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		3 / 3 ALA A  88
VAL A 246
TRP A 127
 None
 0.73A 3l8lA-3ppoA:
undetectable
3l8lB-3ppoA:
undetectable		 3l8lA-3ppoA:
5.46
3l8lB-3ppoA:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_A_DVAA6_0
(GRAMICIDIN D)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		3 / 3 ALA A 216
VAL A 168
TRP A 172
 None
 0.74A 3l8lA-3ppoA:
undetectable
3l8lB-3ppoA:
undetectable		 3l8lA-3ppoA:
5.46
3l8lB-3ppoA:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_C_DVAC6_0
(GRAMICIDIN D)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		3 / 3 ALA A 216
VAL A 168
TRP A 172
 None
 0.84A 3l8lC-3ppoA:
undetectable
3l8lD-3ppoA:
undetectable		 3l8lC-3ppoA:
5.46
3l8lD-3ppoA:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 9 ILE A  34
ILE A  55
VAL A 251
ILE A 262
ILE A 247
 None
 1.23A 3p4wB-3ppoA:
undetectable		 3p4wB-3ppoA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 9 ILE A 262
ILE A 247
VAL A 261
ILE A  34
ILE A  55
 None
 1.18A 3p4wB-3ppoA:
undetectable		 3p4wB-3ppoA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 10 ILE A 262
ILE A 247
VAL A 261
ILE A  34
ILE A  55
 None
 1.18A 3p4wD-3ppoA:
undetectable		 3p4wD-3ppoA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 10 ILE A  34
ILE A  55
VAL A 251
ILE A 262
ILE A 247
 None
 1.23A 3p4wE-3ppoA:
undetectable		 3p4wE-3ppoA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 10 ILE A 262
ILE A 247
VAL A 261
ILE A  34
ILE A  55
 None
 1.19A 3p4wE-3ppoA:
undetectable		 3p4wE-3ppoA:
20.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PPO_A_DCKA401_0
(GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		9 / 9 GLN A  39
SER A  71
ASN A  72
TYR A  91
THR A  94
ASN A 135
TYR A 137
TYR A 217
TYR A 241
 DCK  A 401 (-3.0A)
DCK  A 401 (-4.4A)
DCK  A 401 (-4.2A)
DCK  A 401 (-3.8A)
DCK  A 401 (-3.7A)
DCK  A 401 (-4.2A)
DCK  A 401 (-3.5A)
DCK  A 401 (-3.9A)
DCK  A 401 (-4.1A)
 0.00A 3ppoA-3ppoA:
49.0		 3ppoA-3ppoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PPO_B_DCKB401_0
(GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		9 / 9 GLN A  39
SER A  71
ASN A  72
TYR A  91
THR A  94
ASN A 135
TYR A 137
TYR A 217
TYR A 241
 DCK  A 401 (-3.0A)
DCK  A 401 (-4.4A)
DCK  A 401 (-4.2A)
DCK  A 401 (-3.8A)
DCK  A 401 (-3.7A)
DCK  A 401 (-4.2A)
DCK  A 401 (-3.5A)
DCK  A 401 (-3.9A)
DCK  A 401 (-4.1A)
 0.21A 3ppoB-3ppoA:
46.0		 3ppoB-3ppoA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 12 ILE A 199
THR A  42
GLU A  43
ARG A 222
THR A 219
 None
 1.31A 3r75A-3ppoA:
undetectable		 3r75A-3ppoA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_B_BEZB701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 12 ILE A 199
THR A  42
GLU A  43
ARG A 222
THR A 219
 None
 1.30A 3r75B-3ppoA:
undetectable		 3r75B-3ppoA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R76_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 11 ILE A 199
THR A  42
GLU A  43
ARG A 222
THR A 219
 None
 1.30A 3r76A-3ppoA:
undetectable		 3r76A-3ppoA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R76_B_BEZB701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 11 ILE A 199
THR A  42
GLU A  43
ARG A 222
THR A 219
 None
 1.31A 3r76B-3ppoA:
undetectable		 3r76B-3ppoA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_F_9PLF1_1
(CYTOCHROME P450 2A13)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		4 / 8 PHE A 295
