SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pqj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I89_A_1FLA201_1
(TRANSTHYRETIN)		 3pqj BIOFILM
GROWTH-ASSOCIATED
REPRESSOR
(Xylella
fastidiosa) 		4 / 6 LEU A  72
LEU A  69
SER A  66
THR A  64
 None
 1.01A 4i89A-3pqjA:
undetectable		 4i89A-3pqjA:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_A_4TXA201_1
(TRANSTHYRETIN)		 3pqj BIOFILM
GROWTH-ASSOCIATED
REPRESSOR
(Xylella
fastidiosa) 		4 / 6 LEU A  72
LEU A  69
SER A  66
THR A  64
 None
 0.98A 5bojA-3pqjA:
undetectable		 5bojA-3pqjA:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_B_4TXB201_1
(TRANSTHYRETIN)		 3pqj BIOFILM
GROWTH-ASSOCIATED
REPRESSOR
(Xylella
fastidiosa) 		4 / 7 LEU A  72
LEU A  69
SER A  66
THR A  64
 None
 1.02A 5bojB-3pqjA:
undetectable		 5bojB-3pqjA:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_A_6J3A201_0
(TRANSTHYRETIN)		 3pqj BIOFILM
GROWTH-ASSOCIATED
REPRESSOR
(Xylella
fastidiosa) 		4 / 6 LEU A  72
LEU A  69
SER A  66
THR A  64
 None
 1.01A 5l4iA-3pqjA:
undetectable		 5l4iA-3pqjA:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_B_6J3B201_0
(TRANSTHYRETIN)		 3pqj BIOFILM
GROWTH-ASSOCIATED
REPRESSOR
(Xylella
fastidiosa) 		4 / 6 LEU A  72
LEU A  69
SER A  66
THR A  64
 None
 1.01A 5l4iB-3pqjA:
undetectable		 5l4iB-3pqjA:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QSA615_1
(SERUM ALBUMIN)		 3pqj BIOFILM
GROWTH-ASSOCIATED
REPRESSOR
(Xylella
fastidiosa) 		4 / 8 LEU A  38
VAL A  41
LEU A  29
ILE A  77
 None
 0.95A 5v0vA-3pqjA:
undetectable		 5v0vA-3pqjA:
10.46