SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pqu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 3pqu TRANSFERRIN BINDING
PROTEIN B
(Actinobacillus
suis) 		5 / 12 LEU A 302
PHE A 306
PHE A 329
GLY A 305
GLY A 279
 None
 1.14A 1fe2A-3pquA:
undetectable		 1fe2A-3pquA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_C_CCSC47_0
(GLUTATHIONE
S-TRANSFERASE)		 3pqu TRANSFERRIN BINDING
PROTEIN B
(Actinobacillus
suis) 		4 / 6 THR A  48
GLY A 305
LYS A 317
TYR A 162
 None
 0.81A 1gtiC-3pquA:
undetectable		 1gtiC-3pquA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_F_CCSF47_0
(GLUTATHIONE
S-TRANSFERASE)		 3pqu TRANSFERRIN BINDING
PROTEIN B
(Actinobacillus
suis) 		4 / 5 THR A  48
GLY A 305
LYS A 317
TYR A 162
 None
 1.30A 1gtiF-3pquA:
undetectable		 1gtiF-3pquA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_B_MTXB609_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 3pqu TRANSFERRIN BINDING
PROTEIN B
(Actinobacillus
suis) 		5 / 12 ALA A 567
LEU A 428
PHE A 409
THR A 474
LEU A 404
 None
 1.30A 2oipB-3pquA:
undetectable		 2oipB-3pquA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_C_QPSC1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3pqu TRANSFERRIN BINDING
PROTEIN B
(Actinobacillus
suis) 		5 / 12 VAL A 478
PHE A 476
ASN A 541
VAL A 540
GLY A 512
 None
 1.16A 2x2iC-3pquA:
2.8		 2x2iC-3pquA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3pqu TRANSFERRIN BINDING
PROTEIN B
(Actinobacillus
suis) 		5 / 10 GLU A 136
ILE A 212
GLY A 202
LEU A  79
ILE A  55
 None
 1.46A 3adsA-3pquA:
undetectable		 3adsA-3pquA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGX_A_SALA102_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 3pqu TRANSFERRIN BINDING
PROTEIN B
(Actinobacillus
suis) 		4 / 7 VAL A 133
ILE A  55
TYR A 159
ILE A 160
 None
 1.04A 3hgxA-3pquA:
undetectable		 3hgxA-3pquA:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA604_0
(GBAA_1210 PROTEIN)		 3pqu TRANSFERRIN BINDING
PROTEIN B
(Actinobacillus
suis) 		4 / 6 TYR A 161
GLY A 131
HIS A 112
SER A 113
 None
 1.11A 3tj7A-3pquA:
undetectable
3tj7B-3pquA:
undetectable		 3tj7A-3pquA:
15.41
3tj7B-3pquA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC606_0
(GBAA_1210 PROTEIN)		 3pqu TRANSFERRIN BINDING
PROTEIN B
(Actinobacillus
suis) 		4 / 6 TYR A 161
GLY A 131
HIS A 112
SER A 113
 None
 1.12A 3tj7C-3pquA:
undetectable
3tj7D-3pquA:
2.7		 3tj7C-3pquA:
15.41
3tj7D-3pquA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_D_ACTD605_0
(GBAA_1210 PROTEIN)		 3pqu TRANSFERRIN BINDING
PROTEIN B
(Actinobacillus
suis) 		4 / 6 HIS A 112
SER A 113
TYR A 161
GLY A 131
 None
 1.13A 3tj7C-3pquA:
undetectable
3tj7D-3pquA:
2.7		 3tj7C-3pquA:
15.41
3tj7D-3pquA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_1
(ADENOSINE KINASE,
PUTATIVE)		 3pqu TRANSFERRIN BINDING
PROTEIN B
(Actinobacillus
suis) 		5 / 12 ASN A 541
ILE A 349
GLY A 553
GLY A 554
THR A 347
 None
 0.86A 3uq6A-3pquA:
undetectable		 3uq6A-3pquA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 3pqu TRANSFERRIN BINDING
PROTEIN B
(Actinobacillus
suis) 		5 / 12 ASN A 541
ILE A 349
GLY A 553
GLY A 554
THR A 347
 None
 0.86A 3vaqA-3pquA:
undetectable		 3vaqA-3pquA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 3pqu TRANSFERRIN BINDING
PROTEIN B
(Actinobacillus
suis) 		5 / 12 ASN A 541
ILE A 349
GLY A 553
GLY A 554
THR A 347
 None
 0.84A 3vasA-3pquA:
undetectable		 3vasA-3pquA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_A_CAMA423_0
(CYTOCHROME P450)		 3pqu TRANSFERRIN BINDING
PROTEIN B
(Actinobacillus
suis) 		5 / 12 THR A 433
GLY A 553
VAL A 478
ILE A 505
VAL A 485
 None
 1.07A 4c9oA-3pquA:
undetectable		 4c9oA-3pquA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_B_CAMB423_0
(CYTOCHROME P450)		 3pqu TRANSFERRIN BINDING
PROTEIN B
(Actinobacillus
suis) 		5 / 12 THR A 433
GLY A 553
VAL A 478
ILE A 505
VAL A 485
 None
 1.07A 4c9oB-3pquA:
