SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ppu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2434_1
(CHITINASE)		 3ppu GLUTATHIONE-S-TRANSF
ERASE
(Phanerochaete
chrysosporium) 		4 / 6 GLU A 235
TYR A 234
PHE A 242
ARG A 290
 None
 1.41A 2a3bB-3ppuA:
undetectable		 2a3bB-3ppuA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA502_0
(CHORISMATE SYNTHASE)		 3ppu GLUTATHIONE-S-TRANSF
ERASE
(Phanerochaete
chrysosporium) 		3 / 3 GLY A 154
ASP A 153
SER A  41
 None
 0.65A 2qhfA-3ppuA:
undetectable		 2qhfA-3ppuA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_A_ACTA207_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 3ppu GLUTATHIONE-S-TRANSF
ERASE
(Phanerochaete
chrysosporium) 		4 / 7 LEU A 144
LYS A 147
ASP A 133
ALA A 138
 None
 1.16A 3mbgA-3ppuA:
undetectable
3mbgB-3ppuA:
undetectable		 3mbgA-3ppuA:
16.47
3mbgB-3ppuA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SU9_A_ACTA426_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3ppu GLUTATHIONE-S-TRANSF
ERASE
(Phanerochaete
chrysosporium) 		3 / 3 GLN A  40
GLU A  38
LYS A  38
 None
 1.05A 3su9A-3ppuA:
undetectable		 3su9A-3ppuA:
24.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_E_CAME502_0
(CAMPHOR
5-MONOOXYGENASE)		 3ppu GLUTATHIONE-S-TRANSF
ERASE
(Phanerochaete
chrysosporium) 		4 / 5 PHE A 285
TYR A 223
PHE A  54
ILE A 333
 None
 0.78A 4jx1E-3ppuA:
undetectable		 4jx1E-3ppuA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 3ppu GLUTATHIONE-S-TRANSF
ERASE
(Phanerochaete
chrysosporium) 		3 / 3 ASN A 186
PHE A 181
TYR A  78
 None
 0.88A 4u15A-3ppuA:
undetectable		 4u15A-3ppuA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJE_A_TOYA202_1
(AADB)		 3ppu GLUTATHIONE-S-TRANSF
ERASE
(Phanerochaete
chrysosporium) 		4 / 8 TYR A 199
ASP A 208
GLU A 265
ILE A 178
 None
 0.95A 4xjeA-3ppuA:
0.7		 4xjeA-3ppuA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CFS_A_TOYA203_1
(AAD(2''),GENTAMICIN
2''-NUCLEOTIDYLTRANS
FERASE,GENTAMICIN
RESISTANCE PROTEIN)		 3ppu GLUTATHIONE-S-TRANSF
ERASE
(Phanerochaete
chrysosporium) 		4 / 8 TYR A 199
ASP A 208
GLU A 265
ILE A 178
 None
 0.96A 5cfsA-3ppuA:
0.8		 5cfsA-3ppuA:
19.01