SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3prv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB503_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3prv NUCLEOSIDE
DIPHOSPHATE KINASE
(Trypanosoma
cruzi) 		4 / 6 ALA A  47
TYR A  66
ILE A  72
PRO A  42
 None
 1.18A 1oniB-3prvA:
undetectable
1oniC-3prvA:
undetectable		 1oniB-3prvA:
22.75
1oniC-3prvA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_H_BEZH515_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3prv NUCLEOSIDE
DIPHOSPHATE KINASE
(Trypanosoma
cruzi) 		4 / 6 ALA A  47
TYR A  66
ILE A  72
PRO A  42
 None
 1.16A 1oniH-3prvA:
undetectable
1oniI-3prvA:
undetectable		 1oniH-3prvA:
22.75
1oniI-3prvA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3prv NUCLEOSIDE
DIPHOSPHATE KINASE
(Trypanosoma
cruzi) 		5 / 12 GLY A  81
GLY A  79
GLY A  31
GLU A  78
VAL A  83
 None
 0.98A 2oxtA-3prvA:
undetectable		 2oxtA-3prvA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3prv NUCLEOSIDE
DIPHOSPHATE KINASE
(Trypanosoma
cruzi) 		5 / 12 GLY A  81
GLY A  79
GLY A  31
GLU A  78
VAL A  83
 None
 0.91A 2oxtC-3prvA:
undetectable		 2oxtC-3prvA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_A_NCAA1201_0
(TANKYRASE-2)		 3prv NUCLEOSIDE
DIPHOSPHATE KINASE
(Trypanosoma
cruzi) 		4 / 7 GLY A 118
ALA A 125
SER A 119
GLU A   4
 None
 0.91A 4hyfA-3prvA:
undetectable		 4hyfA-3prvA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_B_NCAB1201_0
(TANKYRASE-2)		 3prv NUCLEOSIDE
DIPHOSPHATE KINASE
(Trypanosoma
cruzi) 		4 / 8 GLY A 118
ALA A 125
SER A 119
GLU A   4
 None
 0.91A 4hyfB-3prvA:
undetectable		 4hyfB-3prvA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_C_NCAC1201_0
(TANKYRASE-2)		 3prv NUCLEOSIDE
DIPHOSPHATE KINASE
(Trypanosoma
cruzi) 		4 / 8 GLY A 118
ALA A 125
SER A 119
GLU A   4
 None
 0.91A 4hyfC-3prvA:
undetectable		 4hyfC-3prvA:
22.62