undetectable		 4c9oB-3pquA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 3pqu TRANSFERRIN BINDING
PROTEIN B
(Actinobacillus
suis) 		5 / 10 THR A 433
GLY A 553
VAL A 478
ILE A 505
VAL A 485
 None
 1.11A 4jx1B-3pquA:
undetectable		 4jx1B-3pquA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOU_A_C04A207_1
(UNCHARACTERIZED
PROTEIN)		 3pqu TRANSFERRIN BINDING
PROTEIN B
(Actinobacillus
suis) 		3 / 3 GLY A 487
GLU A 475
THR A 474
 None
 0.56A 4kouA-3pquA:
undetectable		 4kouA-3pquA:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM9_A_FVXA603_1
(TRANSPORTER)		 3pqu TRANSFERRIN BINDING
PROTEIN B
(Actinobacillus
suis) 		5 / 11 VAL A 485
ALA A 503
GLY A 570
GLY A 542
ASP A 477
 None
 1.29A 4mm9A-3pquA:
undetectable		 4mm9A-3pquA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YSH_B_GLYB401_0
(GLYCINE OXIDASE)		 3pqu TRANSFERRIN BINDING
PROTEIN B
(Actinobacillus
suis) 		4 / 6 GLY A 164
TYR A 162
ALA A 315
ARG A 281
 None
 1.30A 4yshB-3pquA:
undetectable		 4yshB-3pquA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_I_BEZI1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 3pqu TRANSFERRIN BINDING
PROTEIN B
(Actinobacillus
suis) 		3 / 3 SER A 130
TYR A 162
TYR A 161
 None
 0.54A 5lakA-3pquA:
undetectable
5lakI-3pquA:
undetectable		 5lakA-3pquA:
19.76
5lakI-3pquA:
1.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_J_BEZJ1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 3pqu TRANSFERRIN BINDING
PROTEIN B
(Actinobacillus
suis) 		3 / 3 SER A 130
TYR A 162
TYR A 161
 None
 0.55A 5lakC-3pquA:
undetectable
5lakJ-3pquA:
undetectable		 5lakC-3pquA:
19.76
5lakJ-3pquA:
1.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_0
(REGULATORY PROTEIN
TETR)		 3pqu TRANSFERRIN BINDING
PROTEIN B
(Actinobacillus
suis) 		5 / 12 ALA A 330
SER A 238
GLU A 239
LEU A 253
ILE A 273
 None
 1.41A 5vlmA-3pquA:
undetectable		 5vlmA-3pquA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_B_BEZB201_0
(NS3 PROTEASE)		 3pqu TRANSFERRIN BINDING
PROTEIN B
(Actinobacillus
suis) 		4 / 5 HIS A 114
ALA A 330
SER A 130
GLY A 131
 None
 1.24A 5yodB-3pquA:
undetectable		 5yodB-3pquA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_D_BEZD201_0
(NS3 PROTEASE)		 3pqu TRANSFERRIN BINDING
PROTEIN B
(Actinobacillus
suis) 		4 / 5 HIS A 114
ALA A 330
SER A 130
GLY A 131
 None
 1.10A 5yodD-3pquA:
undetectable		 5yodD-3pquA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ1_B_AB1B201_1
(HIV-1 PROTEASE)		 3pqu TRANSFERRIN BINDING
PROTEIN B
(Actinobacillus
suis) 		5 / 12 GLY A 512
ALA A 503
VAL A 478
ILE A 505
GLY A 509
 None
 0.95A 6dj1B-3pquA:
undetectable		 6dj1B-3pquA:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_0
(STIE PROTEIN)		 3pqu TRANSFERRIN BINDING
PROTEIN B
(Actinobacillus
suis) 		5 / 12 LEU A 195
GLY A 202
GLY A 204
ILE A  55
ILE A 212
 None
 1.02A 6ecxA-3pquA:
undetectable		 6ecxA-3pquA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA605_0
(SERUM ALBUMIN)		 3pqu TRANSFERRIN BINDING
PROTEIN B
(Actinobacillus
suis) 		4 / 8 LEU A  49
GLY A  50
LEU A 163
GLU A  90
 None
None
None
GOL  A 579 (-2.8A)
 0.73A 6mdqA-3pquA:
undetectable		 6mdqA-3pquA:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_0
(PEPTIDYLPROLYL
ISOMERASE)		 3pqu TRANSFERRIN BINDING
PROTEIN B
(Actinobacillus
suis) 		4 / 4 ASP A 115
ILE A  95
PRO A  96
LEU A  98
 None
None
GOL  A 578 ( 4.4A)
None
 1.17A 6mkeB-3pquA:
undetectable		 6mkeB-3pquA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_0
(PEPTIDYLPROLYL
ISOMERASE)		 3pqu TRANSFERRIN BINDING
PROTEIN B
(Actinobacillus
suis) 		4 / 4 ASP A 115
ILE A  95
PRO A  96
LEU A  98
 None
None
GOL  A 578 ( 4.4A)
None
 1.28A 6mkeA-3pquA:
undetectable		 6mkeA-3pquA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3pqu TRANSFERRIN BINDING
PROTEIN B
(Actinobacillus
suis) 		3 / 3 ARG A 432
PHE A 409
PHE A 510
 None
 1.01A 6nknC-3pquA:
undetectable
6nknJ-3pquA:
undetectable		 6nknC-3pquA:
18.91
6nknJ-3pquA:
8.07