ALA A 292
PHE A 133
THR A  89
 None
 1.01A 3t3sF-3ppoA:
undetectable		 3t3sF-3ppoA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TPX_C_ACTC207_0
(E3 UBIQUITIN-PROTEIN
LIGASE MDM2)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		4 / 4 LYS A 109
PRO A 108
LEU A 112
ASN A 113
 None
 1.36A 3tpxC-3ppoA:
0.0		 3tpxC-3ppoA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		3 / 3 SER A  71
GLY A  70
GLN A  39
 DCK  A 401 (-4.4A)
None
DCK  A 401 (-3.0A)
 0.55A 3v4tH-3ppoA:
undetectable		 3v4tH-3ppoA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_B_RKEB401_1
(PROTON-GATED ION
CHANNEL)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		4 / 8 ASP A 234
ASP A 233
PHE A 189
LEU A 157
 None
 1.10A 4f8hB-3ppoA:
undetectable
4f8hC-3ppoA:
undetectable		 4f8hB-3ppoA:
20.17
4f8hC-3ppoA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HDL_A_DXCA75_0
(PPCA)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		4 / 8 ILE A 199
ILE A 223
LYS A 284
GLY A 283
 None
 0.97A 4hdlA-3ppoA:
undetectable		 4hdlA-3ppoA:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JVL_A_ESTA702_1
(ESTROGEN
SULFOTRANSFERASE)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		4 / 9 PHE A 133
CYH A 243
ILE A  51
MET A  50
 None
 1.16A 4jvlA-3ppoA:
undetectable		 4jvlA-3ppoA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NTX_A_AMRA509_1
(ACID-SENSING ION
CHANNEL 1
BASIC PHOSPHOLIPASE
A2 HOMOLOG TX-BETA)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		4 / 6 GLU A  45
ASP A 282
ASP A 220
ASN A 135
 None
None
None
DCK  A 401 (-4.2A)
 1.25A 4ntxA-3ppoA:
undetectable
4ntxC-3ppoA:
undetectable		 4ntxA-3ppoA:
22.49
4ntxC-3ppoA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX6_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 12 ALA A  48
ILE A 247
LEU A 258
ILE A 262
TYR A 131
 None
 1.13A 4nx6A-3ppoA:
undetectable		 4nx6A-3ppoA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX7_A_FOLA202_0
(DIHYDROFOLATE
REDUCTASE)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 12 ALA A  48
ILE A 247
LEU A 258
ILE A 262
TYR A 131
 None
 1.11A 4nx7A-3ppoA:
undetectable		 4nx7A-3ppoA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTH_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 12 ALA A  48
ILE A 247
LEU A 258
ILE A 262
TYR A 131
 None
 1.09A 4pthA-3ppoA:
undetectable		 4pthA-3ppoA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_D_HQED503_1
(CATALASE)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 9 ILE A  84
PRO A 248
GLN A  75
PHE A 119
ASP A  95
 None
 0.94A 4qopD-3ppoA:
undetectable		 4qopD-3ppoA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GLM_A_ACTA613_0
(GLYCOSIDE HYDROLASE
FAMILY 43)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		3 / 3 ASP A 233
SER A 155
TYR A 187
 None
 0.90A 5glmA-3ppoA:
undetectable		 5glmA-3ppoA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GPG_A_RAPA301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		5 / 11 TYR A 131
VAL A 246
ILE A 247
ALA A  52
ILE A  55
 None
 1.16A 5gpgA-3ppoA:
undetectable		 5gpgA-3ppoA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDZ_A_ADNA905_1
(ATP-CITRATE SYNTHASE)		 3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN
(Bacillus
subtilis) 		4 / 6 THR A  59
ASP A  60
LEU A  61
ASP A  32
 None
 1.20A 5tdzA-3ppoA:
undetectable		 5tdzA-3ppoA:
21.74