SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pqd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CET_A_CLQA1001_0
(PROTEIN (L-LACTATE
DEHYDROGENASE))		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 9 GLY A  12
ASP A  37
TYR A  68
ALA A  81
ILE A 101
 None
 0.67A 1cetA-3pqdA:
40.9		 1cetA-3pqdA:
32.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 12 LEU A  50
GLY A  53
VAL A  35
SER A  19
PHE A  15
 None
 1.12A 1dfoA-3pqdA:
undetectable		 1dfoA-3pqdA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_B_FFOB2002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 12 LEU A  50
GLY A  53
VAL A  35
SER A  19
PHE A  15
 None
 1.12A 1dfoB-3pqdA:
undetectable		 1dfoB-3pqdA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 12 LEU A  50
GLY A  53
VAL A  35
SER A  19
PHE A  15
 None
 1.12A 1dfoC-3pqdA:
undetectable		 1dfoC-3pqdA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_D_FFOD4002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 12 LEU A  50
GLY A  53
VAL A  35
SER A  19
PHE A  15
 None
 1.12A 1dfoD-3pqdA:
undetectable		 1dfoD-3pqdA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 12 LEU A  50
GLY A  53
VAL A  35
SER A  19
PHE A  15
 None
 1.15A 1eqbB-3pqdA:
undetectable		 1eqbB-3pqdA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 12 LEU A  50
GLY A  53
VAL A  35
SER A  19
PHE A  15
 None
 1.16A 1eqbD-3pqdA:
undetectable		 1eqbD-3pqdA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_1
(HIV-II PROTEASE)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		6 / 12 GLY A 266
ALA A 267
ASP A 268
GLY A 304
ILE A 175
ILE A 272
 None
 1.42A 1hshA-3pqdA:
undetectable		 1hshA-3pqdA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_1
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		4 / 4 ILE A 243
LEU A 240
VAL A 236
ALA A 231
 None
 0.85A 1mz9A-3pqdA:
undetectable		 1mz9A-3pqdA:
9.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		4 / 5 ILE A 243
LEU A 240
VAL A 236
ALA A 231
 None
 0.84A 1mz9C-3pqdA:
undetectable		 1mz9C-3pqdA:
9.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_C_TRPC81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 9 GLY A 145
THR A 149
HIS A 178
ILE A 144
SER A 239
 None
 1.44A 1utdC-3pqdA:
undetectable
1utdD-3pqdA:
undetectable		 1utdC-3pqdA:
12.85
1utdD-3pqdA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 10 GLY A 145
THR A 149
HIS A 178
ILE A 144
SER A 239
 None
 1.35A 1utdR-3pqdA:
undetectable
1utdS-3pqdA:
undetectable		 1utdR-3pqdA:
12.85
1utdS-3pqdA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COJ_A_GBNA420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 11 PHE A 299
THR A 259
GLY A 147
THR A 148
TYR A 265
 None
 1.06A 2cojA-3pqdA:
undetectable
2cojB-3pqdA:
undetectable		 2cojA-3pqdA:
24.18
2cojB-3pqdA:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EFJ_A_37TA502_1
(3,7-DIMETHYLXANTHINE
METHYLTRANSFERASE)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 12 LEU A  24
ILE A 243
ILE A 144
ILE A  76
TYR A  20
 None
 1.46A 2efjA-3pqdA:
4.7		 2efjA-3pqdA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_H_TACH4888_1
(ELONGATION FACTOR
EF-TU)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		4 / 7 VAL A 185
LEU A 261
SER A 152
ASP A 151
 None
 1.03A 2hdnF-3pqdA:
2.9
2hdnG-3pqdA:
undetectable
2hdnH-3pqdA:
4.7		 2hdnF-3pqdA:
22.75
2hdnG-3pqdA:
9.82
2hdnH-3pqdA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		3 / 3 TYR A 233
GLY A  17
PHE A  15
 None
 0.65A 2m2pB-3pqdA:
undetectable		 2m2pB-3pqdA:
7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_FFOA505_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 12 LEU A 291
HIS A 188
LEU A 289
SER A 187
GLY A 176
 None
 1.35A 2vmyB-3pqdA:
2.4		 2vmyB-3pqdA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		3 / 3 SER A 239
GLU A 182
ASP A 216
 None
 0.70A 2zulA-3pqdA:
6.5		 2zulA-3pqdA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		3 / 3 SER A 239
GLU A 182
ASP A 216
 None
 0.68A 3dmhA-3pqdA:
6.4		 3dmhA-3pqdA:
26.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_B_ERYB195_0
(REPRESSOR PROTEIN
MPHR(A))		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 12 GLY A 235
TYR A  20
LEU A 119
SER A 152
ILE A 144
 None
 1.04A 3frqB-3pqdA:
undetectable		 3frqB-3pqdA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA304_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		4 / 4 GLN A  59
PRO A  60
VAL A  61
GLU A  32
 None
 1.02A 3huoA-3pqdA:
undetectable		 3huoA-3pqdA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_D_ACTD229_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		4 / 4 ASP A  46
GLY A  45
LYS A  42
GLU A  41
 None
 1.48A 3hznD-3pqdA:
undetectable		 3hznD-3pqdA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 10 LEU A 183
