SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pr7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 3pr7 USPA1
(Moraxella
catarrhalis) 		5 / 12 GLY A 106
GLY A 120
GLY A 119
GLY A  75
ASN A  63
 None
 0.92A 1n2xB-3pr7A:
undetectable		 1n2xB-3pr7A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA602_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 3pr7 USPA1
(Moraxella
catarrhalis) 		4 / 7 ASN A 216
ALA A 222
ALA A 208
GLN A 200
 None
 0.86A 3a2qA-3pr7A:
undetectable		 3a2qA-3pr7A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3pr7 USPA1
(Moraxella
catarrhalis) 		5 / 12 GLY A 224
ASN A 227
ILE A 237
GLY A 270
SER A 255
 None
 1.02A 3hs6B-3pr7A:
undetectable		 3hs6B-3pr7A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3007_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3pr7 USPA1
(Moraxella
catarrhalis) 		5 / 9 ASN A 272
THR A 273
ALA A 274
LEU A 268
ASN A 241
 None
 1.45A 3kp6B-3pr7A:
undetectable		 3kp6B-3pr7A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIK_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 3pr7 USPA1
(Moraxella
catarrhalis) 		5 / 12 GLY A 121
ASN A 139
GLY A 104
SER A 105
GLY A 150
 None
 0.91A 5hikA-3pr7A:
undetectable		 5hikA-3pr7A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_A_SAMA401_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3pr7 USPA1
(Moraxella
catarrhalis) 		5 / 12 LEU A  92
GLY A  76
GLY A  60
GLY A  90
GLY A  91
 None
 1.07A 5wyqA-3pr7A:
undetectable		 5wyqA-3pr7A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA606_0
(ALPHA-AMYLASE)		 3pr7 USPA1
(Moraxella
catarrhalis) 		5 / 7 GLY A 135
GLY A 136
GLY A 152
GLY A 167
GLY A 166
 None
 0.84A 6ag0A-3pr7A:
undetectable		 6ag0A-3pr7A:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA606_0
(ALPHA-AMYLASE)		 3pr7 USPA1
(Moraxella
catarrhalis) 		5 / 7 GLY A 151
GLY A 150
GLY A 134
GLY A 119
GLY A 120
 None
 1.08A 6ag0A-3pr7A:
undetectable		 6ag0A-3pr7A:
14.79