SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pr1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9J_H_TESH1010_1
(RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT HEAVY
CHAIN
RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT LIGHT
CHAIN)		 3pr1 PROBABLE GTP-BINDING
PROTEIN ENGB
(Thermotoga
maritima) 		5 / 11 TYR A  64
GLU A  25
GLY A  24
LEU A  22
VAL A   6
 None
 1.41A 1i9jH-3pr1A:
undetectable
1i9jL-3pr1A:
undetectable		 1i9jH-3pr1A:
22.36
1i9jL-3pr1A:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3pr1 PROBABLE GTP-BINDING
PROTEIN ENGB
(Thermotoga
maritima) 		4 / 7 PHE A  99
LEU A 110
VAL A  29
GLY A  30
 None
 1.01A 1t88A-3pr1A:
undetectable		 1t88A-3pr1A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_E_TOPE1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 3pr1 PROBABLE GTP-BINDING
PROTEIN ENGB
(Thermotoga
maritima) 		4 / 8 ALA A  27
LEU A 105
ILE A  61
PHE A  63
 None
 0.83A 2w9sE-3pr1A:
undetectable		 2w9sE-3pr1A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_B_VD3B700_1
(CYTOCHROME P450 2R1)		 3pr1 PROBABLE GTP-BINDING
PROTEIN ENGB
(Thermotoga
maritima) 		5 / 12 LEU A 105
VAL A  66
GLY A  24
GLU A  25
THR A 137
 None
 1.13A 3c6gB-3pr1A:
undetectable		 3c6gB-3pr1A:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DO3_A_0LAA602_1
(FATTY-ACID AMIDE
HYDROLASE 1)		 3pr1 PROBABLE GTP-BINDING
PROTEIN ENGB
(Thermotoga
maritima) 		4 / 5 LEU A 184
LEU A 187
MET A 107
THR A 169
 None
 1.09A 4do3A-3pr1A:
undetectable		 4do3A-3pr1A:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 3pr1 PROBABLE GTP-BINDING
PROTEIN ENGB
(Thermotoga
maritima) 		4 / 5 TYR A  18
PRO A  20
GLU A  25
TYR A  71
 None
 1.43A 4w5tA-3pr1A:
3.3		 4w5tA-3pr1A:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3pr1 PROBABLE GTP-BINDING
PROTEIN ENGB
(Thermotoga
maritima) 		4 / 5 ARG A 115
MET A 143
THR A 141
LEU A 140
 None
 1.42A 5x19J-3pr1A:
undetectable		 5x19J-3pr1A:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3pr1 PROBABLE GTP-BINDING
PROTEIN ENGB
(Thermotoga
maritima) 		4 / 5 ARG A 115
MET A 143
THR A 141
LEU A 140
 None
 1.46A 5x1bJ-3pr1A:
undetectable		 5x1bJ-3pr1A:
14.94