SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3prh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		3 / 3 SER A 294
GLU A 295
GLU A 296
 None
 0.68A 1eqbD-3prhA:
undetectable		 1eqbD-3prhA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		3 / 3 SER A 294
GLU A 295
GLU A 296
 None
 0.68A 1eqbB-3prhA:
undetectable		 1eqbB-3prhA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_B_CHDB701_0
(FERROCHELATASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		3 / 3 LYS A 193
GLY A 145
PRO A 144
 None
 0.90A 2hreB-3prhA:
undetectable		 2hreB-3prhA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		5 / 11 TYR A  37
GLY A 304
ALA A 305
ASN A 313
ALA A  86
 None
 0.90A 2xtkA-3prhA:
undetectable		 2xtkA-3prhA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		5 / 10 ILE A 284
VAL A  15
GLY A  18
VAL A  28
LEU A 249
 None
 1.28A 3elzC-3prhA:
undetectable		 3elzC-3prhA:
16.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		9 / 10 GLY A   8
GLN A  10
VAL A  41
HIS A  44
MET A 130
ASP A 133
ILE A 134
VAL A 142
GLN A 148
 None
 0.52A 3fhjA-3prhA:
40.3		 3fhjA-3prhA:
69.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		6 / 10 GLY A   8
VAL A  41
HIS A  44
MET A 130
ASP A 133
VAL A 142
 None
 1.06A 3fhjA-3prhA:
40.3		 3fhjA-3prhA:
69.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		9 / 10 GLY A   8
GLN A  10
VAL A  41
HIS A  44
MET A 130
ASP A 133
ILE A 134
VAL A 142
GLN A 148
 None
 0.59A 3fhjB-3prhA:
38.6		 3fhjB-3prhA:
69.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		6 / 10 GLY A   8
VAL A  41
HIS A  44
MET A 130
ASP A 133
VAL A 142
 None
 1.06A 3fhjB-3prhA:
38.6		 3fhjB-3prhA:
69.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		9 / 10 GLY A   8
GLN A  10
VAL A  41
HIS A  44
MET A 130
ASP A 133
ILE A 134
VAL A 142
GLN A 148
 None
 0.55A 3fhjC-3prhA:
37.3		 3fhjC-3prhA:
69.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		6 / 10 GLY A   8
VAL A  41
HIS A  44
MET A 130
ASP A 133
VAL A 142
 None
 1.06A 3fhjC-3prhA:
37.3		 3fhjC-3prhA:
69.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		8 / 9 GLY A   8
VAL A  41
HIS A  44
MET A 130
ASP A 133
ILE A 134
VAL A 142
GLN A 148
 None
 0.50A 3fhjD-3prhA:
38.9		 3fhjD-3prhA:
69.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		6 / 9 GLY A   8
VAL A  41
HIS A  44
MET A 130
ASP A 133
VAL A 142
 None
 1.06A 3fhjD-3prhA:
38.9		 3fhjD-3prhA:
69.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		9 / 10 GLY A   8
GLN A  10
VAL A  41
HIS A  44
MET A 130
ASP A 133
ILE A 134
VAL A 142
GLN A 148
 None
 0.51A 3fhjE-3prhA:
39.0		 3fhjE-3prhA:
69.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		6 / 10 GLY A   8
VAL A  41
HIS A  44
MET A 130
ASP A 133
VAL A 142
 None
 1.06A 3fhjE-3prhA:
39.0		 3fhjE-3prhA:
69.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		8 / 9 GLY A   8
VAL A  41
HIS A  44
MET A 130
ASP A 133
ILE A 134
VAL A 142
GLN A 148
 None
 0.50A 3fhjF-3prhA:
40.7		 3fhjF-3prhA:
69.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FHJ_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		6 / 9 GLY A   8
VAL A  41
HIS A  44
MET A 130
ASP A 133
VAL A 142
 None
 1.06A 3fhjF-3prhA:
40.7		 3fhjF-3prhA:
69.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		8 / 9 GLY A   8
GLN A  10
VAL A  41
HIS A  44
ASP A 133
ILE A 134
VAL A 142
GLN A 148
 None
 0.60A 3fi0A-3prhA:
39.8		 3fi0A-3prhA:
69.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		5 / 9 GLY A   8
VAL A  41
HIS A  44
ASP A 133
VAL A 142
 None
 0.99A 3fi0A-3prhA:
39.8		 3fi0A-3prhA:
69.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		6 / 8 GLY A   8
VAL A  41
HIS A  44
ASP A 133
ILE A 134
GLN A 148
 None
 0.41A 3fi0B-3prhA:
39.6		 3fi0B-3prhA:
69.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		6 / 8 GLY A   8
VAL A  41
HIS A  44
ASP A 133
ILE A 134
VAL A 142
 None
 0.39A 3fi0B-3prhA:
39.6		 3fi0B-3prhA:
69.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		8 / 9 GLY A   8
