SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ppx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJG_A_ADNA1501_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3ppx VON WILLEBRAND
FACTOR
(Homo
sapiens) 		4 / 7 ARG A1516
GLU A1523
PRO A1662
ALA A1661
 None
 1.36A 2ejgA-3ppxA:
undetectable		 2ejgA-3ppxA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A164_1
(BETA-LACTOGLOBULIN)		 3ppx VON WILLEBRAND
FACTOR
(Homo
sapiens) 		4 / 5 ASP A1663
LEU A1666
MET A1528
ARG A1527
 None
 1.33A 2gj5A-3ppxA:
undetectable		 2gj5A-3ppxA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_A_SAMA500_0
(HYPOTHETICAL PROTEIN)		 3ppx VON WILLEBRAND
FACTOR
(Homo
sapiens) 		4 / 7 ALA A1634
PHE A1520
PRO A1658
THR A1656
 None
 1.03A 2q6oA-3ppxA:
3.9		 2q6oA-3ppxA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_B_SAMB220_0
(16S RRNA METHYLASE)		 3ppx VON WILLEBRAND
FACTOR
(Homo
sapiens) 		5 / 12 GLY A1609
ALA A1661
GLU A1660
THR A1656
LEU A1657
 None
 0.95A 3mteB-3ppxA:
undetectable		 3mteB-3ppxA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_B_SAMB220_0
(16S RRNA METHYLASE)		 3ppx VON WILLEBRAND
FACTOR
(Homo
sapiens) 		5 / 12 GLY A1609
GLU A1660
PHE A1514
THR A1656
LEU A1657
 None
 0.96A 3mteB-3ppxA:
undetectable		 3mteB-3ppxA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_B_SAMB6735_0
(16S RRNA METHYLASE)		 3ppx VON WILLEBRAND
FACTOR
(Homo
sapiens) 		5 / 12 GLY A1609
ALA A1661
GLU A1660
THR A1656
LEU A1657
 None
 1.08A 3p2kB-3ppxA:
undetectable		 3p2kB-3ppxA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLB_A_TRPA901_0
(PROTEIN ARGONAUTE-2)		 3ppx VON WILLEBRAND
FACTOR
(Homo
sapiens) 		3 / 3 VAL A1499
ALA A1602
PHE A1552
 None
NA  A   1 ( 3.9A)
None
 0.66A 4olbA-3ppxA:
2.2		 4olbA-3ppxA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 3ppx VON WILLEBRAND
FACTOR
(Homo
sapiens) 		3 / 3 VAL A1499
ALA A1602
PHE A1552
 None
NA  A   1 ( 3.9A)
None
 0.69A 4w5nA-3ppxA:
5.4		 4w5nA-3ppxA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 3ppx VON WILLEBRAND
FACTOR
(Homo
sapiens) 		4 / 5 PHE A1501
VAL A1537
ALA A1500
PHE A1552
 None
 1.30A 4w5oA-3ppxA:
5.6		 4w5oA-3ppxA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3ppx VON WILLEBRAND
FACTOR
(Homo
sapiens) 		4 / 4 PHE A1501
VAL A1537
ALA A1500
PHE A1552
 None
 1.25A 4w5qA-3ppxA:
5.6		 4w5qA-3ppxA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_A_SALA801_1
(PROTEIN POLYBROMO-1)		 3ppx VON WILLEBRAND
FACTOR
(Homo
sapiens) 		4 / 7 ILE A1642
TYR A1542
ALA A1612
ILE A1616
 None
 0.79A 4y03A-3ppxA:
undetectable		 4y03A-3ppxA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 3ppx VON WILLEBRAND
FACTOR
(Homo
sapiens) 		4 / 5 PHE A1501
VAL A1537
ALA A1500
PHE A1552
 None
 1.31A 4z4cA-3ppxA:
5.4		 4z4cA-3ppxA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3ppx VON WILLEBRAND
FACTOR
(Homo
sapiens) 		4 / 5 PHE A1501
VAL A1537
ALA A1500
PHE A1552
 None
 1.30A 4z4dA-3ppxA:
5.5		 4z4dA-3ppxA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 3ppx VON WILLEBRAND
FACTOR
(Homo
sapiens) 		4 / 5 PHE A1501
VAL A1537
ALA A1500
PHE A1552
 None
 1.29A 4z4eA-3ppxA:
5.5		 4z4eA-3ppxA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3ppx VON WILLEBRAND
FACTOR
(Homo
sapiens) 		4 / 4 PHE A1501
VAL A1537
ALA A1500
PHE A1552
 None
 1.28A 4z4gA-3ppxA:
5.7		 4z4gA-3ppxA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 3ppx VON WILLEBRAND
FACTOR
(Homo
sapiens) 		3 / 3 VAL A1499
ALA A1602
PHE A1552
 None
NA  A   1 ( 3.9A)
None
 0.64A 4z4iA-3ppxA:
5.5		 4z4iA-3ppxA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGP_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 3ppx VON WILLEBRAND
FACTOR
(Homo
sapiens) 		5 / 12 MET A1528
ILE A1535
VAL A1524
GLU A1549
VAL A1665
 None
 1.14A 5igpA-3ppxA:
undetectable		 5igpA-3ppxA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS1_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3ppx VON WILLEBRAND
FACTOR
(Homo
sapiens) 		3 / 3 VAL A1499
ALA A1602
PHE A1552
 None
NA  A   1 ( 3.9A)
None
 0.66A 5js1A-3ppxA:
undetectable		 5js1A-3ppxA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KI6_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3ppx VON WILLEBRAND
FACTOR
(Homo
sapiens) 		4 / 4 PHE A1501
VAL A1537
ALA A1500
PHE A1552
 None
 1.27A 5ki6A-3ppxA:
5.4		 5ki6A-3ppxA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		 3ppx VON WILLEBRAND
FACTOR
(Homo
sapiens) 		4 / 7 PRO A1632
PHE A1654
SER A1506
ASN A1610
 None
 1.16A 5l1fC-3ppxA:
5.8		 5l1fC-3ppxA:
12.77