SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3pru'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OIQ_A_STIA1001_2 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC)	3pru	PHYCOBILISOME 32.1 KDA LINKER POLYPEPTIDE, PHYCOCYANIN-ASSOCIAT ED, ROD 1 (Synechocystis sp. PCC 6803)	4 / 5	LEU C 29 VAL C 43 LEU C 44 ARG C 74	None	1.08A	2oiqA-3pruC: undetectable	2oiqA-3pruC: 18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YFB_A_ACTA501_0 (METHYL-ACCEPTING CHEMOTAXIS TRANSDUCER)	3pru	PHYCOBILISOME 32.1 KDA LINKER POLYPEPTIDE, PHYCOCYANIN-ASSOCIAT ED, ROD 1 (Synechocystis sp. PCC 6803)	5 / 7	ASP C 135 ARG C 70 VAL C 73 ARG C 74 TYR C 139	None	1.27A	2yfbA-3pruC: undetectable	2yfbA-3pruC: 18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YFB_B_ACTB501_0 (METHYL-ACCEPTING CHEMOTAXIS TRANSDUCER)	3pru	PHYCOBILISOME 32.1 KDA LINKER POLYPEPTIDE, PHYCOCYANIN-ASSOCIAT ED, ROD 1 (Synechocystis sp. PCC 6803)	5 / 6	ASP C 135 ARG C 70 VAL C 73 ARG C 74 TYR C 139	None	1.30A	2yfbB-3pruC: undetectable	2yfbB-3pruC: 18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JGL_B_SAMB301_1 (UBIE/COQ5 FAMILY METHYLTRANSFERASE, PUTATIVE)	3pru	PHYCOBILISOME 32.1 KDA LINKER POLYPEPTIDE, PHYCOCYANIN-ASSOCIAT ED, ROD 1 (Synechocystis sp. PCC 6803)	3 / 3	ASP C 129 ASN C 123 PHE C 91	None	0.91A	5jglB-3pruC: undetectable	5jglB-3pruC: 19.93

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2OIQ_A_STIA1001_2","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC","3pru","PHYCOBILISOME 32.1 KDA LINKER POLYPEPTIDE, PHYCOCYANIN-ASSOCIATED, ROD 1","Synechocystis sp. PCC 6803",4,"LEU C  29;VAL C  43;LEU C  44;ARG C  74","None","1.08A","2oiqA-3pruC:undetectable","2oiqA-3pruC:18.60"],["2YFB_A_ACTA501_0","METHYL-ACCEPTING CHEMOTAXIS TRANSDUCER","3pru","PHYCOBILISOME 32.1 KDA LINKER POLYPEPTIDE, PHYCOCYANIN-ASSOCIATED, ROD 1","Synechocystis sp. PCC 6803",5,"ASP C 135;ARG C  70;VAL C  73;ARG C  74;TYR C 139","None","1.27A","2yfbA-3pruC:undetectable","2yfbA-3pruC:18.01"],["2YFB_B_ACTB501_0","METHYL-ACCEPTING CHEMOTAXIS TRANSDUCER","3pru","PHYCOBILISOME 32.1 KDA LINKER POLYPEPTIDE, PHYCOCYANIN-ASSOCIATED, ROD 1","Synechocystis sp. PCC 6803",5,"ASP C 135;ARG C  70;VAL C  73;ARG C  74;TYR C 139","None","1.30A","2yfbB-3pruC:undetectable","2yfbB-3pruC:18.01"],["5JGL_B_SAMB301_1","UBIE\/COQ5 FAMILY METHYLTRANSFERASE, PUTATIVE","3pru","PHYCOBILISOME 32.1 KDA LINKER POLYPEPTIDE, PHYCOCYANIN-ASSOCIATED, ROD 1","Synechocystis sp. PCC 6803",3,"ASP C 129;ASN C 123;PHE C  91","None","0.91A","5jglB-3pruC:undetectable","5jglB-3pruC:19.93"]]