GLN A  10
VAL A  41
HIS A  44
ASP A 133
ILE A 134
VAL A 142
GLN A 148
 None
 0.61A 3fi0C-3prhA:
39.5		 3fi0C-3prhA:
69.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		5 / 9 GLY A   8
VAL A  41
HIS A  44
ASP A 133
VAL A 142
 None
 1.00A 3fi0C-3prhA:
39.5		 3fi0C-3prhA:
69.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		7 / 9 GLY A   8
GLN A  10
VAL A  41
HIS A  44
ASP A 133
ILE A 134
GLN A 148
 None
 0.75A 3fi0D-3prhA:
40.6		 3fi0D-3prhA:
69.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		7 / 9 GLY A   8
GLN A  10
VAL A  41
HIS A  44
ASP A 133
ILE A 134
VAL A 142
 None
 0.69A 3fi0D-3prhA:
40.6		 3fi0D-3prhA:
69.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		5 / 9 GLY A   8
VAL A  41
HIS A  44
ASP A 133
VAL A 142
 None
 1.01A 3fi0D-3prhA:
40.6		 3fi0D-3prhA:
69.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		6 / 7 GLY A   8
VAL A  41
HIS A  44
ASP A 133
ILE A 134
VAL A 142
 None
 0.43A 3fi0E-3prhA:
38.4		 3fi0E-3prhA:
69.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		4 / 7 VAL A  41
HIS A  44
ASP A 133
GLN A 148
 None
 0.56A 3fi0E-3prhA:
38.4		 3fi0E-3prhA:
69.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		8 / 9 GLY A   8
GLN A  10
VAL A  41
HIS A  44
ASP A 133
ILE A 134
VAL A 142
GLN A 148
 None
 0.71A 3fi0F-3prhA:
32.1		 3fi0F-3prhA:
69.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		5 / 9 GLY A   8
VAL A  41
HIS A  44
ASP A 133
VAL A 142
 None
 1.01A 3fi0F-3prhA:
32.1		 3fi0F-3prhA:
69.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_G_TRPG1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		6 / 8 GLY A   8
VAL A  41
HIS A  44
ASP A 133
ILE A 134
GLN A 148
 None
 0.49A 3fi0G-3prhA:
40.8		 3fi0G-3prhA:
69.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_G_TRPG1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		6 / 8 GLY A   8
VAL A  41
HIS A  44
ASP A 133
ILE A 134
VAL A 142
 None
 0.43A 3fi0G-3prhA:
40.8		 3fi0G-3prhA:
69.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_H_TRPH1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		8 / 9 GLY A   8
GLN A  10
VAL A  41
HIS A  44
ASP A 133
ILE A 134
VAL A 142
GLN A 148
 None
 0.48A 3fi0H-3prhA:
40.3		 3fi0H-3prhA:
69.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_J_TRPJ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		8 / 9 GLY A   8
GLN A  10
VAL A  41
HIS A  44
ASP A 133
ILE A 134
VAL A 142
GLN A 148
 None
 0.71A 3fi0J-3prhA:
40.0		 3fi0J-3prhA:
69.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_J_TRPJ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		5 / 9 GLY A   8
VAL A  41
HIS A  44
ASP A 133
VAL A 142
 None
 0.98A 3fi0J-3prhA:
40.0		 3fi0J-3prhA:
69.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_K_TRPK1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		8 / 9 GLY A   8
GLN A  10
VAL A  41
HIS A  44
ASP A 133
ILE A 134
VAL A 142
GLN A 148
 None
 0.55A 3fi0K-3prhA:
39.5		 3fi0K-3prhA:
69.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_K_TRPK1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		5 / 9 GLY A   8
VAL A  41
HIS A  44
ASP A 133
VAL A 142
 None
 1.02A 3fi0K-3prhA:
39.5		 3fi0K-3prhA:
69.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_L_TRPL1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		8 / 9 GLY A   8
GLN A  10
VAL A  41
HIS A  44
ASP A 133
ILE A 134
VAL A 142
GLN A 148
 None
 0.56A 3fi0L-3prhA:
40.6		 3fi0L-3prhA:
69.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_L_TRPL1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		5 / 9 GLY A   8
VAL A  41
HIS A  44
ASP A 133
VAL A 142
 None
 0.99A 3fi0L-3prhA:
40.6		 3fi0L-3prhA:
69.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_M_TRPM1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		8 / 9 GLY A   8
GLN A  10
VAL A  41
HIS A  44
ASP A 133
ILE A 134
VAL A 142
GLN A 148
 None
 0.55A 3fi0M-3prhA:
40.2		 3fi0M-3prhA:
69.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_M_TRPM1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		5 / 9 GLY A   8
VAL A  41
HIS A  44
ASP A 133
VAL A 142
 None
 1.00A 3fi0M-3prhA:
40.2		 3fi0M-3prhA:
69.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_N_TRPN1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		8 / 9 GLY A   8
GLN A  10
VAL A  41
HIS A  44
ASP A 133
ILE A 134
VAL A 142
GLN A 148
 None
 0.61A 3fi0N-3prhA:
40.3		 3fi0N-3prhA:
69.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_N_TRPN1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		5 / 9 GLY A   8
VAL A  41
HIS A  44
ASP A 133
VAL A 142
 None
 1.02A 3fi0N-3prhA:
40.3		 3fi0N-3prhA:
69.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_O_TRPO1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		8 / 9 GLY A   8
GLN A  10
VAL A  41
HIS A  44
ASP A 133
ILE A 134
VAL A 142
GLN A 148
 None
 0.59A 3fi0O-3prhA:
40.2		 3fi0O-3prhA:
69.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_O_TRPO1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		5 / 9 GLY A   8
VAL A  41
HIS A  44
ASP A 133
VAL A 142
 None
 1.03A 3fi0O-3prhA:
40.2		 3fi0O-3prhA:
69.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_P_TRPP1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		7 / 7 GLY A   8
GLN A  10
VAL A  41
HIS A  44
ASP A 133
ILE A 134
GLN A 148
 None
 0.64A 3fi0P-3prhA:
38.9		 3fi0P-3prhA:
69.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_Q_TRPQ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		7 / 8 GLY A   8
GLN A  10
VAL A  41
HIS A  44
ASP A 133
ILE A 134
VAL A 142
 None
 0.39A 3fi0Q-3prhA:
40.4		 3fi0Q-3prhA:
69.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_R_TRPR1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		7 / 9 GLY A   8
GLN A  10
VAL A  41
HIS A  44
ASP A 133
ILE A 134
VAL A 142
 None
 0.74A 3fi0R-3prhA:
37.7		 3fi0R-3prhA:
69.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_R_TRPR1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		7 / 9 GLY A   8
VAL A  41
HIS A  44
ASP A 133
ILE A 134
VAL A 142
GLN A 148
 None
 0.56A 3fi0R-3prhA:
37.7		 3fi0R-3prhA:
69.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FI0_R_TRPR1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		5 / 9 GLY A   8
VAL A  41
HIS A  44
ASP A 133
VAL A 142
 None
 0.95A 3fi0R-3prhA:
37.7		 3fi0R-3prhA:
69.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_A_0LIA1000_2
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		4 / 5 VAL A  48
ILE A  80
TYR A 126
ILE A  40
 None
 0.90A 4c8bA-3prhA:
undetectable		 4c8bA-3prhA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAH_C_RFPC3001_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		5 / 12 ARG A 299
LEU A 291
ARG A 287
PRO A  73
ILE A 300
 None
 1.28A 5uahC-3prhA:
undetectable		 5uahC-3prhA:
15.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V0I_A_TRPA402_0
(TRYPTOPHAN--TRNA
LIGASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		8 / 9 GLY A   8
GLN A  10
VAL A  41
HIS A  44
MET A 130
ASP A 133
ILE A 134
GLN A 148
 None
 0.60A 5v0iA-3prhA:
40.8		 5v0iA-3prhA:
49.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V0I_A_TRPA402_0
(TRYPTOPHAN--TRNA
LIGASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		8 / 9 GLY A   8
GLN A  10
VAL A  41
HIS A  44
MET A 130
ASP A 133
ILE A 134
VAL A 142
 None
 0.49A 5v0iA-3prhA:
40.8		 5v0iA-3prhA:
49.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V0I_B_TRPB402_0
(TRYPTOPHAN--TRNA
LIGASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		8 / 9 GLY A   8
GLN A  10
VAL A  41
HIS A  44
MET A 130
ASP A 133
ILE A 134
GLN A 148
 None
 0.61A 5v0iB-3prhA:
40.2		 5v0iB-3prhA:
49.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V0I_B_TRPB402_0
(TRYPTOPHAN--TRNA
LIGASE)		 3prh TRYPTOPHANYL-TRNA
SYNTHETASE
(Bacillus
subtilis) 		8 / 9 GLY A   8
GLN A  10
VAL A  41
HIS A  44
MET A 130
ASP A 133
ILE A 134
VAL A 142
 None
 0.51A 5v0iB-3prhA:
40.2		 5v0iB-3prhA:
49.21