SER A 302
ILE A 175
SER A 258
GLY A 273
 None
 1.22A 3ijxB-3pqdA:
undetectable
3ijxD-3pqdA:
undetectable		 3ijxB-3pqdA:
22.85
3ijxD-3pqdA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB262_1
(GLUTAMATE RECEPTOR 2)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 10 ILE A 175
SER A 258
GLY A 273
LEU A 183
SER A 302
 None
 1.16A 3ik6B-3pqdA:
undetectable
3ik6E-3pqdA:
undetectable		 3ik6B-3pqdA:
22.85
3ik6E-3pqdA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 10 LEU A 183
SER A 302
ILE A 175
SER A 258
GLY A 273
 None
 1.18A 3ik6B-3pqdA:
undetectable
3ik6E-3pqdA:
undetectable		 3ik6B-3pqdA:
22.85
3ik6E-3pqdA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_B_HFZB800_1
(GLUTAMATE RECEPTOR 2)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 10 LEU A 183
SER A 302
ILE A 175
SER A 258
GLY A 273
 None
 1.18A 3iluB-3pqdA:
undetectable
3iluE-3pqdA:
undetectable		 3iluB-3pqdA:
22.85
3iluE-3pqdA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_E_HFZE800_1
(GLUTAMATE RECEPTOR 2)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 11 ILE A 175
SER A 258
GLY A 273
LEU A 183
SER A 302
 None
 1.17A 3iluB-3pqdA:
undetectable
3iluE-3pqdA:
undetectable		 3iluB-3pqdA:
22.85
3iluE-3pqdA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5S_A_ACHA1289_0
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		4 / 6 VAL A   8
ASN A   6
TYR A  20
ILE A 247
 None
 1.17A 3q5sA-3pqdA:
undetectable		 3q5sA-3pqdA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		4 / 5 HIS A 178
THR A 149
GLU A 182
ASP A 216
 None
 0.96A 3tm4A-3pqdA:
8.1		 3tm4A-3pqdA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		4 / 5 HIS A 178
THR A 149
GLU A 182
ASP A 216
 None
 0.94A 3tm4B-3pqdA:
8.1		 3tm4B-3pqdA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		4 / 5 TYR A 233
VAL A  16
SER A  19
GLY A 235
 None
 1.48A 3v4tA-3pqdA:
undetectable
3v4tD-3pqdA:
undetectable		 3v4tA-3pqdA:
21.99
3v4tD-3pqdA:
21.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OKN_B_KANB403_1
(L-LACTATE
DEHYDROGENASE A
CHAIN)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		6 / 9 ASP A  37
VAL A  38
TYR A  68
ALA A  81
ILE A 101
ILE A 105
 None
 0.62A 4oknB-3pqdA:
42.6		 4oknB-3pqdA:
38.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 10 GLY A 145
THR A 149
HIS A 178
ILE A 144
SER A 239
 None
 1.36A 5eeuN-3pqdA:
undetectable
5eeuO-3pqdA:
undetectable		 5eeuN-3pqdA:
12.85
5eeuO-3pqdA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 10 GLY A 145
THR A 149
HIS A 178
ILE A 144
SER A 239
 None
 1.36A 5eevN-3pqdA:
undetectable
5eevO-3pqdA:
undetectable		 5eevN-3pqdA:
12.85
5eevO-3pqdA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 10 GLY A 145
THR A 149
HIS A 178
ILE A 144
SER A 239
 None
 1.36A 5eewN-3pqdA:
undetectable
5eewO-3pqdA:
undetectable		 5eewN-3pqdA:
12.85
5eewO-3pqdA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 10 GLY A 145
THR A 149
HIS A 178
ILE A 144
SER A 239
 None
 1.36A 5eexN-3pqdA:
undetectable
5eexO-3pqdA:
undetectable		 5eexN-3pqdA:
12.85
5eexO-3pqdA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 10 GLY A 145
THR A 149
HIS A 178
ILE A 144
SER A 239
 None
 1.36A 5eeyN-3pqdA:
undetectable
5eeyO-3pqdA:
undetectable		 5eeyN-3pqdA:
12.85
5eeyO-3pqdA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 10 GLY A 145
THR A 149
HIS A 178
ILE A 144
SER A 239
 None
 1.36A 5eezN-3pqdA:
undetectable
5eezO-3pqdA:
undetectable		 5eezN-3pqdA:
12.85
5eezO-3pqdA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 10 GLY A 145
THR A 149
HIS A 178
ILE A 144
SER A 239
 None
 1.37A 5ef0N-3pqdA:
undetectable
5ef0O-3pqdA:
undetectable		 5ef0N-3pqdA:
12.85
5ef0O-3pqdA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 10 GLY A 145
THR A 149
HIS A 178
ILE A 144
SER A 239
 None
 1.37A 5ef1N-3pqdA:
undetectable
5ef1O-3pqdA:
undetectable		 5ef1N-3pqdA:
12.85
5ef1O-3pqdA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 10 GLY A 145
THR A 149
HIS A 178
ILE A 144
SER A 239
 None
 1.37A 5ef2N-3pqdA:
undetectable
5ef2O-3pqdA:
undetectable		 5ef2N-3pqdA:
12.85
5ef2O-3pqdA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 10 GLY A 145
THR A 149
HIS A 178
ILE A 144
SER A 239
 None
 1.37A 5ef3N-3pqdA:
undetectable
5ef3O-3pqdA:
undetectable		 5ef3N-3pqdA:
12.85
5ef3O-3pqdA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 12 GLY A 192
ASN A 190
PHE A 155
ARG A 156
ALA A 172
 None
 0.91A 5ih0A-3pqdA:
undetectable		 5ih0A-3pqdA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3pqd L-LACTATE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 12 GLY A 193
ASN A 190
PHE A 155
ARG A 156
ALA A 172
 None
 1.19A 5ih0A-3pqdA:
undetectable		 5ih0A-3pqdA:
23.62