SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pr6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3pr6 TRAPP-ASSOCIATED
PROTEIN TCA17
(Saccharomyces
cerevisiae) 		4 / 6 LEU A   3
ILE A 105
ILE A  79
LEU A  10
 None
None
CL  A 158 ( 4.5A)
None
 0.96A 2xkwB-3pr6A:
undetectable		 2xkwB-3pr6A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_A_08JA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 3pr6 TRAPP-ASSOCIATED
PROTEIN TCA17
(Saccharomyces
cerevisiae) 		4 / 8 VAL A   8
LEU A  10
LEU A  19
ILE A 115
 None
 0.88A 3u5kA-3pr6A:
undetectable		 3u5kA-3pr6A:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_B_08JB2_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 3pr6 TRAPP-ASSOCIATED
PROTEIN TCA17
(Saccharomyces
cerevisiae) 		4 / 7 VAL A   8
LEU A  10
LEU A  19
ILE A 115
 None
 0.96A 3u5kB-3pr6A:
undetectable		 3u5kB-3pr6A:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_C_08JC3_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 3pr6 TRAPP-ASSOCIATED
PROTEIN TCA17
(Saccharomyces
cerevisiae) 		4 / 8 VAL A   8
LEU A  10
LEU A  19
ILE A 115
 None
 0.86A 3u5kC-3pr6A:
undetectable		 3u5kC-3pr6A:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_A_TYLA1188_1
(BROMODOMAIN
CONTAINING 2)		 3pr6 TRAPP-ASSOCIATED
PROTEIN TCA17
(Saccharomyces
cerevisiae) 		4 / 5 VAL A   8
LEU A  10
LEU A  19
ILE A 115
 None
 0.94A 4a9jA-3pr6A:
undetectable		 4a9jA-3pr6A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_B_TYLB1187_1
(BROMODOMAIN
CONTAINING 2)		 3pr6 TRAPP-ASSOCIATED
PROTEIN TCA17
(Saccharomyces
cerevisiae) 		4 / 5 VAL A   8
LEU A  10
LEU A  19
ILE A 115
 None
 0.92A 4a9jB-3pr6A:
undetectable		 4a9jB-3pr6A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_A_TLFA300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)		 3pr6 TRAPP-ASSOCIATED
PROTEIN TCA17
(Saccharomyces
cerevisiae) 		5 / 12 PHE A  90
VAL A  72
PHE A   7
VAL A 112
PHE A 109
 None
CSO  A   6 ( 4.5A)
None
None
None
 1.30A 6ap6A-3pr6A:
undetectable		 6ap6A-3pr6A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_B_TLFB300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)		 3pr6 TRAPP-ASSOCIATED
PROTEIN TCA17
(Saccharomyces
cerevisiae) 		5 / 12 PHE A  90
VAL A  72
PHE A   7
VAL A 112
PHE A 109
 None
CSO  A   6 ( 4.5A)
None
None
None
 1.32A 6ap6B-3pr6A:
undetectable		 6ap6B-3pr6A:
22.43